公开(公告)号：US20210177896A1

公开(公告)日：2021-06-17

申请号：US16305728

申请日：2017-06-02

申请人： David L. Porter ,  Noelle Frey ,  Carl H. June ,  Simon Lacey ,  Fang Chen ,  Jan J. Melenhorst ,  Tetiana Taran ,  Karen Thudium Mueller ,  Patricia Wood ,  Yiyun Zhang ,  Novartis AG ,  The Trustees of the University of Pennsylvania

发明人： David L. Porter ,  Noelle Frey ,  Carl H. June ,  Simon Lacey ,  Fang Chen ,  Jan J. Melenhorst ,  Tetiana Taran ,  Karen Thudium Mueller ,  Patricia Wood ,  Yiyun Zhang

IPC分类号： A61K35/17 ,  A61P35/00 ,  C07K14/705 ,  G01N33/50 ,  G01N33/68 ,  C07K16/28

摘要： The invention provides a method of treating an adult subject having a hematological cancer, comprising administering to the subject selected dosage regimens comprising a plurality of immune effector cells expressing a CAR molecule.