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公开(公告)号:US20090311226A1
公开(公告)日:2009-12-17
申请号:US12300685
申请日:2007-05-22
申请人: John W. Harmon , Guy Pierre Marti , Tomoharu Miyashita , Michael Gibson , Todd Armstrong , Pramod Bonde
发明人: John W. Harmon , Guy Pierre Marti , Tomoharu Miyashita , Michael Gibson , Todd Armstrong , Pramod Bonde
CPC分类号: A61K39/0011 , A61K2039/5152 , A61K2039/5156 , A61K2039/55522
摘要: Enhancing the immune response to esophageal tumor cells reduces the incidence of esophageal cancer developing, recurring, or metastasizing. Esophageal cancer cells are modified to render them more immunogenic and proliferation compromised. They are used in an antigenic preparation to raise a T cell response in the recipient.
摘要翻译: 增强对食管肿瘤细胞的免疫反应降低食管癌发生,复发或转移的发生率。 食管癌细胞被修饰以使其更具免疫原性和增殖受损。 它们用于抗原制剂以提高受体中的T细胞应答。