公开(公告)号：US20200078495A1

公开(公告)日：2020-03-12

申请号：US15746141

申请日：2016-07-20

申请人： Tufts University ,  Massachusetts Eye and Ear Infirmary ,  The General Hospital Corporation - dba Mass General Hospital

发明人： David Kaplan ,  Michael Whalen ,  Christopher Hartnick

IPC分类号： A61L29/14 ,  A61F11/00 ,  A61L29/04 ,  A61L29/16

摘要： In some embodiments, the present invention provides methods for making resorbable ear tubes including the steps of providing a silk fibroin solution, and forming a silk ear tube from the silk fibroin solution, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbable. In some embodiments, the present invention also provides methods for treating otitis media including the step of introducing a silk ear tube into the ear canal of a subject, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbed by the subject.