公开(公告)号：US20110251082A1

公开(公告)日：2011-10-13

申请号：US12756927

申请日：2010-04-08

Applicant: Hong-Lin Chan ,  Hsiu-Chuan Chou ,  Tzu-Chia Lai ,  Yi-Wen Chen ,  Ping-Chiang Lyu ,  Tian -Ren Lee ,  Hsin-Tsu Chan ,  Hsin-Hsin Shen ,  Wei-Ta Lee ,  Szu-Ting Lin ,  Ying-Chieh Lu ,  Chieh-Lin Wu

Inventor： Hong-Lin Chan ,  Hsiu-Chuan Chou ,  Tzu-Chia Lai ,  Yi-Wen Chen ,  Ping-Chiang Lyu ,  Tian -Ren Lee ,  Hsin-Tsu Chan ,  Hsin-Hsin Shen ,  Wei-Ta Lee ,  Szu-Ting Lin ,  Ying-Chieh Lu ,  Chieh-Lin Wu

IPC: C40B30/04 ,  C40B30/00 ,  C40B40/10

CPC classification number: G01N33/57415 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/56

Abstract: The present invention uses 2-dimensional differential gel electrophoresisgel (2D-DIGE) and mass spetrum techniques to identify breast cancer biomarkers in transformed breast cells. In summary, the present invention identifies numerous putative breast cancer markers from various stages of breast cancer. The results of the invention aids in developing proteins identified as useful diagnostic and therapeutic candidates on breast cancer research.

Abstract translation: 本发明使用二维差示凝胶电泳凝胶（2D-DIGE）和大量的突出技术来鉴定转化的乳腺细胞中的乳腺癌生物标志物。 总之，本发明从乳腺癌的各个阶段鉴定出许多推定的乳腺癌标志物。 本发明的结果有助于开发鉴定为乳腺癌研究中有用的诊断和治疗候选物的蛋白质。