公开(公告)号：US20090093047A1

公开(公告)日：2009-04-09

申请号：US12182676

申请日：2008-07-30

申请人： Holger Klapproth ,  Sonja Bender Mohry

发明人： Holger Klapproth ,  Sonja Bender Mohry

IPC分类号： C12M1/34

CPC分类号： G01N21/76 ,  G01N21/05 ,  G01N33/54386 ,  G01N33/581 ,  G01N2333/902

摘要： A device for generating a chemiluminescence radiation depending on the binding of at least one ligand that is contained in a sample that is to be tested to at least one receptor that is binding-specific for the ligand has a flow cell having an internal cavity. The internal cavity has a separating wall on which the at least one receptor is immobilized. The internal cavity has at least two compartments. In a first compartment solid is deposited that contains at least one peroxidase-enzyme-possessing marker for marking the ligand in lyophilized form. A second compartment contains salt-stabilized luminol and a solid substance that releases hydrogen peroxide upon contact with water.

摘要翻译： 根据待测样品中所含的至少一种配体与至少一种对配体结合特异性的受体的结合产生化学发光辐射的装置具有具有内腔的流动池。 内腔具有分离壁，其上固定有至少一种受体。 内腔具有至少两个隔室。 在第一隔室中沉积含有至少一种含有冻干形式标记配体的过氧化物酶 - 酶标记物。 第二个隔间含有盐稳定的鲁米诺和与水接触时释放过氧化氢的固体物质。