公开(公告)号：US20080003640A1

公开(公告)日：2008-01-03

申请号：US11316818

申请日：2005-12-27

申请人： Wen-Huei Hsu ,  Shih-Kuang Hsu

发明人： Wen-Huei Hsu ,  Shih-Kuang Hsu

IPC分类号： C12N9/90 ,  C12N15/61 ,  C12P13/22 ,  C12N15/63

CPC分类号： C12N9/90 ,  C12P13/222

摘要： The present invention relates to a novel thermostable N-acylamino acid racemase (NAAAR) isolated from Deinococcus radiodurans NCHU1003, the coding sequence and the preparation theraof. The present invention also discloses the process for preparing highly optically pure L-amino acids, such as L-homophenylalanine (L-HPA) and the derivatives thereof, from N-protected amino acid by using the novel NAAAR combined with L-N-carbamoylase.

摘要翻译： 本发明涉及从放线杆菌NCHU1003分离的新型热稳定N-酰基氨基酸消旋酶（NAAAR），其编码序列和制备方法。 本发明还公开了使用新的NAAAR与L-N-氨基甲酰基酶组合，从N-保护的氨基酸制备高光学纯的L-氨基酸，如L-高苯丙氨酸（L-HPA）及其衍生物的方法。

公开(公告)号：US07629154B2

公开(公告)日：2009-12-08

申请号：US11316818

申请日：2005-12-27

申请人： Wen-Huei Hsu ,  Shih-Kuang Hsu

发明人： Wen-Huei Hsu ,  Shih-Kuang Hsu

IPC分类号： C12P13/04 ,  C12P19/34 ,  C07H21/00

CPC分类号： C12N9/90 ,  C12P13/222

摘要： The present invention relates to a novel thermostable N-acylamino acid racemase (NAAAR) isolated from Deinococcus radiodurans NCHU1003, the coding sequence and the preparation thereof. The present invention also discloses the process for preparing highly optically pure L-amino acids, such as L-homophenylalanine (L-HPA) and the derivatives thereof, from N-protected amino acid by using the novel NAAAR combined with L-N-carbamoylase.

摘要翻译： 本发明涉及从放线杆菌NCHU1003分离的新型热稳定N-酰基氨基酸消旋酶（NAAAR），其编码序列及其制备。 本发明还公开了使用新的NAAAR与L-N-氨基甲酰基酶组合，从N-保护的氨基酸制备高光学纯的L-氨基酸，如L-高苯丙氨酸（L-HPA）及其衍生物的方法。