公开(公告)号：US20120264775A1

公开(公告)日：2012-10-18

申请号：US13426521

申请日：2012-03-21

申请人： Jennifer Riggs-Sauthier ,  Bo-Liang Deng ,  Timoty A. Riley

发明人： Jennifer Riggs-Sauthier ,  Bo-Liang Deng ,  Timoty A. Riley

IPC分类号： C07D489/08 ,  A61P25/00 ,  A61K31/485

CPC分类号： A61K31/485 ,  A61K31/402 ,  A61K31/4025 ,  A61K31/439 ,  A61K31/4468 ,  A61K47/10 ,  A61K47/60 ,  C07D489/02

摘要： The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.