公开(公告)号：US20240277420A1

公开(公告)日：2024-08-22

申请号：US18596183

申请日：2024-03-05

Applicant: THE TRUSTEES OF DARTMOUTH COLLEGE

Inventor： Venkataramanan KRISHNASWAMY ,  Richard J. BARTH, JR. ,  Keith D. PAULSEN

IPC: A61B34/20 ,  A61B17/00 ,  A61B17/34 ,  A61B34/00 ,  A61B34/10 ,  A61B90/00 ,  G06T7/00 ,  G06T7/33

CPC classification number: A61B34/20 ,  A61B34/10 ,  A61B34/25 ,  A61B90/361 ,  G06T7/0012 ,  G06T7/33 ,  A61B2017/008 ,  A61B2017/3405 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/2065 ,  A61B2090/365 ,  A61B2090/378 ,  A61B2090/3908 ,  A61B2090/395 ,  G06T2207/30068

Abstract: A patient-specific device for guiding resection of a tumor located in local tissue of a patient includes a locator form and a surgical guidance cue. The locator form has a locator-form surface matching a surface of the local tissue of the patient near the tumor's location when the local tissue is imaged in a preoperative position, such that the locator form, when fit to the surface of the local tissue, restores the local tissue to the preoperative position. The surgical guidance cue is integrally formed with the locator form and based on images including only preoperative images of the local tissue in the preoperative position, to indicate a spatial property of the tumor in the preoperative position.

公开(公告)号：US12042772B2

公开(公告)日：2024-07-23

申请号：US18370462

申请日：2023-09-20

Applicant: Devicor Medical Products, Inc.

Inventor： Timothy Zimmer ,  Michelle Louise Johnson ,  Stephen D. Stallard

IPC: B01F31/00 ,  A61B90/00 ,  A61K49/22 ,  B01F23/23 ,  B01F31/65 ,  B01F35/22 ,  A47K5/12 ,  A61B8/08 ,  A61K49/00 ,  A61K49/04 ,  A61K49/18 ,  A61L31/14 ,  A61L31/18 ,  B01F101/00 ,  C08J9/30

CPC classification number: B01F31/65 ,  A61B90/39 ,  A61K49/226 ,  B01F23/2319 ,  B01F35/2206 ,  A47K5/1217 ,  A61B8/481 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3933 ,  A61B2090/3987 ,  A61K49/006 ,  A61K49/04 ,  A61K49/1803 ,  A61L31/145 ,  A61L31/146 ,  A61L31/148 ,  A61L31/18 ,  B01F2101/2202 ,  C08J9/30 ,  C08J2205/022 ,  C08J2207/10 ,  C08J2300/16

Abstract: A method and system are used to enhance a marker material to include a plurality of air bubbles. The method of manufacturing a marker includes enhancing a marker material to include a plurality of air bubbles using at least a first EFD and a second EFD. The method may include cycling repeatedly through a transfer process between a first container and a second container. A system for enhancing a marker material includes a transfer apparatus configured to receive a marker material and a selected amount of air. The system comprises a first EFD coupled to a first end of the transfer apparatus and a second EFD coupled to a second end of the transfer apparatus.

公开(公告)号：US20240238066A1

公开(公告)日：2024-07-18

申请号：US18154562

申请日：2023-01-13

Applicant: Martin A. Urban

Inventor： Martin A. Urban

IPC: A61B90/00

CPC classification number: A61B90/39 ,  A61B2090/3908 ,  A61B2090/3983 ,  A61B2090/3995

Abstract: A localization apparatus including a hollow localization wire and an internal wire. The hollow localization wire has a securing feature configured to secure the hollow localization wire in place relative to target tissue. The internal wire is disposed in the hollow localization wire. A distal end of the internal wire protruding from the hollow localization wire is configured to emit a signal permitting the target tissue to be located.

公开(公告)号：US11992349B2

公开(公告)日：2024-05-28

申请号：US18101032

申请日：2023-01-24

Applicant: Covidien LP

Inventor： Ron Barak ,  Oren P. Weingarten ,  Ariel Birenbaum ,  Guy Alexandroni

IPC: A61B5/00 ,  A61B6/00 ,  A61B6/02 ,  A61B6/12 ,  A61B6/46 ,  A61B34/20 ,  A61B90/00

CPC classification number: A61B6/12 ,  A61B6/00 ,  A61B6/022 ,  A61B6/463 ,  A61B6/466 ,  A61B6/487 ,  A61B6/5235 ,  A61B34/20 ,  A61B2034/2046 ,  A61B2034/2051 ,  A61B2034/2065 ,  A61B2090/367 ,  A61B2090/3762 ,  A61B2090/3908 ,  A61B2090/3966 ,  A61B2090/3983

Abstract: A system for constructing fluoroscopic-based three-dimensional volumetric data of a target area within a patient from two-dimensional fluoroscopic images including a structure of markers, a fluoroscopic imaging device configured to acquire a sequence of images of the target area and of the structure of markers, and a computing device. The computing device is configured to estimate a pose of the fluoroscopic imaging device for at least a plurality of images of the sequence of images based on detection of a possible and most probable projection of the structure of markers as a whole on each image of the plurality of images. The computing device is further configured to construct fluoroscopic-based three-dimensional volumetric data of the target area based on the estimated poses of the fluoroscopic imaging device.

公开(公告)号：US11963753B2

公开(公告)日：2024-04-23

申请号：US17099319

申请日：2020-11-16

Applicant: Cianna Medical, Inc.

Inventor： Eduardo Chi Sing ,  Mark A. Cole ,  Tommy G. Nguyen

IPC: A61B5/06 ,  A61B5/0507 ,  A61B90/00 ,  A61B17/00 ,  A61B34/20

CPC classification number: A61B5/061 ,  A61B5/0507 ,  A61B5/06 ,  A61B90/39 ,  A61B5/064 ,  A61B2017/00438 ,  A61B2017/00442 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B90/37 ,  A61B2090/3908 ,  A61B2090/397 ,  A61B2090/3975 ,  A61B2090/3987

Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.

公开(公告)号：US20240050190A1

公开(公告)日：2024-02-15

申请号：US18384839

申请日：2023-10-28

Applicant: TOPPAN INC.

Inventor： Saeko NOMURA ,  Ryo SHODA ,  Junya TANABE

IPC: A61B90/00

CPC classification number: A61B90/39 ,  A61B2090/397 ,  A61B2090/3908 ,  A61B2090/3991

Abstract: An examination marker for use in diagnostic imaging using microwaves. The examination marker includes a marker main body to be attached to an examination target. The marker main body is capable of displaying, on the marker main body, an index for use in scanning the examination target marker and is deformable following the shape of the examination target. The marker main body has a relative permittivity of 10 or less to microwaves at a frequency of 1 GHz.

公开(公告)号：US11872092B2

公开(公告)日：2024-01-16

申请号：US17095121

申请日：2020-11-11

Applicant: Board of Regents, The University of Texas System

Inventor： Baohong Yuan

IPC: A61B90/00 ,  A61B5/00 ,  A61B8/08 ,  A61K49/00 ,  A61K49/22

CPC classification number: A61B90/39 ,  A61B5/0071 ,  A61B8/481 ,  A61K49/0089 ,  A61K49/223 ,  A61K49/225 ,  A61B2090/3908 ,  A61B2090/3941 ,  A61B2090/3954 ,  A61B2090/3979

Abstract: A tissue implantation device comprises a capsule; and a population of ultrasound-switchable fluorophores incorporated in the capsule. A method of imaging a tissue implantation device in a biological environment comprises disposing the tissue implantation device in a biological environment, the population of ultrasound-switchable fluorophores having a switching threshold in the biological environment; exposing the biological environment to an ultrasound beam to form an activation region within the biological environment; switching the ultrasound-switchable fluorophores in the activation region from an off state to an on state; exciting the ultrasound-switchable fluorophores in the activation region with a beam of electromagnetic radiation; and detecting light emitted by the ultrasound-switchable fluorophores.

公开(公告)号：US20230329832A1

公开(公告)日：2023-10-19

申请号：US17772803

申请日：2020-10-21

Applicant: CLEMSON UNIVERSITY

Inventor： Scott R. SLANEY ,  Delphine DEAN

IPC: A61B90/00 ,  A61B34/20 ,  A61L31/18 ,  A61L31/12

CPC classification number: A61B90/39 ,  A61B34/20 ,  A61L31/18 ,  A61L31/124 ,  A61B2090/3908 ,  A61B2090/3954 ,  A61L2400/12 ,  A61B2034/2051

Abstract: Provided is an improved breast tissue marker and localization system and method of use. The breast tissue marker and localization system comprising a biocompatible marker and a detector. The biocompatible markers comprise a polymeric binder and a magnetically susceptible material such as an iron oxide nanoparticle wherein the biocompatible marker is suitable for implantation for localization of an area of pathological interest. The detector is capable of detecting a response magnetic field in said biocompatible marker.

公开(公告)号：US20230301743A1

公开(公告)日：2023-09-28

申请号：US18203846

申请日：2023-05-31

Applicant: Devicor Medical Products, Inc.

Inventor： John S. Fisher ,  Frederick A. Ahari

IPC: A61B90/00 ,  A61B17/34

CPC classification number: A61B90/39 ,  A61B17/3403 ,  A61B2090/3983 ,  A61B2090/3908 ,  A61B2090/3966 ,  A61B2090/3937 ,  A61B2090/3987 ,  A61B2010/045

Abstract: A method for marking a biopsy site after a biopsy has been performed includes the steps of placing a marker in the form of a semi-permeable membrane at the biopsy site so that the marker can be found at a later time, inserting a needle into the marker at the later time which is preferably immediately before a planned surgical resection of the biopsy site, and injecting a dye directly into the marker to color the marker. The semi-permeable qualities of the marker facilitate the slow egress of dye into tissue that is immediately adjacent the marker, enlarging the footprint of the marker. The semi-permeable membrane includes a high percentage of water after reaching osmotic equilibrium, rendering the marker highly visible under ultrasound imaging. The semi-permeable membrane may take the form of a fully or partially dehydrated hydrogel.

公开(公告)号：US11759232B2

公开(公告)日：2023-09-19

申请号：US17687993

申请日：2022-03-07

Applicant: Sang E Sim

Inventor： Sang E Sim

IPC: A61B17/34 ,  A61B90/00

CPC classification number: A61B17/3403 ,  A61B90/39 ,  A61B2017/3411 ,  A61B2090/3908 ,  A61B2090/3983 ,  A61B2090/3987

Abstract: A template grid which attaches to an ultrasound stepper of a transrectal ultrasound unit providing transperineal guidance and support through adjustable angle apertures allowing for accurate targeting of a medical implant such as a needle to its intended target such as for purposes of perirectal spacer placement. The rotational apertures allow for free adjustable changes in the trajectory of a medial implant such as a needle to its intended target while providing stability and support to the medical implant itself. The template grid, in addition, contains fixed apertures for placement of a medical implant such as a needle into the substance of the prostate gland positioned to avoid inadvertent passage through the urethra and rectum.