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    Servo control circuit for detecting analytes via nanoparticle-labeled substances with electromagnetic read-write heads
    2.
    发明授权
    Servo control circuit for detecting analytes via nanoparticle-labeled substances with electromagnetic read-write heads 有权
    用于通过具有电磁读写头的纳米颗粒标记物质检测分析物的伺服控制电路

    公开(公告)号：US08694280B2

    公开(公告)日：2014-04-08

    申请号：US12888403

    申请日：2010-09-22

    申请人： Tara L. Awezec ,  Dylan Joseph Boday ,  Stephen Leonard Schwartz ,  Anna W. Topol ,  Daniel James Winarski

    发明人： Tara L. Awezec ,  Dylan Joseph Boday ,  Stephen Leonard Schwartz ,  Anna W. Topol ,  Daniel James Winarski

    IPC分类号： G01C9/00

    CPC分类号： G01N33/54346 ,  B82Y15/00 ,  G01N33/54326 ,  G01N33/54333

    摘要： A circuit for controlling an electromagnetic head module to detect antigens on a biosample track comprising a processor for receiving position-error-servo signal from the PES read sensor, a write head for magnetizing nanoparticles attached to antigens, and a read sensor for detecting the nanoparticle-labeled antigens. The circuit may further comprise an X-axis actuator for controlling the head module in the direction perpendicular to the track and an Y-axis actuator coupled to the head module and the X-axis actuator for controlling the head module in the direction of the track. Target antigens are attached to the biosample track and nanoparticles via antibodies.

    摘要翻译： 一种用于控制电磁头模块以检测生物样本轨道上的抗原的电路，包括用于从PES读取传感器接收位置误差伺服信号的处理器，用于磁化附着于抗原的纳米颗粒的写入头和用于检测纳米颗粒的读取传感器 标记的抗原。 电路还可以包括用于在垂直于轨道的方向上控制头模块的X轴致动器，以及耦合到头模块的Y轴致动器和用于在轨道方向上控制头模块的X轴致动器 。 靶抗原通过抗体连接到生物样品轨道和纳米颗粒上。

    READ-AFTER-WRITE DETECTION OF ANALYTES VIA NANOPARTICLE-LABELED SUBSTANCES
    3.
    发明申请
    READ-AFTER-WRITE DETECTION OF ANALYTES VIA NANOPARTICLE-LABELED SUBSTANCES 审中-公开
    通过纳米材料标签物质的分析仪的后读写检测

    公开(公告)号：US20110076782A1

    公开(公告)日：2011-03-31

    申请号：US12888394

    申请日：2010-09-22

    申请人： Tara L. Awezec ,  Dylan Joseph Boday ,  Lee Curtis Randall ,  Stephen Leonard Schwartz ,  Anna W. Topol ,  Daniel James Winarski

    发明人： Tara L. Awezec ,  Dylan Joseph Boday ,  Lee Curtis Randall ,  Stephen Leonard Schwartz ,  Anna W. Topol ,  Daniel James Winarski

    IPC分类号： G01N33/53 ,  B01J19/00

    CPC分类号： G01N33/54346 ,  B82Y15/00 ,  G01N33/54326 ,  G01N33/54333

    摘要： Embodiments of the invention relate to magnetizing and detecting nanoparticle-labeled antigens on biosample tracks deposited on a tape media. An aspect of the invention comprises apparatus and methods for labeling antigens with demagnetized nanoparticles, magnetizing the nanoparticles with an electromagnetic write head, and detecting the antigens via the magnetized nanoparticles by reading the tape media with a read sensor in a read-after-write operation. The write head and read sensor are part of a head-module of magnetic tape drive. Target antigens are attached to the biosample tracks by antibodies. Nanoparticles of differing magnetic properties may be selectively paired with antibodies associated with different antigens to allow multiple antigens to be detected upon a single scan by the read sensor.

    摘要翻译： 本发明的实施方案涉及在沉积在带介质上的生物样品轨道上磁化和检测纳米颗粒标记的抗原。 本发明的一个方面包括用去磁纳米颗粒标记抗原的装置和方法，用电磁写头磁化纳米颗粒，并通过在读写操作中用读取传感器读取磁带介质，通过磁化纳米颗粒检测抗原 。 写头和读取传感器是磁带驱动器的头模块的一部分。 靶抗原通过抗体连接到生物样品轨道上。 具有不同磁性的纳米颗粒可以与与不同抗原相关的抗体选择性配对，以允许通过读取传感器进行单次扫描来检测多个抗原。