Nutrient infusion preparation
    1.
    发明授权
    Nutrient infusion preparation 失效
    营养输液制剂

    公开(公告)号:US06541029B1

    公开(公告)日:2003-04-01

    申请号:US09386518

    申请日:1999-08-31

    IPC分类号: A61K900

    CPC分类号: A61K9/0029

    摘要: A nutrient infusion preparation comprises a fat emulsion essentially consisting of fat particles having a mean particle size of 0.003 to 0.100 &mgr;m and a dispersion medium, and a solution containing electrolytes and amino acids. Also the nutrient infusion preparation comprises a fat emulsion (A) consisting essentially of fat particles having a mean particle size of 0.003 to 0.100 &mgr;m and a dispersion medium, and a solution (B) containing electrolytes and/or amino acids. A container having a plurality of chambers which are isolated from each other by partitions capable of being easily opened, whose respective chambers contain the fat emulsion (A) and said solution (B) and optionally a solution (C) containing saccharides. The infusion preparation of the present invention supplies various nutrient components including fatty acids required biologically to patients and enables amelioration or prevention of essential fatty acid deficiencies during TPN therapy. Further, the infusion preparation enables visual identification of insoluble foreign bodies present in an infusion container and can be administered to patients through a sterilization filter.

    摘要翻译: 营养液输注制剂包括基本上由平均粒径为0.003至0.100μm的脂肪颗粒和分散介质以及含有电解质和氨基酸的溶液组成的脂肪乳剂。 此外,营养液输液制剂包含基本上由平均粒径为0.003至0.100μm的脂肪颗粒和分散介质组成的脂肪乳液(A)和含有电解质和/或氨基酸的溶液(B)。 具有多个室的容器,其通过能容易地打开的隔板彼此隔开,其各室含有脂肪乳液(A)和所述溶液(B),并且任选地含有含有糖的溶液(C)。 本发明的输液制剂提供各种营养组分,包括生物需要的脂肪酸给患者,并且能够改善或预防TPN治疗期间必需脂肪酸缺乏。 此外,输液制剂能够目视识别存在于输液容器中的不溶性异物,并且可以通过灭菌过滤器向患者施用。

    Immunoglobulin/hydrophilic peptide complexes
    2.
    发明申请
    Immunoglobulin/hydrophilic peptide complexes 审中-公开
    免疫球蛋白/亲水肽复合物

    公开(公告)号:US20060233790A1

    公开(公告)日:2006-10-19

    申请号:US10504520

    申请日:2003-03-19

    IPC分类号: A61K39/395

    摘要: The present invention provides an immunoglobulin preparation comprising an immunoglobulin-hydrophilic peptide complex in which an immunoglobulin and a hydrophilic peptide are linked optionally via a divalent group, and a pharmacologically acceptable carrier. The immunoglobulin preparation has cell permeability, or in other words, it can penetrate through a cell membrane and attain inside.

    摘要翻译: 本发明提供了一种免疫球蛋白制剂,其包含免疫球蛋白亲水性肽复合物,其中免疫球蛋白和亲水性肽可任意地通过二价基团连接,以及药理学上可接受的载体。 免疫球蛋白制剂具有细胞渗透性,或者换句话说,其可以穿透细胞膜并达到内部。