公开(公告)号：US09023287B2

公开(公告)日：2015-05-05

申请号：US13634331

申请日：2010-11-12

申请人： Takahiro Kozuka

发明人： Takahiro Kozuka

IPC分类号： B01J19/18 ,  C08F8/12

CPC分类号： C08F8/12 ,  C08F18/04

摘要： Provided is a method and an apparatus for producing a polyvinyl alcohol that can reduce energy consumption without deterioration in quality of the product polyvinyl alcohol. First, one or more vinyl esters are polymerized or a vinyl ester and other copolymerizable monomers are copolymerized to give a polyvinyl ester. Then, a raw saponification solution containing the polyvinyl ester and an organic solvent is fed through a channel 1 and a saponification catalyst-containing solution is introduced into the center of the channel. They are then mixed with static mixers 2 and the mixture 4 is subjected to saponification reaction, as it is placed on a belt 3.

摘要翻译： 提供一种可以降低能量消耗而不会使产品聚乙烯醇的质量下降的聚乙烯醇的制造方法和装置。 首先，聚合一种或多种乙烯基酯，或将乙烯基酯和其它可共聚单体共聚以得到聚乙烯酯。 然后，将含有聚乙烯基酯和有机溶剂的原始皂化溶液通过通道1进料，并将含皂化催化剂的溶液引入通道的中心。 然后将它们与静态混合器2混合，并将混合物4放置在带3上进行皂化反应。

公开(公告)号：US20130005906A1

公开(公告)日：2013-01-03

申请号：US13634322

申请日：2010-12-06

申请人： Takahiro Kozuka

发明人： Takahiro Kozuka

IPC分类号： B01D3/18 ,  C08F16/06

CPC分类号： B01D3/343 ,  B01D3/22 ,  C08F6/003 ,  C08F8/12 ,  C08F118/08 ,  C08F216/06 ,  C08L29/04

摘要： Provided are an apparatus for removing residual monomers and a method of producing a polyvinyl alcohol resin that can prevent drift of the organic solvent gas and residual of the polymerization solution on the trays and permits efficient removal of the unreacted monomers from the polymerization solution. An apparatus 1 for removing residual monomers having a column main body and valve trays 2 having multiple gas blowout ports each having openings only in a direction perpendicular to the flow direction of the polymerization solution 4 or openings directed downward in the flow direction of the polymerization solution, which are installed in multiple stages in the column main body is used in a monomer-removing step of removing monomers in a polymerization solution 4 by bringing an organic solvent gas, such as methanol gas, into contact with a polymerization solution 4 obtained from a polymerization reactor 3.

摘要翻译： 本发明提供了除去残留单体的装置以及可以防止有机溶剂气体漂移和残留在托盘上的聚乙烯醇树脂的制造方法，能够有效地从聚合液中除去未反应的单体。 用于除去具有柱主体的残留单体和具有多个气体喷出口的阀塔盘2的设备1，每个气体喷出口仅在与聚合溶液4的流动方向垂直的方向上具有开口或者在聚合溶液的流动方向上向下指向的开口 在通过将甲醇气体等有机溶剂气体与聚合溶液4中得到的聚合溶液4接触的单体除去工序中，使用在柱主体中分段安装的单体除去工序 聚合反应器3。

公开(公告)号：US5575986A

公开(公告)日：1996-11-19

申请号：US423451

申请日：1995-04-19

申请人： Fumio Mori ,  Tadashi Okano ,  Kazuki Murakami ,  Masakazu Shintome ,  Hiromichi Mukai ,  Ikuko Miyagi ,  Takashi Imagawa ,  Sang-Won Kim ,  Taro Marukawa ,  Takahiro Kozuka

发明人： Fumio Mori ,  Tadashi Okano ,  Kazuki Murakami ,  Masakazu Shintome ,  Hiromichi Mukai ,  Ikuko Miyagi ,  Takashi Imagawa ,  Sang-Won Kim ,  Taro Marukawa ,  Takahiro Kozuka

IPC分类号： A61K49/06 ,  C07C229/16 ,  C07C237/04 ,  A61K49/00 ,  A61K31/295 ,  A61K31/32

CPC分类号： C07C229/16 ,  A61K49/06 ,  C07C237/04 ,  Y10T436/24

摘要： A compound of the following formula ##STR1## wherein m is an integer of 1 to 3, R.sub.1 and R.sub.2 are the same or different and each is hydrogen atom or lower alkyl, and R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are the same or different and each is hydroxy or a group of the formula ##STR2## (wherein n is 0 or 1, X is --NH-- or --O--, Y is alkylene, A is hydrogen atom, lower alkyl, lower alkoxy, halogen atom or trifluoromethyl, and B is alkyl or alkenyl), with the proviso that two or three of R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are hydroxyl groups and that when two of them are hydroxyl groups, the cases where R.sub.3 and R.sub.5 are hydroxy, and R.sub.4 and R.sub.6 are hydroxy are excluded; a complex compound comprising said compound and a metallic atom; and a diagnostic agent containing said complex compound. The above compound is useful as a chelating agent and the complex compound comprising said compound and a metallic atom exhibits superior characteristics as a contrast medium for image diagnosis.

摘要翻译： 下式的化合物，其中m为1〜3的整数，R 1和R 2相同或不同，各自为氢原子或低级烷基，R 3，R 4，R 5和R 6相同或不同， （其中n为0或1，X为-NH-或-O-，Y为亚烷基，A为氢原子，低级烷基，低级烷氧基，卤原子或三氟甲基） 并且B是烷基或烯基），条件是R3，R4，R5和R6中的两个或三个是羟基，当其中两个是羟基时，其中R3和R5是羟基，R4和R6是 羟基被排除; 包含所述化合物和金属原子的络合物; 和含有所述复合化合物的诊断剂。 上述化合物可用作螯合剂，并且包含所述化合物和金属原子的络合物表现出作为图像诊断的造影剂的优异特性。

公开(公告)号：US20120329950A1

公开(公告)日：2012-12-27

申请号：US13634331

申请日：2010-11-12

申请人： Takahiro Kozuka

发明人： Takahiro Kozuka

IPC分类号： C08F116/06 ,  B01J19/18

CPC分类号： C08F8/12 ,  C08F18/04

摘要： Provided is a method and an apparatus for producing a polyvinyl alcohol that can reduce energy consumption without deterioration in quality of the product polyvinyl alcohol. First, one or more vinyl esters are polymerized or a vinyl ester and other copolymerizable monomers are copolymerized to give a polyvinyl ester. Then, a raw saponification solution containing the polyvinyl ester and an organic solvent is fed through a channel 1 and a saponification catalyst-containing solution is introduced into the center of the channel. They are then mixed with static mixers 2 and the mixture 4 is subjected to saponification reaction, as it is placed on a belt 3.

摘要翻译： 提供一种可以降低能量消耗而不会使产品聚乙烯醇的质量下降的聚乙烯醇的制造方法和装置。 首先，聚合一种或多种乙烯基酯，或将乙烯基酯和其它可共聚单体共聚以得到聚乙烯酯。 然后，将含有聚乙烯基酯和有机溶剂的原始皂化溶液通过通道1进料，并将含皂化催化剂的溶液引入通道的中心。 然后将它们与静态混合器2混合，并将混合物4放置在带3上进行皂化反应。

公开(公告)号：US20130005905A1

公开(公告)日：2013-01-03

申请号：US13634313

申请日：2010-12-06

申请人： Takahiro Kozuka

发明人： Takahiro Kozuka

IPC分类号： C08F116/06 ,  B01J19/00

CPC分类号： C08F6/001 ,  B01J2208/00628 ,  B01J2219/00006 ,  C08F8/12 ,  C08L29/04 ,  C08F118/08

摘要： Provided are a method and an apparatus for producing a polyvinyl alcohol that can remove unreacted monomers from the polymerization solution efficiently and reduce the amount of methanol injected. A polymerization solution obtained by polymerization of one or more vinyl esters or copolymerization of a vinyl ester with other monomers copolymerizable therewith is adjusted to a particular concentration by addition of liquid methanol and then brought into contact with methanol vapor in counter-current flow for separation into a monomer-free polymer solution and a monomer/methanol mixture. The monomer-free polymer solution is then saponified in the presence of a catalyst to give a polyvinyl alcohol.

摘要翻译： 提供一种可以有效地从聚合溶液中除去未反应的单体的聚乙烯醇的制造方法和设备，并减少注入的甲醇的量。 通过一种或多种乙烯基酯的聚合或乙烯基酯与可与其共聚的其它单体的共聚得到的聚合溶液通过加入液态甲醇调节至特定的浓度，然后与逆流中的甲醇蒸气接触，分离成 无单体聚合物溶液和单体/甲醇混合物。 然后在催化剂存在下将无单体聚合物溶液皂化，得到聚乙烯醇。

公开(公告)号：US5453264A

公开(公告)日：1995-09-26

申请号：US204164

申请日：1994-03-03

申请人： Fumio Mori ,  Tadashi Okano ,  Kazuki Murakami ,  Masakazu Shintome ,  Hiromichi Mukai ,  Ikuko Miyagi ,  Takashi Imagawa ,  Sang-Won Kim ,  Taro Marukawa ,  Takahiro Kozuka

发明人： Fumio Mori ,  Tadashi Okano ,  Kazuki Murakami ,  Masakazu Shintome ,  Hiromichi Mukai ,  Ikuko Miyagi ,  Takashi Imagawa ,  Sang-Won Kim ,  Taro Marukawa ,  Takahiro Kozuka

IPC分类号： A61K49/06 ,  C07C229/16 ,  C07C237/04 ,  A61K49/00 ,  A61K31/295 ,  A61K31/32

CPC分类号： C07C229/16 ,  A61K49/06 ,  C07C237/04 ,  Y10T436/24

摘要： A compound of the following formula ##STR1## wherein m is an integer of 1 to 3, R.sub.1 and R.sub.2 are the same or different and each is hydrogen atom or lower alkyl, and R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are the same or different and each is hydroxy or a ##STR2## (wherein n is 0 or 1, X is --NH-- or --O--, Y is alkylene, A is hydrogen atom, lower alkyl, lower alkoxy, halogen atom or trifluoromethyl, and B is alkyl or alkenyl), with the proviso that two or three of R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are hydroxyl groups and that when two of them are hydroxyl groups, the cases where R.sub.3 and R.sub.5 are hydroxy, and R.sub.4 and R.sub.6 are hydroxy are excluded; a complex compound comprising said compound and a metallic atom; and a diagnostic agent containing said complex compound. The above compound is useful as a chelating agent and the complex compound comprising said compound and a metallic atom exhibits superior characteristics as a contrast medium for image diagnosis.

摘要翻译： 下式的化合物，其中m为1〜3的整数，R 1和R 2相同或不同，各自为氢原子或低级烷基，R 3，R 4，R 5和R 6相同或不同， （其中n为0或1，X为-NH-或-O-，Y为亚烷基，A为氢原子，低级烷基，低级烷氧基，卤素原子或三氟甲基，B为烷基 或烯基），条件是R3，R4，R5和R6中的两个或三个为羟基，当两个或三个为羟基时，排除R3和R5为羟基，R4和R6为羟基的情况; 包含所述化合物和金属原子的络合物; 和含有所述复合化合物的诊断剂。 上述化合物可用作螯合剂，并且包含所述化合物和金属原子的络合物表现出作为图像诊断的造影剂的优异特性。

公开(公告)号：US09022362B2

公开(公告)日：2015-05-05

申请号：US13634322

申请日：2010-12-06

申请人： Takahiro Kozuka

发明人： Takahiro Kozuka

IPC分类号： F02M29/04 ,  B01D3/34 ,  C08F6/00 ,  C08F216/06 ,  C08F118/08 ,  B01D3/22

CPC分类号： B01D3/343 ,  B01D3/22 ,  C08F6/003 ,  C08F8/12 ,  C08F118/08 ,  C08F216/06 ,  C08L29/04

摘要： Provided are an apparatus for removing residual monomers and a method of producing a polyvinyl alcohol resin that can prevent drift of the organic solvent gas and residual of the polymerization solution on the trays and permits efficient removal of the unreacted monomers from the polymerization solution. An apparatus 1 for removing residual monomers having a column main body and valve trays 2 having multiple gas blowout ports each having openings only in a direction perpendicular to the flow direction of the polymerization solution 4 or openings directed downward in the flow direction of the polymerization solution, which are installed in multiple stages in the column main body is used in a monomer-removing step of removing monomers in a polymerization solution 4 by bringing an organic solvent gas, such as methanol gas, into contact with a polymerization solution 4 obtained from a polymerization reactor 3.

摘要翻译： 本发明提供了除去残留单体的装置以及可以防止有机溶剂气体漂移和残留在托盘上的聚乙烯醇树脂的制造方法，能够有效地从聚合液中除去未反应的单体。 用于除去具有柱主体的残留单体和具有多个气体喷出口的阀塔盘2的设备1，每个气体喷出口仅在与聚合溶液4的流动方向垂直的方向上具有开口或者在聚合溶液的流动方向上向下指向的开口 在通过将甲醇气体等有机溶剂气体与聚合溶液4中得到的聚合溶液4接触的单体除去工序中，使用在柱主体中分段安装的单体除去工序 聚合反应器3。

公开(公告)号：US09074031B2

公开(公告)日：2015-07-07

申请号：US13581560

申请日：2010-11-12

申请人： Satoshi Watanabe ,  Takahiro Kozuka

发明人： Satoshi Watanabe ,  Takahiro Kozuka

IPC分类号： C08F8/00 ,  C08F16/06 ,  C08F216/06 ,  C08F6/00 ,  C08F6/06 ,  C08F6/16 ,  C08F6/28 ,  C08J11/02

CPC分类号： C08F216/06 ,  C08F6/003 ,  C08F6/008 ,  C08F6/06 ,  C08F6/16 ,  C08F6/28 ,  C08F8/12 ,  C08J11/02 ,  C08L29/04 ,  C08F118/08

摘要： Provided is a method of producing a polyvinyl alcohol resin, wherein the impurities in the resin are removed efficiently with a small amount of a washing liquid. A polyvinyl alcohol obtained after a polymerization step (step S1) and a saponification step (step S2) is washed with a washing liquid consisting of methyl acetate: 1 to 40 parts by mass, methanol: 50 to 98.9 parts by mass and water: 0.1 to 10 parts by mass in a washing step (step S3). The solid matter concentration of the slurry containing the washing liquid then is 1 to 30 mass %.

摘要翻译： 提供一种生产聚乙烯醇树脂的方法，其中用少量洗涤液有效地除去树脂中的杂质。 在聚合步骤（步骤S1）和皂化步骤（步骤S2）后获得的聚乙烯醇用乙酸甲酯洗涤液洗涤1至40质量份，甲醇：50至98.9质量份，水：0.1 在洗涤步骤中为10质量份（步骤S3）。 含有洗涤液的浆料的固体成分浓度为1〜30质量％。

公开(公告)号：US08816030B2

公开(公告)日：2014-08-26

申请号：US14114899

申请日：2012-02-07

申请人： Uichiro Yamagishi ,  Takashi Tachiyama ,  Takahiro Kozuka

发明人： Uichiro Yamagishi ,  Takashi Tachiyama ,  Takahiro Kozuka

IPC分类号： C08F236/18 ,  C08F2/22 ,  C08L11/00 ,  C08J3/24

CPC分类号： C08F236/18 ,  C08L11/00 ,  Y10T428/139 ,  C08F2/22

摘要： Provided are a chloroprene rubber, a chloroprene rubber composition and the vulcanizate and formed body thereof superior in low-temperature properties.A chloroprene rubber is obtained by emulsion polymerization of raw monomers containing antiperiplanar trans-1-chlorobuta-1,3-diene and cis-1-chlorobuta-1,3-diene in a total amount of 0.5 mass % or more, 2,3-dichlorobuta-1,3-diene in an amount of 2.0 mass % or more, and the rest being chloroprene. A composition containing the chloroprene is vulcanized into a formed body.

摘要翻译： 本发明提供氯丁橡胶，氯丁二烯橡胶组合物以及低温性优异的硫化橡胶及其成型体。 氯代丁二烯橡胶通过将含有反平面反式-1-氯代-1,3-二烯和顺式1-氯代-1,3-二烯的原料单体的总量为0.5质量％以上，2,3 二氯丁烷-1,3-二烯的量为2.0质量％以上，其余为氯丁二烯。 将含有氯丁二烯的组合物硫化成成型体。

公开(公告)号：US20120329949A1

公开(公告)日：2012-12-27

申请号：US13581560

申请日：2010-10-12

申请人： Satoshi Watanabe ,  Takahiro Kozuka

发明人： Satoshi Watanabe ,  Takahiro Kozuka

IPC分类号： C08F16/06

CPC分类号： C08F216/06 ,  C08F6/003 ,  C08F6/008 ,  C08F6/06 ,  C08F6/16 ,  C08F6/28 ,  C08F8/12 ,  C08J11/02 ,  C08L29/04 ,  C08F118/08

摘要： Provided is a method of producing a polyvinyl alcohol resin, wherein the impurities in the resin are removed efficiently with a small amount of a washing liquid.A polyvinyl alcohol obtained after a polymerization step (step S1) and a saponification step (step S2) is washed with a washing liquid consisting of methyl acetate: 1 to 40 parts by mass, methanol: 50 to 98.9 parts by mass and water: 0.1 to 10 parts by mass in a washing step (step S3). The solid matter concentration of the slurry containing the washing liquid then is 1 to 30 mass %.

摘要翻译： 提供一种生产聚乙烯醇树脂的方法，其中用少量洗涤液有效地除去树脂中的杂质。 在聚合步骤（步骤S1）和皂化步骤（步骤S2）后获得的聚乙烯醇用乙酸甲酯洗涤液洗涤1至40质量份，甲醇：50至98.9质量份，水：0.1 在洗涤步骤中为10质量份（步骤S3）。 含有洗涤液的浆料的固体成分浓度为1〜30质量％。