公开(公告)号：US20120296207A1

公开(公告)日：2012-11-22

申请号：US13564713

申请日：2012-08-01

申请人： Ary S. Chernomorsky ,  James W. Vetter ,  Simon Chemomorsky

发明人： Ary S. Chernomorsky ,  James W. Vetter ,  Simon Chemomorsky

IPC分类号： A61B6/00

CPC分类号： A61M31/005 ,  A61B17/0057 ,  A61B90/39 ,  A61B2017/00654 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K49/04 ,  A61L31/146 ,  A61L31/18

摘要： An implant for filling a cavity created by an excisional procedure includes first and second portions. The first portion may include a first collagenous matrix that defines a first selected crosslinking density and the second portion may include a second collagenous matrix that defines a second selected cross-linking density that is different than the first cross-linking density. The first and second cross-linking densities may be selected so as to cause the first and second portions to swell in such a manner that the implant swells into a size and a shape that is similar to the predetermined size and shape of the cavity when the implant is implanted. An aqueous solution may be added to the cavity if the cavity is not sufficiently aqueous to cause the implant to swell.

摘要翻译： 用于填充由切除过程产生的空腔的植入物包括第一和第二部分。 第一部分可以包括限定第一选择的交联密度的第一胶原基质，并且第二部分可以包括限定不同于第一交联密度的第二选择的交联密度的第二胶原基质。 可以选择第一和第二交联密度以使得第一和第二部分以这样的方式膨胀，使得当第一和第二部分的膨胀成为与腔的预定尺寸和形状相似的尺寸和形状时，当 植入植入物。 如果空腔不足够水以引起植入物膨胀，则可将水溶液加入空腔中。