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1.发明申请Generating, viewing, interpreting, and utilizing a quantitive database of metabolites 审中-公开生成，观察，解释和利用代谢物的量化数据库公开(公告)号：US20110172926A1
公开(公告)日：2011-07-14
申请号：US12455586
申请日：2009-06-03
申请人： Steve M. Watkins
发明人： Steve M. Watkins
IPC分类号： G06F19/00
摘要： This disclosure provides methods for the creation of a quantitative database of metabolites, particularly lipid metabolites, using chromatographic technology; methods for assembling that information into a visual format for interpretation, and methods of this information to identify and understand metabolome-wide effects, for instance those effects influenced by pharmaceuticals, genes, toxins, diet or the environment. Also provided are metabolite databases, such as lipid metabolite databases, that are stored on a computer readable medium, which include quantitative measurements of a plurality of metabolites.
摘要翻译： 本公开提供了使用色谱技术创建代谢物，特别是脂质代谢物的定量数据库的方法; 将该信息组装成用于解释的视觉格式的方法以及该信息的方法来识别和理解代谢组学范围的影响，例如受药物，基因，毒素，饮食或环境影响的影响。 还提供了存储在计算机可读介质上的代谢物数据库，例如脂质代谢物数据库，其包括多种代谢物的定量测量。
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公开(公告)号：US20090239253A1
公开(公告)日：2009-09-24
申请号：US12271809
申请日：2008-11-14
申请人： Steve M. WATKINS
发明人： Steve M. WATKINS
IPC分类号： C12Q1/02
CPC分类号： G01N33/92 , G01N33/6893 , G01N2500/00 , G01N2800/042 , G01N2800/044
摘要： Described herein in various embodiments are methods for using quantitative and/or comparative lipid metabolite data, particularly for identifying and interpreting individual metabolomic profiles as indicative of metabolic status. The provided methods, for instance, allow analysis of the likelihood or progression of weight gain or weight loss, growth or wasting, obesity, diabetes, and aging in an individual based on measurements of the measurement of the quantity of one or more lipid biomarkers, profiles of such markers, or ratios of such markers.
摘要翻译： 本文在各种实施方案中描述了使用定量和/或比较脂质代谢物数据的方法，特别是用于鉴定和解释作为代谢状态指示的个体代谢组图。 所提供的方法例如允许基于测量一种或多种脂质生物标志物的量的测量来分析个体体重增加或体重减轻，生长或消瘦，肥胖，糖尿病和衰老的可能性或进展， 这些标记的轮廓或这些标记的比例。
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公开(公告)号：US20090221081A1
公开(公告)日：2009-09-03
申请号：US12324017
申请日：2008-11-26
IPC分类号： G01N33/92
CPC分类号： G01N33/6893 , G01N33/92 , G01N2800/02 , G01N2800/044
摘要： The present invention provides methods of using certain metabolite markers for predicting weight development or its related conditions of a subject. The present invention also provides compositions and kits useful for detecting metabolite markers of the present invention.
摘要翻译： 本发明提供了使用某些代谢物标记物来预测受试者的体重发育或其相关状况的方法。 本发明还提供可用于检测本发明的代谢物标记物的组合物和试剂盒。
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4.发明授权Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes 有权蛋白质和脂质生物标志物提供对2型糖尿病预测的一致改善公开(公告)号：US09217747B2
公开(公告)日：2015-12-22
申请号：US13504720
申请日：2010-10-28
CPC分类号： G01N33/6893 , G01N33/66 , G01N33/92 , G01N2800/042 , G01N2800/50 , G06F19/00 , G16H50/50 , Y02A90/26
摘要： The invention relates to biomarkers associated with Diabetes, including protein and lipid metabolite biomarkers, methods of using the biomarkers to determine the risk that an individual will develop Diabetes, and methods of screening a population to identify persons at risk for developing Diabetes and other pre-diabetic conditions.
摘要翻译： 本发明涉及与糖尿病相关的生物标志物，包括蛋白质和脂质代谢物生物标志物，使用生物标志物来确定个体将发展成为糖尿病的风险的方法，以及筛选人群以识别处于发展中的糖尿病和其他预防患者的风险的人的方法， 糖尿病状况。
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5.发明申请PROTEIN AND LIPID BIOMARKERS PROVIDING CONSISTENT IMPROVEMENT TO THE PREDICTION OF TYPE 2 DIABETES 有权蛋白质和脂质生物标志物提供一致性改进预测2型糖尿病公开(公告)号：US20120328594A1
公开(公告)日：2012-12-27
申请号：US13504720
申请日：2010-10-28
CPC分类号： G01N33/6893 , G01N33/66 , G01N33/92 , G01N2800/042 , G01N2800/50 , G06F19/00 , G16H50/50 , Y02A90/26
摘要： The invention relates to biomarkers associated with Diabetes, including protein and lipid metabolite biomarkers, methods of using the biomarkers to determine the risk that an individual will develop Diabetes, and methods of screening a population to identify persons at risk for developing Diabetes and other pre-diabetic conditions.
摘要翻译： 本发明涉及与糖尿病相关的生物标志物，包括蛋白质和脂质代谢物生物标志物，使用生物标志物来确定个体将发展成为糖尿病的风险的方法，以及筛选人群以识别处于发展中的糖尿病和其他预防患者的风险的人的方法， 糖尿病状况。
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