公开(公告)号：US09687516B2

公开(公告)日：2017-06-27

申请号：US14110611

申请日：2012-03-08

申请人： Yanwen Liu ,  Shuhe Chen ,  Hui Wang ,  Yaping Li ,  Lu Zhou ,  Wenying Zhang ,  Wei Liu

发明人： Yanwen Liu ,  Shuhe Chen ,  Hui Wang ,  Yaping Li ,  Lu Zhou ,  Wenying Zhang ,  Wei Liu

IPC分类号： A61K36/36 ,  A61K36/538 ,  A61K36/355 ,  A61K9/00

CPC分类号： A61K36/538 ,  A61K9/0031 ,  A61K36/355 ,  A61K36/36 ,  A61K2236/00

摘要： A preparation method for extractive botanicals includes: (A) honeysuckle, schizonepeta, and purslane in a powder are mixed, ground, and passed through a mesh; the medicinal powder obtained from supercritical extraction is soaked in alcohol, then undergoes percolation extraction, and the percolate is collected; (B) the alcohol percolate is concentrated, left stand, and suction filtrated to obtain a filtrate; (C) the filtrate macroporously adsorbs to a resin column at a flow velocity, is then removed of impurity by water washing, and undergoes elution with alcohol to obtain an alcohol eluent; (D) alcohol is recovered from the eluent, the remaining liquid is concentrated, and the concentrated liquid is dried to obtain the extractive of botanicals. The total content of flavones, saponins, and organic acids exceeds 70%. The extractive has substantial anti-inflammatory and pain relieving effects.

公开(公告)号：US20140087010A1

公开(公告)日：2014-03-27

申请号：US14110611

申请日：2012-03-08

申请人： Yanwen Liu ,  Shuhe Chen ,  Hui Wang ,  Yaping Li ,  Lu Zhou ,  Wenying Zhang ,  Wei Liu

发明人： Yanwen Liu ,  Shuhe Chen ,  Hui Wang ,  Yaping Li ,  Lu Zhou ,  Wenying Zhang ,  Wei Liu

IPC分类号： A61K36/538 ,  A61K36/355 ,  A61K36/36

CPC分类号： A61K36/538 ,  A61K9/0031 ,  A61K36/355 ,  A61K36/36 ,  A61K2236/00

摘要： The present invention discloses a preparation method for extractive of Jinxuan Hemorrhoid Washing Powder botanicals comprises the steps: A, honeysuckle, schizonepeta, and purslane in the prescription of Jinxuan Hemorrhoid Washing Powder are mixed, ground, and passed through a mesh; the medicinal powder obtained from supercritical extraction is soaked in alcohol, then undergoes percolation extraction, and the percolate is collected; B, the alcohol percolate is concentrated, left stand, and suction filtrated to obtain a filtrate; C, the filtrate macroporously adsorpts to a resin column at a flow velocity, is then removed of to impurity by water washing, and undergoes elution with alcohol to obtain an alcohol eluent; D, alcohol is recovered from the eluent, the remaining liquid is concentrated, and the concentrated liquid is dried to obtain the extractive of Jinxuan Hemorrhoid Washing Powder botanicals. The method is simple and produces high active substance content at a lower production cost and energy consumption. The total content of flavones, saponins, and organic acids exceeds 70%. The extractive has substantial anti-inflammatory and pain relieving effects.

摘要翻译： 本发明公开了一种提取金uan痔清洗粉植物药物的制备方法，其中金uan痔疮洗剂粉末处方中的A，金银花，蛇纹石和马齿苋均匀混合，研磨，通过筛网; 从超临界萃取得到的药粉浸泡在酒精中，然后进行渗滤提取，收集渗滤液; B，酒精浓缩，静置，抽滤，得到滤液; C，以流速大量吸附到树脂柱上的滤液然后通过水洗除去杂质，并用乙醇洗脱得到醇洗脱剂; D，从洗脱液中回收酒精，浓缩剩余液体，干燥浓缩液，得到金uan痔疮清洗剂植物提取物。 该方法简单，生产成本低，能耗高，活性物质含量高。 黄酮，皂苷和有机酸的总含量超过70％。 提取物具有显着的抗炎和止痛作用。