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1.发明申请公开(公告)号：US20080312470A1
公开(公告)日：2008-12-18
申请号：US12197401
申请日：2008-08-25
IPC分类号： C07C237/26 , C07C225/20
CPC分类号： C07C49/835 , C07C225/20 , C07C237/24 , C07C2601/16 , C07C2602/28 , C07C2603/24
摘要： The present invention is directed to novel compounds which are derivatives of minocycline or doxycycline, pharmaceutical compositions containing same and use thereof in lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic.
摘要翻译： 本发明涉及作为二甲胺四环素或多西环素的衍生物的新化合物，含有它们的药物组合物及其在降低IgE致病性疾病的哺乳动物中降低过量IgE水平的用途。
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2.发明授权公开(公告)号：US07649113B2
公开(公告)日：2010-01-19
申请号：US12197401
申请日：2008-08-25
IPC分类号： C07C233/00
CPC分类号： C07C49/835 , C07C225/20 , C07C237/24 , C07C2601/16 , C07C2602/28 , C07C2603/24
摘要： The present invention is directed to novel compounds which are derivatives of minocycline or doxycycline, pharmaceutical compositions containing same and use thereof in lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic.
摘要翻译： 本发明涉及作为二甲胺四环素或多西环素的衍生物的新化合物，含有它们的药物组合物及其在降低IgE致病性疾病的哺乳动物中降低过量IgE水平的用途。
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公开(公告)号：US07425655B2
公开(公告)日：2008-09-16
申请号：US10544814
申请日：2004-02-09
CPC分类号： C07C49/835 , C07C225/20 , C07C237/24 , C07C2601/16 , C07C2602/28 , C07C2603/24
摘要： The present invention is directed novel compounds which are derivatives of minocycline or doxycycline, pharmaceutical compositions containing same and use thereof in lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic.
摘要翻译： 本发明涉及作为二甲胺四环素或多西环素的衍生物的新型化合物，含有它们的药物组合物及其在降低IgE致病性疾病的哺乳动物中降低过量IgE水平的用途。
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