Oral cavity disintegrating tablet and method of producing the same
    2.
    发明授权
    Oral cavity disintegrating tablet and method of producing the same 有权
    口腔崩解片及其制造方法

    公开(公告)号:US09314454B2

    公开(公告)日:2016-04-19

    申请号:US12810779

    申请日:2008-12-26

    摘要: The invention provides an orally disintegrating tablet containing (a) one or more saccharides or sugar alcohols selected from the group consisting of mannitol, lactose, xylitol, sucrose, erythritol and glucose and (b) low substituted hydroxypropylcellulose and substantially free of a starch disintegrant, which tablet is produced by steps of granulating a composition containing the above-mentioned components (a) and (b) by an agitation granulation method, and compression-molding the obtained granulation product. The invention also provides a method of producing an orally disintegrating tablet substantially free of a starch disintegrant, including steps of granulating a composition containing the above-mentioned components by an agitation granulation method, and compression-molding the obtained granulation product.

    摘要翻译: 本发明提供一种口服崩解片,其含有(a)一种或多种选自甘露醇,乳糖,木糖醇,蔗糖,赤藓醇和葡萄糖的糖或糖醇,和(b)低取代羟丙基纤维素,基本上不含淀粉崩解剂, 通过使用搅拌造粒法将含有上述成分(a)和(b)的组合物成粒的工序来制造该片剂,并对得到的造粒物进行压缩成型。 本发明还提供一种生产基本上不含淀粉崩解剂的口腔崩解片剂的方法,包括通过搅拌造粒法造粒含有上述组分的组合物,并将所得制粒产品压缩成型的步骤。

    ORAL CAVITY DISINTEGRATING TABLET AND METHOD OF PRODUCING THE SAME
    4.
    发明申请
    ORAL CAVITY DISINTEGRATING TABLET AND METHOD OF PRODUCING THE SAME 有权
    口腔消毒片及其制造方法

    公开(公告)号:US20100278930A1

    公开(公告)日:2010-11-04

    申请号:US12810779

    申请日:2008-12-26

    IPC分类号: A61K9/14 A61K47/38

    摘要: The invention provides an orally disintegrating tablet containing (a) one or more saccharides or sugar alcohols selected from the group consisting of mannitol, lactose, xylitol, sucrose, erythritol and glucose and (b) low substituted hydroxypropylcellulose and substantially free of a starch disintegrant, which tablet is produced by steps of granulating a composition containing the above-mentioned components (a) and (b) by an agitation granulation method, and compression-molding the obtained granulation product. The invention also provides a method of producing an orally disintegrating tablet substantially free of a starch disintegrant, including steps of granulating a composition containing the above-mentioned components by an agitation granulation method, and compression-molding the obtained granulation product.

    摘要翻译: 本发明提供一种口服崩解片,其含有(a)一种或多种选自甘露醇,乳糖,木糖醇,蔗糖,赤藓醇和葡萄糖的糖或糖醇,和(b)低取代羟丙基纤维素,基本上不含淀粉崩解剂, 通过使用搅拌造粒法将含有上述成分(a)和(b)的组合物成粒的工序来制造该片剂,并对得到的造粒物进行压缩成型。 本发明还提供一种生产基本上不含淀粉崩解剂的口腔崩解片剂的方法,包括通过搅拌造粒法造粒含有上述组分的组合物,并将所得制粒产品压缩成型的步骤。