公开(公告)号：US07090802B1

公开(公告)日：2006-08-15

申请号：US10348621

申请日：2003-01-29

申请人： Kai Wang ,  Tong-Yuan Kuo ,  Li-Chuan Chien

发明人： Kai Wang ,  Tong-Yuan Kuo ,  Li-Chuan Chien

IPC分类号： G01N31/22

CPC分类号： B01L3/5023 ,  B01L2300/0825 ,  B01L2300/0864 ,  G01N33/525 ,  G01N33/54386 ,  G01N33/558 ,  G01N33/74 ,  G01N33/76 ,  G01N2500/20

摘要： A sampling assembly for simultaneously testing a liquid biological sample for a plurality of hormones and method thereof are described. A sampling membrane includes a dry porous carrier having a proximal end narrower than a distal end and forming a unidirectional liquid flow channel. The distal end includes a plurality of tines arranged and separated by substantially regular spacing. Each tine defines a dye zone including a dye-tagged antigen-specific antibody at a distal end. The sampling membrane further defines a set of focusing recesses along each side of the unidirectional flow channel end and a set of dispersal recesses between and adjacent to each tine. A plurality of test strips each include a dry porous carrier communicatively attached to the distal end of one such tine. Each test strip forms a unidirectional liquid flow channel and includes a testing zone comprising an antigen-specific antibody located distally from the dye zone.

摘要翻译： 描述了用于同时测试多种激素的液体生物样品的取样组件及其方法。 采样膜包括具有比远端更窄的近端并形成单向液体流动通道的干燥多孔载体。 远端包括以基本上规则的间隔布置和分开的多个齿。 每个齿在远端限定包括染料标记的抗原特异性抗体的染色区。 采样膜进一步限定沿着单向流动通道端的每一侧的一组聚焦凹槽以及在每个齿之间和之间相邻的一组分散凹槽。 多个测试条各自包括通信地连接到一个这样的齿的远端的干燥多孔载体。 每个测试条形成单向液体流动通道并且包括包含位于远离染料区的抗原特异性抗体的测试区。