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1.发明授权Antagonist antibodies directed against calcitonin gene-related peptide and methods using same 有权针对降钙素基因相关肽的拮抗剂抗体及使用其的方法公开(公告)号：US08007794B2
公开(公告)日：2011-08-30
申请号：US12093638
申请日：2006-11-02
申请人： Joerg Zeller , Kristian T. Poulsen , Yasmina Noubia Abdiche , Jaume Pons , Sierra Leigh Jones Collier , Arnon Rosenthal
发明人： Joerg Zeller , Kristian T. Poulsen , Yasmina Noubia Abdiche , Jaume Pons , Sierra Leigh Jones Collier , Arnon Rosenthal
IPC分类号： A61K39/395 , C07K16/18
CPC分类号： C07K16/18 , A61K31/4045 , A61K39/3955 , A61K2039/505 , C07K16/26 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/70 , C07K2317/71 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
摘要翻译： 本发明的特征在于通过施用抗CGRP拮抗剂抗体来预防或治疗CGRP相关疾病如血管舒缩症状，包括头痛（例如偏头痛，丛集性头痛和紧张性头痛）和热潮红的方法。 还描述了拮抗剂抗体G1和衍生自指向CGRP的G1的抗体。
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2.发明申请ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE AND METHODS USING SAME 有权针对CALCITONIN基因相关肽的ANTAGONIST抗体及其使用方法公开(公告)号：US20120009192A1
公开(公告)日：2012-01-12
申请号：US13179846
申请日：2011-07-11
申请人： Joerg Zeller , Kristian T. Poulsen , Yasmina N. Abdiche , Jaume Pons , Sierra Leigh Jones Collier , Arnon Rosenthal
发明人： Joerg Zeller , Kristian T. Poulsen , Yasmina N. Abdiche , Jaume Pons , Sierra Leigh Jones Collier , Arnon Rosenthal
CPC分类号： C07K16/18 , A61K31/4045 , A61K39/3955 , A61K2039/505 , C07K16/26 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/70 , C07K2317/71 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
摘要翻译： 本发明的特征在于通过施用抗CGRP拮抗剂抗体来预防或治疗CGRP相关疾病如血管舒缩症状，包括头痛（例如偏头痛，丛集性头痛和紧张性头痛）和热潮红的方法。 还描述了拮抗剂抗体G1和衍生自指向CGRP的G1的抗体。
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3.发明申请ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE AND METHODS USING SAME 有权针对CALCITONIN基因相关肽的ANTAGONIST抗体及其使用方法公开(公告)号：US20090220489A1
公开(公告)日：2009-09-03
申请号：US12093638
申请日：2006-11-02
申请人： Joerg Zeller , Kristian T. Poulsen , Yasmina Noubia Abdiche , Jaume Pons , Sierra Leigh Jones Collier , Arnon Rosenthal
发明人： Joerg Zeller , Kristian T. Poulsen , Yasmina Noubia Abdiche , Jaume Pons , Sierra Leigh Jones Collier , Arnon Rosenthal
IPC分类号： A61K39/395 , C07K16/18
CPC分类号： C07K16/18 , A61K31/4045 , A61K39/3955 , A61K2039/505 , C07K16/26 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/70 , C07K2317/71 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
摘要翻译： 本发明的特征在于通过施用抗CGRP拮抗剂抗体来预防或治疗CGRP相关疾病如血管舒缩症状，包括头痛（例如偏头痛，丛集性头痛和紧张性头痛）和热潮红的方法。 还描述了拮抗剂抗体G1和衍生自指向CGRP的G1的抗体。
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