CONNECTOR SYSTEM WITH RELEASABLE CONTOUR SEAL FOR A FLUID SYSTEM

    公开(公告)号:US20230116716A1

    公开(公告)日:2023-04-13

    申请号:US17904870

    申请日:2021-02-23

    IPC分类号: A61M39/10

    摘要: A connector system providing a releasable, liquid-tight seal for a fluid system is provided. The system includes a female connector, having a cylindrical opening, and a male connector, having a tubular end section, which is to be inserted in an insertion direction into the cylindrical opening. Inside the tubular end section, a fluid passage is formed. On an outer circumferential surface of the tubular end section, annular protrusions are integrally formed. When the tubular end section with the annular protrusions is inserted into the cylindrical opening, the intermediate protrusion and the rear protrusion each form a press-fit with the inner circumferential surface of the cylindrical opening, whereby a liquid-tight seal between the male connector and the female connector is generated.

    Method for deterministically reporting cause and effect in software systems

    公开(公告)号:US11599407B2

    公开(公告)日:2023-03-07

    申请号:US17279065

    申请日:2019-09-26

    发明人: Derek Haines

    IPC分类号: G06F11/00 G06F11/07 G06F16/23

    摘要: Negative outcomes experienced by a user in a live software system can be automatically, deterministically, and contemporaneously traced back to the root conditions that caused those outcomes, by generating causal event entries in a database for those root conditions as they occur, assigning unique causal IDs to those causal events, and propagating causal IDs alongside the software system state changes that are known to produce negative outcomes and which are effected by those root conditions. By selectively passing causal IDs based on the input and output values of the operation, subsequent causal events and negative outcomes can be linked accurately to causal IDs of parent events, making it simpler to trace negative outcomes for the user back to their root cause events in a software system.

    OPTICAL DISCRIMINATION APPARATUS AND METHODS ADAPTED TO MONITOR REACTIONS

    公开(公告)号:US20230064409A1

    公开(公告)日:2023-03-02

    申请号:US17759473

    申请日:2021-02-17

    摘要: An optical discrimination apparatus adapted for use in PCR testing and the like. The apparatus includes a multi-color light emitter to emit excitation light, a sample holder configured to hold dye-marked nucleic acid fragments in a PCR solution at a position configured to receive the excitation light along a first direction, light emission collection optics configured to collect scattered excitation light and light emission (fluorescent emission) from the sample holder along a second direction that is approximately orthogonal to the first direction, a spectrally-dispersive element configured to spectrally disperse scattered light and emission light, and a spectral detector configured to receive the separated emission light and excitation light on different photosites of the spectral detector. Systems and methods are provided, as are other aspects.

    Pretreatment agent in non-agglutination assays

    公开(公告)号:US11592439B2

    公开(公告)日:2023-02-28

    申请号:US16824136

    申请日:2020-03-19

    IPC分类号: G01N33/53 G01N33/94

    摘要: Methods and reagents are disclosed for minimizing a false result in an assay measurement for determining a concentration of an analyte in a sample suspected of containing the analyte. The method comprises pretreating both an antibody and a sample to be subjected to a non-agglutination immunoassay. In the method the antibody and the sample are combined with a pretreatment agent selected from the group consisting of hydroxyphenyl-substituted C1-C5 carboxylic acids and metallic salts thereof and halogen-substituted C1-C5 carboxylic acids and metallic salts thereof in an amount effective to enhance the accuracy of the non-agglutination immunoassay.

    LIQUID SUPPLY SYSTEMS, SPOUT SUPPORT TOOLS, AND METHODS OF USING

    公开(公告)号:US20230037693A1

    公开(公告)日:2023-02-09

    申请号:US17758726

    申请日:2020-07-02

    IPC分类号: B65D77/06 B65D25/44 F16L3/123

    摘要: Liquid supply system for an analyzer. Liquid supply system includes a liquid-containing container and a spout support tool. Liquid-containing container is made up of a rectangular parallelepiped box comprising a wall with an opening therein, and a collapsible insert including a liquid-containing portion received inside the rectangular parallelepiped box. The collapsible insert includes a spout with a flange wherein both are retractable through the opening. The support tool has a body having an engaging portion and a grasping portion, the engaging portion includes a first engagement surface engaged with a surface of the wall, a second engagement surface, and a spout receiver formed in the engaging portion that is configured to be received under the flange to support the spout. pout support tools and retaining methods of a liquid supply system are provided, as are other aspects.

    APPARATUS, SYSTEMS, AND METHODS OF TRANSFERRING LIQUIDS CONTAINING AGGREGATES

    公开(公告)号:US20230020665A1

    公开(公告)日:2023-01-19

    申请号:US17756254

    申请日:2020-11-18

    IPC分类号: G01N35/00 G01N33/543

    摘要: An apparatus configured to receive particles in a liquid includes: a housing comprising a housing inlet and a housing outlet; and a mesh located in the housing between the housing inlet and the housing outlet, the mesh having spaces greater than a greatest transverse dimension of the particles. The apparatus operates to break up agglomerates of the particles, such as agglomerates of magnetic particles. Other systems and methods of receiving and transferring liquids containing particles having a propensity to agglomerate are disclosed, as are other aspects.