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1.发明申请Method of Cultivating Fermentative Yeast Used for Xylose Fermentation of Non-Detoxified Lignocellulosic Hydrolysate 审中-公开培养用于非脱毒木质纤维素水解产物的木糖发酵的发酵酵母的方法公开(公告)号：US20110177572A1
公开(公告)日：2011-07-21
申请号：US12689809
申请日：2010-01-19
Applicant: Jia-Baau Wang , Lee-Chung Men , Wen-Song Hwang , Wen-Hua Chen , Sheng-Shieh Chen , Wen-Heng Chen , Ting-Hsiang Lin , Chiung-Fang Huang , Sheng-Hsin Chou , Teng-Chieh Hsu , Gia-Luen Guo
Inventor： Jia-Baau Wang , Lee-Chung Men , Wen-Song Hwang , Wen-Hua Chen , Sheng-Shieh Chen , Wen-Heng Chen , Ting-Hsiang Lin , Chiung-Fang Huang , Sheng-Hsin Chou , Teng-Chieh Hsu , Gia-Luen Guo
Abstract: A hydrolysate-adapted yeast, Pichia stipitis INER 1128, is cultivated according to the present invention. The adapted yeast can effectively convert xylose into ethanol in lignocellulosic hydrolysate, which is not even detoxified. Well ethanol yield is obtained while xylose is not wasted and thus cost is reduced.
Abstract translation: 根据本发明培养水解产物适应酵母毕赤酵母INER 1128。 木质纤维素水解物中的适应酵母可以有效地将木糖转化为乙醇，甚至不能解毒。 获得良好的乙醇产率，而木糖不被浪费，因此成本降低。
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2.发明申请Method of Xylose Fermentation Having Enhanced Conversion Rate in Fiber Solution 审中-公开在纤维素溶液中增加转化率的木糖发酵方法公开(公告)号：US20110097780A1
公开(公告)日：2011-04-28
申请号：US12822274
申请日：2010-06-24
Applicant: Ting-Hsiang Lin , Chiung-Fang Huang , Gia-Luen Guo , Wen-Song Hwang
Inventor： Ting-Hsiang Lin , Chiung-Fang Huang , Gia-Luen Guo , Wen-Song Hwang
IPC: C12P7/10
Abstract: A method is provided for improving the efficiency of xylose fermentation in lignocellulosic hydrolysate. The disclosed embodiment raises the efficiency of xylose conversion by adding a specific lignocellulosic material during fermentation. In particular, a 10% enhancement in the efficiency of xylose conversion for ethanol production was given, and the ethanol yield is achieved 90% after adding the specific lignocellulosic material.
Abstract translation: 提供了一种提高木质纤维素水解产物中木糖发酵效率的方法。 所公开的实施方案通过在发酵过程中加入特定的木质纤维素材料提高了木糖转化的效率。 特别地，提供了用于乙醇生产的木糖转化效率的10％提高，并且在加入特定的木质纤维素材料后，乙醇产率达到了90％。
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公开(公告)号：US08603776B2
公开(公告)日：2013-12-10
申请号：US13242547
申请日：2011-09-23
Applicant: Tien-Yang Ma , Ting-Hsiang Lin , Teng-Chieh Hsu , Chiung-Fang Huang , Gia-Leun Guo , Wen-Song Hwang , Jia-Baau Wang , Yun-Peng Chao , Guan-Lin Yeh
Inventor： Tien-Yang Ma , Ting-Hsiang Lin , Teng-Chieh Hsu , Chiung-Fang Huang , Gia-Leun Guo , Wen-Song Hwang , Jia-Baau Wang , Yun-Peng Chao , Guan-Lin Yeh
IPC: C12P21/06
CPC classification number: C12N9/0006 , C12N9/1205 , C12P7/10 , Y02E50/16
Abstract: A method for preparing a xylose-utilizing strain of Saccharomyces cerevisiae and the Saccharomyces cerevisiae are introduced. The preferred recombinant strain contains multiple copies of integrated xylose metabolic genes, and can rapidly ferment xylose to produce ethanol from synthetic medium and lignocellulosic raw materials. The xylose-utilizing strain is applicable for the cellulosic ethanol production industry and brewing industry.
Abstract translation: 引入了一种用于制备酿酒酵母和酿酒酵母的木糖利用菌株的方法。 优选的重组菌株含有多个拷贝的综合木糖代谢基因，可以快速发酵木糖，从合成培养基和木质纤维素原料中生产乙醇。 木糖利用菌株适用于纤维素乙醇生产工业和酿造工业。
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4.发明申请Method to Increase the Ethanol Concentration from the Conversion of Lignocellulose 审中-公开从木质纤维素转化中提高乙醇浓度的方法公开(公告)号：US20110104775A1
公开(公告)日：2011-05-05
申请号：US12856073
申请日：2010-08-13
Applicant: Teng-Chieh Hsu , Ting-Hsiang Lin , Tien-Yang Ma , Gia-Luen Guo , Wen-Song Hwang , Jia-Baau Wang
Inventor： Teng-Chieh Hsu , Ting-Hsiang Lin , Tien-Yang Ma , Gia-Luen Guo , Wen-Song Hwang , Jia-Baau Wang
IPC: C12P7/10
Abstract: The present disclosure is related to a method for increasing the ethanol concentration from the conversion of lignocellulose. The pretreated solid residues are mixed with ethanol-containing broth from the fermentation of xylose hydrolysate by Pichia stipitis and then are performed under the process of simultaneous saccharification and fermentation (SSF) with Sacharomyces cerevisiae and cellulase for converting cellulose to ethanol. The final ethanol concentration in broth as well as the ethanol productivity is increased at least 1.8 times in comparison of conventional process for lignocellulosic ethanol production.
Abstract translation: 本公开涉及一种从木质纤维素转化中提高乙醇浓度的方法。 将经预处理的固体残余物与乙醇培养液混合，通过树干毕赤酵母发酵木糖水解产物，然后在与酿酒酵母和纤维素酶同时糖化和发酵（SSF）的过程中进行纤维素转化为乙醇。 与木质纤维素乙醇生产的常规方法相比，肉汤中的最终乙醇浓度以及乙醇生产率提高至少1.8倍。
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公开(公告)号：US20120309093A1
公开(公告)日：2012-12-06
申请号：US13242547
申请日：2011-09-23
Applicant: Tien-Yang Ma , Ting-Hsiang Lin , Teng-Chieh Hsu , Chiung-Fang Huang , Gia-Leun Guo , Wen-Song Hwang , Jia-Baau Wang , Yun-Peng Chao , Guan-Lin Yeh
Inventor： Tien-Yang Ma , Ting-Hsiang Lin , Teng-Chieh Hsu , Chiung-Fang Huang , Gia-Leun Guo , Wen-Song Hwang , Jia-Baau Wang , Yun-Peng Chao , Guan-Lin Yeh
IPC: C12N15/81
CPC classification number: C12N9/0006 , C12N9/1205 , C12P7/10 , Y02E50/16
Abstract: A method for preparing a xylose-utilizing strain of Saccharomyces cerevisiae and the Saccharomyces cerevisiae are introduced. The preferred recombinant strain contains multiple copies of integrated xylose metabolic genes, and can rapidly ferment xylose to produce ethanol from synthetic medium and lignocellulosic raw materials. The xylose-utilizing strain is applicable for the cellulosic ethanol production industry and brewing industry.
Abstract translation: 引入了一种用于制备酿酒酵母和酿酒酵母的木糖利用菌株的方法。 优选的重组菌株含有多个拷贝的综合木糖代谢基因，可以快速发酵木糖，从合成培养基和木质纤维素原料中生产乙醇。 木糖利用菌株适用于纤维素乙醇生产工业和酿造工业。
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Patent Agency Ranking
公开(公告)号：US08278078B2
公开(公告)日：2012-10-02
申请号：US12790484
申请日：2010-05-28
Applicant: Chiung-Fang Huang , Wei-Hsi Chen , Ting-Hsiang Lin , Wen-Heng Chen , Gia-Luen Guo , Wen-Song Hwang
Inventor： Chiung-Fang Huang , Wei-Hsi Chen , Ting-Hsiang Lin , Wen-Heng Chen , Gia-Luen Guo , Wen-Song Hwang
CPC classification number: C12P7/18 , C12N1/16 , C12N1/36 , C12P2203/00
Abstract: A method for culturing the yeast for enhancing pentitol production is provided. The yeast cultured according to the present disclosure is Pichia stipitis. Application of the yeast in pentitol production by fermention of the lignocellulosic hydrolysate or the xylose-to-pentitol production yield can be enhanced 3 to 6 times from the non-detoxified or the overliming-processed lignocellulosic hydrolysate.
Abstract translation: 提供了一种用于培养用于增强戊糖醇生产的酵母的方法。 根据本公开培养的酵母是毕赤酵母属。 通过发酵木质纤维素水解产物或木糖至戊糖醇生产产率的酵母在戊糖醇生产中的应用可以从未解毒或经过加工的木质纤维素水解产物提高3至6倍。
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公开(公告)号：US20110104772A1
公开(公告)日：2011-05-05
申请号：US12790484
申请日：2010-05-28
Applicant: Chiung-Fang Huang , Wei-Hsi Chen , Ting-Hsiang Lin , Wen-Heng Chen , Gia-Luen Guo , Wen-Song Hwang
Inventor： Chiung-Fang Huang , Wei-Hsi Chen , Ting-Hsiang Lin , Wen-Heng Chen , Gia-Luen Guo , Wen-Song Hwang
IPC: C12P7/18
CPC classification number: C12P7/18 , C12N1/16 , C12N1/36 , C12P2203/00
Abstract: A method for culturing the yeast for enhancing pentitol production is provided. The yeast cultured according to the present disclosure is Pichia stipitis. Application of the yeast in pentitol production by fermention of the lignocellulosic hydrolysate or the xylose-to-pentitol production yield can be enhanced 3 to 6 times from the non-detoxified or the overliming-processed lignocellulosic hydrolysate
Abstract translation: 提供了一种用于培养用于增强戊糖醇生产的酵母的方法。 根据本公开培养的酵母是毕赤酵母属。 通过发酵木质纤维素水解产物或木糖至戊糖醇生产产率的酵母在戊糖醇生产中的应用可以从非解毒或加工过的木质纤维素水解产物中提高3至6倍
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8.发明申请METHOD FOR PRODUCING XYLITOL FROM LIGNOCELLULOSIC HYDROLYSATES WITHOUT DETOXIFICATION 有权在没有脱氧作用的情况下从水杨酸水解产物生产XYLITOL的方法公开(公告)号：US20110097772A1
公开(公告)日：2011-04-28
申请号：US12775655
申请日：2010-05-07
Applicant: Chiung-Fang Huang , Yi-Feng Jiang , Ting-Hsiang Lin , Gia-Luen Guo , Wen-Song Hwang , Jia-Baau Wang
Inventor： Chiung-Fang Huang , Yi-Feng Jiang , Ting-Hsiang Lin , Gia-Luen Guo , Wen-Song Hwang , Jia-Baau Wang
IPC: C12P7/18
CPC classification number: C12P7/18
Abstract: A method for producing xylitol by fermentation of lignocellulosic hydrolysates without detoxification is provided. By using the originally isolated yeast Candida sp., xylose can be effectively converted into xylitol. The invention also provides the Candida strain having high furfural tolerance, and is capable to produce xylitol from various types of non-detoxified lignocellulosic hydrolysates, in which the overall utilization of xylose in hydrolysate can reach over 95%.
Abstract translation: 提供了一种通过发酵木质纤维素水解产物而无需解毒来生产木糖醇的方法。 通过使用最初分离的酵母假丝酵母属，木糖可以有效转化成木糖醇。 本发明还提供了具有高糠醛耐性的假丝酵母菌株，并且能够从各种类型的非解毒木质纤维素水解产物中产生木糖醇，其中水解产物中木糖的总体利用可以达到95％以上。
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公开(公告)号：US20060057161A1
公开(公告)日：2006-03-16
申请号：US10942698
申请日：2004-09-16
Applicant: Chang-Jen Huang , Yueh-Chun Hsieh , Chih-Ming Chou , Ho-Sheng Wu , Ting-Hsiang Lin
Inventor： Chang-Jen Huang , Yueh-Chun Hsieh , Chih-Ming Chou , Ho-Sheng Wu , Ting-Hsiang Lin
CPC classification number: C07K14/005 , C12N2770/20022 , G01N2333/165 , G01N2469/20
Abstract: Isolated polypeptides containing one of SEQ ID NOs: 1-11. Also disclosed are (i) isolated nucleic acids encoding the polypeptides and related expression vectors and host cells; (ii) purified antibodies that recognize the polypeptides; and (iii) methods of producing the polypeptides, diagnosing infection with a coronavirus, and producing the antibodies.
Abstract translation: 含有SEQ ID NO：1-11之一的分离的多肽。 还公开了（i）编码多肽和相关表达载体和宿主细胞的分离的核酸; （ii）识别多肽的纯化抗体; 和（iii）产生多肽的方法，诊断冠状病毒的感染和产生抗体。
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10.发明授权Method for producing xylitol from lignocellulosic hydrolysates without detoxification 有权从没有解毒的木质纤维素水解产物生产木糖醇的方法公开(公告)号：US08409835B2
公开(公告)日：2013-04-02
申请号：US12775655
申请日：2010-05-07
Applicant: Chiung-Fang Huang , Yi-Feng Jiang , Ting-Hsiang Lin , Gia-Luen Guo , Wen-Song Hwang , Jia-Baau Wang
Inventor： Chiung-Fang Huang , Yi-Feng Jiang , Ting-Hsiang Lin , Gia-Luen Guo , Wen-Song Hwang , Jia-Baau Wang
CPC classification number: C12P7/18
Abstract: A method for producing xylitol by fermentation of lignocellulosic hydrolysates without detoxification is provided. By using the originally isolated yeast Candida sp., xylose can be effectively converted into xylitol. The invention also provides the Candida strain having high furfural tolerance, and is capable to produce xylitol from various types of non-detoxified lignocellulosic hydrolysates, in which the overall utilization of xylose in hydrolysate can reach over 95%.
Abstract translation: 提供了一种通过发酵木质纤维素水解产物而无需解毒来生产木糖醇的方法。 通过使用最初分离的酵母假丝酵母属，木糖可以有效转化成木糖醇。 本发明还提供了具有高糠醛耐性的假丝酵母菌株，并且能够从各种类型的非解毒木质纤维素水解产物中产生木糖醇，其中水解产物中木糖的总体利用可以达到95％以上。
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