公开(公告)号：US11814355B2

公开(公告)日：2023-11-14

申请号：US17173171

申请日：2021-02-10

Applicant: Anhui Qingyun Pharmaceutical and Chemical Co., Ltd.

Inventor： Huan Huang ,  Kai Li ,  Qingyun Huang ,  Fuming Zhan ,  Qingguo Huang

IPC: C07D215/14 ,  B01J31/12 ,  B01J27/24 ,  B01J23/30 ,  B01J27/232

CPC classification number: C07D215/14 ,  B01J23/30 ,  B01J27/232 ,  B01J27/24 ,  B01J31/121 ,  B01J31/122 ,  B01J31/128 ,  B01J2531/11 ,  B01J2531/12

Abstract: A method for synthesizing pitavastatin tert-butyl ester includes obtaining a substance B through reacting (4R-CIS)-6-chloromethyl-2,2-dimethyl-1,3-dioxolane-4-acetic acid tert-butyl ester with a substance A under the action of a first base catalyst, 5 oxidizing with an oxidizing agent to obtain a substance C, then reacting with 2-cyclopropyl-4-(4-fluorophenyl)-quinoline-3-formaldehyde under the action of a second base catalyst to obtain a substance D, and finally, carrying out an acid deprotection to obtain pitavastatin t-butyl ester. The reaction conditions of the present invention are mild and controllable, and the reaction conditions of the synthesis of the Julia olefination do 10 not require an ultra-low temperature reaction. The operation is convenient and simple, the stereoselectivity is good, the yield is high, and the synthesized pitavastatin t-butyl ester is a completely non-cis isomer, and its purity is high.

公开(公告)号：US20230249128A1

公开(公告)日：2023-08-10

申请号：US18299755

申请日：2023-04-13

Applicant: TAIYO KOGYO CORPORATION

Inventor： Kazuhiro Abe

IPC: B01D53/86 ,  C08K3/013 ,  B01D71/36 ,  B01J21/06 ,  B01J27/232 ,  B01J35/02 ,  B01J37/02 ,  B01J37/08 ,  C08K3/22 ,  C08L27/18 ,  B01J31/38 ,  B32B27/20 ,  B32B27/30 ,  B32B27/18 ,  C08J7/043

CPC classification number: B01D53/86 ,  C08K3/013 ,  B01D71/36 ,  B01J21/063 ,  B01J27/232 ,  B01J35/02 ,  B01J37/02 ,  B01J37/08 ,  C08K3/22 ,  C08L27/18 ,  B01J31/38 ,  B32B27/20 ,  B32B27/30 ,  B32B27/18 ,  C08J7/043 ,  C08K2003/2241 ,  Y02C20/30

Abstract: The following phenomenon occurring in a fluororesin membrane material using, as its main material, a PTFE having a photocatalyst layer on a surface thereof is prevented: the surface of the membrane material is contaminated after the lapse of some years from the start of its use. A photocatalyst layer arranged on the PTFE layer of a Type A membrane material is formed of a photocatalyst and fluororesins, and the fluororesins are formed of at least one of a FEP or a PFA, and a PTFE. Here, the amount of the PTFE is preferably larger than that of at least one of the FEP or the PFA, and the weight of the photocatalyst is preferably 40% or less with respect to the total weight of the photocatalyst and the fluororesins.

公开(公告)号：US20230192589A1

公开(公告)日：2023-06-22

申请号：US17925541

申请日：2021-05-20

Applicant: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION ,  SHOWA DENKO K.K.

Inventor： Makoto TOKUNAGA ,  Haruno MURAYAMA ,  Eiji YAMAMOTO ,  Jooyoung SHIM ,  Haruki MORI ,  Nao SHIRAKURA ,  Shinya TSUKAMOTO ,  Shohei NISHIZAWA ,  Kazuhiro KITAGAWA ,  Hiroshi UCHIDA

IPC: C07C67/317 ,  C07C67/333 ,  B01J31/24 ,  B01J31/02 ,  B01J27/232

CPC classification number: C07C67/317 ,  C07C67/333 ,  B01J31/2419 ,  B01J31/2423 ,  B01J31/0225 ,  B01J31/0244 ,  B01J27/232 ,  B01J2531/824 ,  B01J2531/004 ,  B01J2531/007 ,  B01J2231/49

Abstract: What is provided is a production method in which a vinyl acetate is reacted with a primary or secondary alcohol represented by Formula (1) and carbon monoxide to produce a first ester compound represented by Formula (2), and the first ester compound is reacted with an alcohol to produce a lactic acid ester represented by Formula (3) and an acetic acid ester represented by Formula (4).

公开(公告)号：US20230191373A1

公开(公告)日：2023-06-22

申请号：US18074494

申请日：2022-12-04

Applicant: Beijing University of Chemical Technology

Inventor： Junting Feng ,  Dianqing LI ,  Qian Wang ,  Jiaxuan Fan ,  Xiaoxue Yue ,  Yufei He ,  Yanan Liu

IPC: B01J27/232 ,  B01J37/00 ,  B01J37/04 ,  B01D53/14 ,  B01J35/00 ,  B01J21/02 ,  B01J23/00 ,  B01J38/02 ,  B01J38/48

CPC classification number: B01J27/232 ,  B01J37/0036 ,  B01J37/04 ,  B01D53/1425 ,  B01J35/004 ,  B01J21/02 ,  B01J23/007 ,  B01J38/02 ,  B01J38/48 ,  B01D2255/65 ,  B01D2255/902 ,  B01D2255/802 ,  B01D2257/504 ,  B01D2259/802

Abstract: The present invention discloses a catalyst for in-situ CO2 capture and coupling reduction with biomass oxidation, a preparation method therefor and an application thereof. The catalyst is applied to the coupling reaction of photocatalytic CO2 reduction and biomass oxidation. The preparation of the catalyst is to synthesize layered double hydroxides (LDHs) containing CO32− between layers by using coprecipitation method, hydrothermal method, sol-gel method and the like, wherein the chemical formula is [M1-x2+Mx3+(OH)2]x+(An−)x/n·mH2O, which has a thickness of 20-30 nm and an average particle diameter of 60-90 nm. Then metal ion vacancy defects are produced on LDHs laminate by using a NaOH/KOH selective etching to obtain the corresponding catalyst. The catalyst is used in photocatalytic reaction, characterized in that CO32− is continuously consumed in the reaction process, and the catalyst can absorb CO2 in the air for recovery after the reaction, and can be repeatedly used to continuously consume CO2 in the air, thus realizing the direct capture and effective utilization of CO2.

公开(公告)号：US20190194230A1

公开(公告)日：2019-06-27

申请号：US15927264

申请日：2018-03-21

Applicant: OLON S.p.A.

Inventor： Federico GASSA ,  Lazzaro FELICIANI ,  Alberto MAZZA ,  Marco QUARONI ,  Mara SADA ,  Giorgio BERTOLINI

IPC: C07F5/02 ,  C07C37/02 ,  C07C39/15 ,  C07C39/205 ,  B01J23/42 ,  B01J23/44 ,  B01J27/053 ,  B01J27/232

CPC classification number: C07F5/027 ,  B01J23/42 ,  B01J23/44 ,  B01J27/053 ,  B01J27/232 ,  C07B47/00 ,  C07C37/02 ,  C07C39/15 ,  C07C39/205 ,  C07C255/50 ,  C07F5/025

Abstract: The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):

公开(公告)号：US10071955B1

公开(公告)日：2018-09-11

申请号：US15678737

申请日：2017-08-16

Applicant: QIANJIANG YONGAN PHARMACEUTICAL CO., LTD.

Inventor： Yong Chen ,  Xiquan Fang ,  Shaobo Li

IPC: C07C309/00 ,  C07C303/02 ,  C07C303/22 ,  B01D15/36 ,  B01J49/53 ,  B01J27/232 ,  C07C303/44

CPC classification number: C07C303/02 ,  B01D15/362 ,  B01J27/232 ,  B01J49/53 ,  C07C303/22 ,  C07C303/32 ,  C07C303/44 ,  C07C309/14 ,  C07C309/08

Abstract: The high-yield circular production method of taurine includes the following steps: S1, ethylene oxide reacts with sodium bisulfite solution to generate sodium hydroxyethyl sulfonate; S2, sodium hydroxyethyl sulfonate obtained in S1 is subjected to ammonolysis reaction in ammonia, and ammonia gas is recycled through flash evaporation upon completion of the reaction; S3, a reaction solution obtained after flash evaporation in S2 is sent to pass through an acidic cation exchange resin column, a material liquid containing taurine is collected, the inactivated resin column is subjected to regeneration with sulfur dioxide or carbon dioxide aqueous solution, and an eluent acquired during regeneration can be recycled directly or recycled after treated by sulfur dioxide; S4, the material liquid collected in S3 is subjected to post treatment to acquire taurine.

公开(公告)号：US20180236439A1

公开(公告)日：2018-08-23

申请号：US15754261

申请日：2016-08-23

Applicant: BASF CORPORATION

Inventor： Rostam Jal MADON ,  Peter NAGEL ,  Keenan Lee DEUTSCH ,  Deepak S. THAKUR

IPC: B01J37/00 ,  B01J37/08 ,  B01J35/02 ,  B01J21/04 ,  B01J21/08 ,  B01J21/16 ,  B01J21/18 ,  B01J23/843 ,  B01J27/232 ,  C07C29/42 ,  C07C33/046

CPC classification number: B01J37/0045 ,  B01J21/04 ,  B01J21/08 ,  B01J21/16 ,  B01J21/18 ,  B01J23/8437 ,  B01J27/232 ,  B01J35/023 ,  B01J37/08 ,  C07C29/42 ,  C07C33/046

Abstract: A process of forming an ethynylation catalyst includes providing a slurry including water, a copper-containing material, a bismuth-containing material, a structural material, and a binder; spray-drying the slurry to form particles; and calcining the particles to form the ethynylation catalyst.

公开(公告)号：US20180117570A1

公开(公告)日：2018-05-03

申请号：US15667089

申请日：2017-08-02

Applicant: Silura Technologies, Inc

Inventor： Erik M. Freer ,  Wayne P. Schammel ,  Fabio R. Zurcher ,  Joel M. Cizeron ,  Jin Ki Hong ,  Anja Rumplecker ,  Sam Maurer ,  Joel Gamoras ,  Daniel Rosenberg ,  Erik C. Scher

IPC: B01J27/25 ,  B01J37/00 ,  B01J27/232 ,  B01J23/30 ,  C07C2/84 ,  C07C5/48 ,  B01J23/10 ,  B01J35/12 ,  B01J35/00 ,  B01J37/04 ,  B01J35/02 ,  B01J35/06 ,  B01J23/00 ,  B01J37/08 ,  C07C11/04

CPC classification number: B01J27/25 ,  B01J23/002 ,  B01J23/10 ,  B01J23/30 ,  B01J27/232 ,  B01J35/0006 ,  B01J35/026 ,  B01J35/06 ,  B01J35/12 ,  B01J37/0009 ,  B01J37/0036 ,  B01J37/04 ,  B01J37/08 ,  C07C2/84 ,  C07C5/48 ,  C07C2521/06 ,  C07C2523/02 ,  C07C2523/10 ,  C07C2523/30 ,  C07C2527/25 ,  Y02P20/52 ,  C07C11/04

Abstract: Catalysts, catalytic forms and formulations, and catalytic methods are provided. The catalysts and catalytic forms and formulations are useful in a variety of catalytic reactions, for example, the oxidative coupling of methane. Related methods for use and manufacture of the same are also disclosed.

公开(公告)号：US20170305816A1

公开(公告)日：2017-10-26

申请号：US15515703

申请日：2016-01-29

Applicant: SMH Co., Ltd

Inventor： Kongkiat SURIYE ,  Burin KHEMTHONG ,  Mathukorn SANWANICH

IPC: C07C6/04 ,  B01J23/30 ,  B01J37/08 ,  B01J37/02 ,  B01J37/04

CPC classification number: C07C6/04 ,  B01J23/007 ,  B01J23/02 ,  B01J23/24 ,  B01J23/30 ,  B01J23/32 ,  B01J27/232 ,  B01J27/25 ,  B01J29/076 ,  B01J29/163 ,  B01J29/166 ,  B01J29/48 ,  B01J29/69 ,  B01J29/7815 ,  B01J29/7876 ,  B01J37/0201 ,  B01J37/04 ,  B01J37/08 ,  B01J38/12 ,  C07C2521/04 ,  C07C2521/08 ,  C07C2521/10 ,  C07C2523/30 ,  C07C2527/232 ,  C07C2529/08 ,  C07C2529/16 ,  Y02P20/52 ,  Y02P20/584 ,  C07C11/06

Abstract: The present invention provides a catalyst comprising a transition metal, an inorganic support, a zeolite, and a layered double hydroxide. Using of the catalyst according to the present invention in an olefin production process exhibits high activity and high selectivity with decreased deactivation rate, therefore longer reaction cycle can be performed and catalyst life is prolonged.

公开(公告)号：US20170297009A1

公开(公告)日：2017-10-19

申请号：US15515720

申请日：2016-09-29

Applicant: SMH Co., Ltd

Inventor： Kongkiat SURIYE ,  Burin KHEMTHONG

IPC: B01J35/00 ,  B01J27/232 ,  B01J27/25 ,  C07C6/04 ,  B01J29/48 ,  B01J35/02 ,  B01J23/02 ,  B01J29/78 ,  B01J29/70 ,  B01J38/52

CPC classification number: B01J35/0006 ,  B01J23/007 ,  B01J23/02 ,  B01J23/24 ,  B01J23/32 ,  B01J27/232 ,  B01J27/25 ,  B01J29/076 ,  B01J29/163 ,  B01J29/166 ,  B01J29/48 ,  B01J29/69 ,  B01J29/7038 ,  B01J29/7815 ,  B01J29/7876 ,  B01J35/02 ,  B01J37/04 ,  B01J38/52 ,  C07C6/04 ,  C07C2521/08 ,  C07C2523/16 ,  C07C2523/30 ,  C07C2529/08 ,  Y02P20/52 ,  C07C11/06

Abstract: The present invention relates to a catalyst system for olefin metathesis, the catalyst system comprising: a) a first system zone substantially comprising a layered double hydroxide; and b) a second system zone comprising a metathesis catalyst.