公开(公告)号：US09877673B2

公开(公告)日：2018-01-30

申请号：US13294368

申请日：2011-11-11

申请人： John F. Currie ,  Joseph A. Marcanio ,  Joseph J. Vidalis ,  Sundar B. Nadarajan

发明人： John F. Currie ,  Joseph A. Marcanio ,  Joseph J. Vidalis ,  Sundar B. Nadarajan

IPC分类号： A61B5/05 ,  A61B5/15 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/151 ,  A61B5/157 ,  A61B5/00

CPC分类号： A61B5/150022 ,  A61B5/0022 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150076 ,  A61B5/150122 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150854 ,  A61B5/150862 ,  A61B5/15087 ,  A61B5/150946 ,  A61B5/150984 ,  A61B5/15134 ,  A61B5/157 ,  A61B2562/0295

摘要： Transdermal sampling and analysis device, method and system are provided for non-invasively and transdermally obtaining biological samples from a subject and determining levels of analytes of the obtained biological samples. The transdermal sampling and analysis device, method and system may cause disruption to the skin cells to create capillary-like channels from which biological samples may flow to the transdermal sampling and analysis device. The transdermal sampling and analysis device, method and system may collect the biological samples in a reservoir where the biological sample may chemically react with a biologically reactive element. A sensor may convert the produced electrons (ions) into measured electrical signals. The converted signals may be measured and the levels of an analyte may be determined based on the measured signals.

公开(公告)号：US20120150004A1

公开(公告)日：2012-06-14

申请号：US13294368

申请日：2011-11-11

申请人： John F. Currie ,  Joseph A. Marcanio ,  Joseph J. Vidalis ,  Sundar B. Nadarajan

发明人： John F. Currie ,  Joseph A. Marcanio ,  Joseph J. Vidalis ,  Sundar B. Nadarajan

IPC分类号： A61B5/157

CPC分类号： A61B5/150022 ,  A61B5/0022 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150076 ,  A61B5/150122 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150854 ,  A61B5/150862 ,  A61B5/15087 ,  A61B5/150946 ,  A61B5/150984 ,  A61B5/15134 ,  A61B5/157 ,  A61B2562/0295

摘要： Transdermal sampling and analysis device, method and system are provided for non-invasively and transdermally obtaining biological samples from a subject and determining levels of analytes of the obtained biological samples. The transdermal sampling and analysis device, method and system may cause disruption to the skin cells to create capillary-like channels from which biological samples may flow to the transdermal sampling and analysis device. The transdermal sampling and analysis device, method and system may collect the biological samples in a reservoir where the biological sample may chemically react with a biologically reactive element. A sensor may convert the produced electrons (ions) into measured electrical signals. The converted signals may be measured and the levels of an analyte may be determined based on the measured signals.

摘要翻译： 提供透皮取样和分析装置，方法和系统非侵入性地和经皮地获得来自受试者的生物样品，并确定获得的生物样品的分析物水平。 透皮取样和分析装置，方法和系统可能导致皮肤细胞的破坏，从而产生毛细管样通道，生物样品可以从该细胞流动到透皮取样和分析装置。 透皮采样和分析装置，方法和系统可以将生物样品收集在储存器中，其中生物样品可以与生物反应性元件发生化学反应。 传感器可以将产生的电子（离子）转换成测量的电信号。 可以测量转换的信号，并且可以基于测量的信号来确定分析物的水平。