公开(公告)号：US08278083B2

公开(公告)日：2012-10-02

申请号：US12225551

申请日：2007-03-23

Applicant: Yossef Raviv ,  Mathias Viard ,  Robert Blumenthal ,  Robert J. Hogan ,  Stephen Mark Tompkins

Inventor： Yossef Raviv ,  Mathias Viard ,  Robert Blumenthal ,  Robert J. Hogan ,  Stephen Mark Tompkins

IPC: A61K39/145 ,  C12N13/00

CPC classification number: A61K39/145 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/543 ,  C12N2740/15063 ,  C12N2740/16063 ,  C12N2760/14134 ,  C12N2760/14163 ,  C12N2760/16011 ,  C12N2760/16134 ,  C12N2760/16163 ,  C12N2760/16234

Abstract: The invention provides compositions of inactivated influenza virus that can be used as vaccines and immunological compositions useful for inhibiting, preventing and treating influenza.

Abstract translation: 本发明提供可用作疫苗的灭活流感病毒的组合物和用于抑制，预防和治疗流感的免疫组合物。

公开(公告)号：US20100204300A1

公开(公告)日：2010-08-12

申请号：US12522456

申请日：2008-01-16

Applicant: Stephen Mark Tompkins ,  Jeffrey Robert Hogan

Inventor： Stephen Mark Tompkins ,  Jeffrey Robert Hogan

IPC: A61K31/7105 ,  C07H21/02 ,  C12N15/74 ,  C12N5/10 ,  A61P31/12

CPC classification number: C12N15/1131 ,  C12N2310/14 ,  C12N2710/24122

Abstract: The instant disclosure relates to methods and compositions for silencing poxvirus gene expression and replication using RNA interference. In certain embodiments, the disclosure relates to methods of treating a subject with a poxvirus infection.

Abstract translation: 本公开涉及使用RNA干扰沉默痘病毒基因表达和复制的方法和组合物。 在某些实施方案中，本公开涉及用痘病毒感染治疗受试者的方法。

公开(公告)号：US20090297558A1

公开(公告)日：2009-12-03

申请号：US12225551

申请日：2007-03-23

Applicant: Yossef Raviv ,  Mathias Viard ,  Robert Blumenthal ,  Robert J. Hogan ,  Stephen Mark Tompkins

Inventor： Yossef Raviv ,  Mathias Viard ,  Robert Blumenthal ,  Robert J. Hogan ,  Stephen Mark Tompkins

IPC: A61K39/145 ,  C12N13/00 ,  A61P37/04

CPC classification number: A61K39/145 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/543 ,  C12N2740/15063 ,  C12N2740/16063 ,  C12N2760/14134 ,  C12N2760/14163 ,  C12N2760/16011 ,  C12N2760/16134 ,  C12N2760/16163 ,  C12N2760/16234

Abstract: The invention provides compositions of inactivated influenza virus that can be used as vaccines and immunological compositions useful for inhibiting, preventing and treating influenza.

Abstract translation: 本发明提供可用作疫苗的灭活流感病毒的组合物和用于抑制，预防和治疗流感的免疫组合物。