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公开(公告)号:US20050075488A1
公开(公告)日:2005-04-07
申请号:US10484280
申请日:2002-07-18
申请人: Stuart Bright , Audrey Jia , Stuart Kuhstoss , Joseph Vincent Manetta , Naoya Tsurushita , Maximiliano Vasquez
发明人: Stuart Bright , Audrey Jia , Stuart Kuhstoss , Joseph Vincent Manetta , Naoya Tsurushita , Maximiliano Vasquez
CPC分类号: C07K16/245 , A61K2039/505 , C07K2317/24 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76
摘要: The present invention encompasses high affinity antibodies that neutralize IL-1β activity in vivo. These antibodies can be used to treat various diseases such as rheumatoid arthritis and osteoarthritis.
摘要翻译: 本发明包括在体内中和IL-1β活性的高亲和力抗体。 这些抗体可用于治疗各种疾病,例如类风湿性关节炎和骨关节炎。