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公开(公告)号:US20110104765A1
公开(公告)日:2011-05-05
申请号:US12916318
申请日:2010-10-29
IPC分类号: C07C231/12 , C07C231/14 , C07C231/24 , C07C67/31 , C07C67/317 , C07C227/18 , C07C237/20 , C12P13/02 , C07C253/00 , C07C255/42 , C07C255/44
CPC分类号: C07C255/44 , C07B2200/07 , C07C227/20 , C07C227/32 , C07C229/36 , C07C231/06 , C07C231/12 , C07C231/18 , C07C231/24 , C07C237/20 , C07C249/02 , C07C251/24 , C07C253/00 , C07C255/43
摘要: Provided herein are compositions including diastereomers in substantially diastereomerically pure form and enantiomers in substantially enantiomerically pure form, and processes for preparing them and converting them to metyrosine.
摘要翻译: 本文提供了包括基本上非对映体纯的形式的非对映异构体和基本上对映体纯的形式的对映异构体的组合物,以及制备它们并将其转化为甲基酪氨酸的方法。
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公开(公告)号:US08841486B2
公开(公告)日:2014-09-23
申请号:US12916318
申请日:2010-10-29
IPC分类号: C07C221/00 , C07C223/00 , C07C225/00 , C07C255/43 , C07C231/06 , C07C227/20 , C07C237/20 , C07C231/24 , C07C253/00 , C07C231/12 , C07C249/02 , C07C251/24 , C07C227/32 , C07C229/36 , C07C231/18
CPC分类号: C07C255/44 , C07B2200/07 , C07C227/20 , C07C227/32 , C07C229/36 , C07C231/06 , C07C231/12 , C07C231/18 , C07C231/24 , C07C237/20 , C07C249/02 , C07C251/24 , C07C253/00 , C07C255/43
摘要: Provided herein are compositions including diastereomers in substantially diastereomerically pure form and enantiomers in substantially enantiomerically pure form, and processes for preparing them and converting them to metyrosine.
摘要翻译: 本文提供了包括基本上非对映体纯的形式的非对映异构体和基本上对映体纯的形式的对映异构体的组合物,以及制备它们并将其转化为甲基酪氨酸的方法。
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公开(公告)号:US09580427B2
公开(公告)日:2017-02-28
申请号:US14118541
申请日:2012-05-16
IPC分类号: C07D487/04 , A61K31/519 , A61P35/02 , A61P35/04 , C07D471/04 , C07D215/54 , C07D235/08 , C07D403/04 , C07D405/12 , C07D405/14 , C07D417/12 , C07D239/48 , C07D239/94 , C07D401/12 , C07D401/14 , C07D403/12 , A61P35/00
CPC分类号: C07D487/04 , C07D215/54 , C07D235/08 , C07D239/48 , C07D239/94 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D417/12 , C07D471/04
摘要: Provided herein are compounds such as the compounds having the structure of Formula (XI) and methods of using the same, such as methods of inhibiting kinases.
摘要翻译: 本文提供了激酶抑制化合物及其使用方法。
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公开(公告)号:US20130035325A1
公开(公告)日:2013-02-07
申请号:US13510272
申请日:2010-11-16
申请人: John William Taunton, JR. , Rebecca Maglathlin , Iana Serafimova , Michael S. Cohen , Rand Miller , Ville Paavilainen , Jesse McFarland , Shyam Krishnan
发明人: John William Taunton, JR. , Rebecca Maglathlin , Iana Serafimova , Michael S. Cohen , Rand Miller , Ville Paavilainen , Jesse McFarland , Shyam Krishnan
IPC分类号: A61K31/519 , A61K31/52 , C07D471/04 , A61K31/437 , C07D231/56 , A61K31/416 , C07D403/10 , C07D473/34 , C07D207/16 , A61K31/40 , C07D487/04 , A61K31/5377 , A61P35/00 , A61P37/00 , A61P31/18 , A61P29/00 , C12N9/99 , C07D473/00
CPC分类号: C07D487/04 , C07D207/416 , C07D231/56 , C07D471/04 , C07D473/00 , C07D473/34
摘要: Methods of inhibiting kinases using kinase inhibitors having olefin moieties are disclosed.
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公开(公告)号:US07773003B1
公开(公告)日:2010-08-10
申请号:US12398189
申请日:2009-03-05
IPC分类号: H03M7/40
摘要: A method for decoding an input bit stream encoded using Huffman encoding generates a lookup table using a standard Huffman code book. Thereafter, at least three bits are extracted from the input bit stream. The at least three bits extracted are used to traverse the lookup table. Subsequently, a data set corresponding to a Huffman code word is accessed, thereby decoding the input bit stream.
摘要翻译: 用于对使用霍夫曼编码编码的输入比特流进行解码的方法使用标准霍夫曼码书生成查找表。 此后,从输入比特流中提取至少三个比特。 提取的至少三个比特用于遍历查找表。 随后,访问与霍夫曼码字相对应的数据集,从而解码输入比特流。
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