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公开(公告)号：US20130072997A1
公开(公告)日：2013-03-21
申请号：US13547031
申请日：2012-07-11
IPC分类号： A61N1/36
CPC分类号： A61N1/36114 , A61N1/0551 , A61N1/056 , A61N1/36053 , A61N1/36135 , A61N1/36139
摘要： A method of treating autonomic imbalance in a patient includes energizing a first therapeutic element disposed in a superior vena cava of the patient to deliver therapy to a parasympathetic nerve fiber (e.g. vagus nerve), and energizing a second therapeutic element disposed within the superior vena cava to deliver therapy to a sympathetic cardiac nerve fiber. A neuromodulation system includes a parasympathetic therapy element adapted for positioning within a blood vessel, a sympathetic therapy element adapted for positioning within the blood vessel; and a stimulator to energize the parasympathetic therapy element to deliver parasympathetic therapy to a parasympathetic nerve fiber disposed external to the blood vessel and energize the sympathetic therapy element within the blood vessel to deliver sympathetic therapy to a sympathetic nerve fiber disposed external to the blood vessel. The therapy decreases the patient's heart rate and elevates or maintains the blood pressure of the patient.
摘要翻译： 一种治疗患者自主性不平衡的方法包括激励设置在患者上腔静脉中的第一治疗元件，以将治疗递送至副交感神经纤维（例如迷走神经），以及激励位于上腔静脉内的第二治疗元件 为交感神经纤维提供治疗。 神经调节系统包括适于定位在血管内的副交感神经治疗元件，适于定位在血管内的交感治疗元件; 以及刺激器，用于激励所述副交感神经治疗元件以将副交感神经治疗递送到设置在所述血管外部的副交感神经纤维，并激励所述血管内的所述交感神经治疗元件，以将交感神经治疗递送至设置在所述血管外部的交感神经纤维。 该疗法可降低患者的心率，提高或维持患者的血压。
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公开(公告)号：US08060218B2
公开(公告)日：2011-11-15
申请号：US11833101
申请日：2007-08-02
申请人： Udai Singh , Stephen C. Masson
发明人： Udai Singh , Stephen C. Masson
IPC分类号： A61N1/05
CPC分类号： A61N1/3758 , A61N1/3782 , A61N1/3956 , H01F17/043 , H01F27/26
摘要： An inductive element adapted for use in implantable intravascular devices (IIDs) having an elongate form factor with a cross-section. The inductive element includes a core that has an outer surface contour that corresponds to the form factor. A set of elongate, or oblong, windings are situated lengthwise along the major length dimension of the inductive element. The windings are also situated to direct a magnetic field along a radial direction in relation to the elongate form factor. In one embodiment the form factor is generally cylindrical and the cross-section is generally round.
摘要翻译： 适用于可植入的血管内装置（IID）的电感元件，其具有具有横截面的细长形状因子。 电感元件包括具有对应于外形的外表面轮廓的芯。 一组细长或长圆形的绕组沿电感元件的主长度尺寸纵向设置。 绕组也位于相对于细长形状因子沿径向引导磁场。 在一个实施例中，形状因子通常是圆柱形的，并且横截面通常是圆形的。
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公开(公告)号：US09067071B2
公开(公告)日：2015-06-30
申请号：US13547031
申请日：2012-07-11
CPC分类号： A61N1/36114 , A61N1/0551 , A61N1/056 , A61N1/36053 , A61N1/36135 , A61N1/36139
摘要： A method of treating autonomic imbalance in a patient includes energizing a first therapeutic element disposed in a superior vena cava of the patient to deliver therapy to a parasympathetic nerve fiber (e.g. vagus nerve), and energizing a second therapeutic element disposed within the superior vena cava to deliver therapy to a sympathetic cardiac nerve fiber. A neuromodulation system includes a parasympathetic therapy element adapted for positioning within a blood vessel, a sympathetic therapy element adapted for positioning within the blood vessel; and a stimulator to energize the parasympathetic therapy element to deliver parasympathetic therapy to a parasympathetic nerve fiber disposed external to the blood vessel and energize the sympathetic therapy element within the blood vessel to deliver sympathetic therapy to a sympathetic nerve fiber disposed external to the blood vessel. The therapy decreases the patient's heart rate and elevates or maintains the blood pressure of the patient.
摘要翻译： 一种治疗患者自主性不平衡的方法包括激励设置在患者上腔静脉中的第一治疗元件，以将治疗递送至副交感神经纤维（例如迷走神经），以及激励位于上腔静脉内的第二治疗元件 为交感神经纤维提供治疗。 神经调节系统包括适于定位在血管内的副交感神经治疗元件，适于定位在血管内的交感治疗元件; 以及刺激器，用于激励所述副交感神经治疗元件以将副交感神经治疗递送到设置在所述血管外部的副交感神经纤维，并激励所述血管内的所述交感神经治疗元件，以将交感神经治疗递送至设置在所述血管外部的交感神经纤维。 该疗法可降低患者的心率，提高或维持患者的血压。
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公开(公告)号：US08335571B2
公开(公告)日：2012-12-18
申请号：US13295916
申请日：2011-11-14
申请人： Udai Singh , Stephen C. Masson
发明人： Udai Singh , Stephen C. Masson
IPC分类号： A61N1/05
CPC分类号： A61N1/3758 , A61N1/3782 , A61N1/3956 , H01F17/043 , H01F27/26
摘要： An inductive element adapted for use in implantable intravascular devices (IIDs) having an elongate form factor with a cross-section. The inductive element includes a core that has an outer surface contour that corresponds to the form factor. A set of elongate, or oblong, windings are situated lengthwise along the major length dimension of the inductive element. The windings are also situated to direct a magnetic field along a radial direction in relation to the elongate form factor. In one embodiment the form factor is generally cylindrical and the cross-section is generally round.
摘要翻译： 适用于可植入的血管内装置（IID）的电感元件，其具有具有横截面的细长形状因子。 电感元件包括具有对应于外形的外表面轮廓的芯。 一组细长或长圆形的绕组沿电感元件的主长度尺寸纵向设置。 绕组也位于相对于细长形状因子沿径向引导磁场。 在一个实施例中，形状因子通常是圆柱形的，并且横截面通常是圆形的。
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公开(公告)号：US20130072995A1
公开(公告)日：2013-03-21
申请号：US13547035
申请日：2012-07-11
IPC分类号： A61N1/36
CPC分类号： A61N1/056 , A61B5/0215 , A61N1/3605 , A61N1/36114 , A61N1/36564
摘要： A neuromodulation system includes a first therapy element adapted for positioning within a superior vena cava, and a second therapy element adapted for positioning within a pulmonary artery. Each therapy element is carried on a corresponding elongate flexible shaft. One of the shafts is slidably received within a lumen of the other so that the second therapy element may be advanced within the body relative to the first. A stimulator energizes the first therapy element within the first blood vessel to deliver therapy to a first nerve fiber disposed external to the superior vena cava and to energize the second therapy element within the pulmonary artery to deliver sympathetic therapy to a second nerve fiber disposed external to the pulmonary artery. For treatment of heart failure, the first nerve fiber may be a vagus nerve and the second nerve fiber may be a sympathetic nerve fiber.
摘要翻译： 神经调节系统包括适于定位在上腔静脉内的第一治疗元件和适于定位在肺动脉内的第二治疗元件。 每个治疗元件承载在相应的细长柔性轴上。 一个轴可滑动地容纳在另一个的内腔中，使得第二治疗元件可相对于第一治疗元件在主体内前进。 刺激器对第一血管内的第一治疗元件通电，以将治疗递送至布置在上腔静脉外部的第一神经纤维，并且激励肺动脉内的第二治疗元件，以将交感神经治疗递送至外部设置的第二神经纤维 肺动脉。 为了治疗心力衰竭，第一神经纤维可能是迷走神经，第二神经纤维可能是交感神经纤维。
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公开(公告)号：US20120130441A1
公开(公告)日：2012-05-24
申请号：US13295916
申请日：2011-11-14
申请人： Udai Singh , Stephen C. Masson
发明人： Udai Singh , Stephen C. Masson
IPC分类号： A61N1/39
CPC分类号： A61N1/3758 , A61N1/3782 , A61N1/3956 , H01F17/043 , H01F27/26
摘要： An inductive element adapted for use in implantable intravascular devices (IIDs) having an elongate form factor with a cross-section. The inductive element includes a core that has an outer surface contour that corresponds to the form factor. A set of elongate, or oblong, windings are situated lengthwise along the major length dimension of the inductive element. The windings are also situated to direct a magnetic field along a radial direction in relation to the elongate form factor. In one embodiment the form factor is generally cylindrical and the cross-section is generally round.
摘要翻译： 适用于可植入的血管内装置（IID）的电感元件，其具有具有横截面的细长形状因子。 电感元件包括具有对应于外形的外表面轮廓的芯。 一组细长或长圆形的绕组沿电感元件的主长度尺寸纵向设置。 绕组也位于相对于细长形状因子沿径向引导磁场。 在一个实施例中，形状因子通常是圆柱形的，并且横截面通常是圆形的。
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公开(公告)号：US20090036939A1
公开(公告)日：2009-02-05
申请号：US11833101
申请日：2007-08-02
申请人： Udai Singh , Stephen C. Masson
发明人： Udai Singh , Stephen C. Masson
IPC分类号： A61N1/362
CPC分类号： A61N1/3758 , A61N1/3782 , A61N1/3956 , H01F17/043 , H01F27/26
摘要： An inductive element adapted for use in implantable intravascular devices (IIDs) having an elongate form factor with a cross-section. The inductive element includes a core that has an outer surface contour that corresponds to the form factor. A set of elongate, or oblong, windings are situated lengthwise along the major length dimension of the inductive element. The windings are also situated to direct a magnetic field along a radial direction in relation to the elongate form factor. In one embodiment the form factor is generally cylindrical and the cross-section is generally round.
摘要翻译： 适用于可植入的血管内装置（IID）的电感元件，其具有具有横截面的细长形状因子。 电感元件包括具有对应于外形的外表面轮廓的芯。 一组细长或长圆形的绕组沿电感元件的主长度尺寸纵向设置。 绕组也位于相对于细长形状因子沿径向引导磁场。 在一个实施例中，形状因子通常是圆柱形的，并且横截面通常是圆形的。
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