公开(公告)号：US06258591B1

公开(公告)日：2001-07-10

申请号：US09194779

申请日：1998-12-03

申请人： Toyoaki Yoneda ,  Takashi Fujii ,  Mika Morita ,  Takeshi Ohnuma ,  Hiroshi Tanouchi ,  Shigeru Nakamura

发明人： Toyoaki Yoneda ,  Takashi Fujii ,  Mika Morita ,  Takeshi Ohnuma ,  Hiroshi Tanouchi ,  Shigeru Nakamura

IPC分类号： C12S900

CPC分类号： C11D3/485 ,  A61L12/082 ,  A61L12/105 ,  C11D3/0042 ,  C11D3/0078 ,  C11D3/222 ,  C11D3/38618 ,  Y10S134/901 ,  Y10S514/84

摘要： The present invention provides a combined formulation for disinfecting, neutralizing and cleaning a soft contact lens and a method using the same easily, efficiently and safely. The formulation is a one-solution type of combined formulation for disinfecting, neutralizing and cleaning a soft contact lens, which includes a first formulation that contains an iodine-based disinfectant and a proteolytic enzyme and a second formulation that contains a reducing and a foaming agent treated with a delayed release coating, and which contains a nonionic surfactant in at least one of the first and second formulations. A stained soft contact lens can be disinfected, neutralized and cleaned easily by holding it in an aqueous solution colored yellow or brown by iodine molecules and removing it from the aqueous solution after the solution becomes almost colorless.

摘要翻译： 本发明提供了一种用于消毒，中和和清洁软性隐形眼镜的组合制剂，以及使用该隐形眼镜的方法。 该制剂是用于消毒，中和和清洁软性隐形眼镜的单一溶液型组合制剂，其包括含有碘基消毒剂和蛋白水解酶的第一制剂和含有还原剂和发泡剂的第二制剂 用延迟释放涂层处理，并且在第一和第二配方中的至少一种中含有非离子表面活性剂。 染色的软性隐形眼镜可以通过将其保持在由碘分子着色为黄色或棕色的水溶液中而容易地消毒，中和和清洁，并且在溶液变得几乎无色后将其从水溶液中除去。

公开(公告)号：US20100056631A1

公开(公告)日：2010-03-04

申请号：US12447413

申请日：2007-10-26

申请人： Ryuji Hisamura ,  Shigeru Nakamura ,  Toyoaki Yoneda

发明人： Ryuji Hisamura ,  Shigeru Nakamura ,  Toyoaki Yoneda

IPC分类号： A61K31/19 ,  C07C59/01 ,  A61P27/14

CPC分类号： A61K31/191 ,  A61K9/0048 ,  A61K31/19 ,  A61K49/0008

摘要： An antiallergenic composition comprising 3-hydroxybutyric acid and/or a salt thereof. The antiallergenic composition is safe.

摘要翻译： 包含3-羟基丁酸和/或其盐的抗过敏组合物。 抗过敏组合物安全。

公开(公告)号：US4024223A

公开(公告)日：1977-05-17

申请号：US570429

申请日：1975-04-22

申请人： Kanji Noda ,  Kazuki Furuya ,  Satoru Miyata ,  Toyoaki Yoneda

发明人： Kanji Noda ,  Kazuki Furuya ,  Satoru Miyata ,  Toyoaki Yoneda

IPC分类号： A61K9/70 ,  C08B37/00 ,  A61K31/70

CPC分类号： B82Y5/00 ,  A61K9/70 ,  C08B37/0015

摘要： A stupe composition comprising a stupe base and an antiphlogistic and analgetic medicine, said medicine containing an interacted compound selected from the group consisting of an interacted compound of menthol and a cyclodextrin and an interacted compound of methyl salicylate and a cyclodextrin. The said composition is prepared by uniformly mixing a stupe base and the interacted compound.

摘要翻译： 一种包含愚昧碱和消炎药和止痛药的愚昧组合物，所述药物含有选自由薄荷醇和环糊精相互作用的化合物和水杨酸甲酯与环糊精相互作用的化合物组成的组的相互作用化合物。 所述组合物通过均匀混合愚蠢碱和相互作用的化合物来制备。

公开(公告)号：US06495598B1

公开(公告)日：2002-12-17

申请号：US09807739

申请日：2001-04-18

申请人： Toyoaki Yoneda ,  Nobuhisa Naoi ,  Hiroaki Miichi ,  Shigeru Nakamura ,  Toshinao Hata ,  Fumio Saito ,  Takeshi Ohnuma

发明人： Toyoaki Yoneda ,  Nobuhisa Naoi ,  Hiroaki Miichi ,  Shigeru Nakamura ,  Toshinao Hata ,  Fumio Saito ,  Takeshi Ohnuma

IPC分类号： A61K3122

CPC分类号： A61K9/0048 ,  Y10S514/912

摘要： A one-pack preparation of irrigating solution for ocular surgery of cataract, glaucoma or intraocular lens transplantation, which is excellent in the protection of ophthalmic tissues and endothelial cells during and after the operation and has a high in vivo stability. The preparation comprises an aqueous solution containing at least one compound selected from D-3-hydroxybutyric acid and water-soluble salts thereof, at least one compound selected from water-soluble bicarbonates, phosphoric acid and water-soluble phosphates, a water-soluble calcium salt, and a water-soluble magnesium salt.

摘要翻译： 用于白内障，青光眼或眼内晶状体移植的眼部手术的冲洗溶液的一次性制剂，其在手术期间和手术后保护眼组织和内皮细胞，并且具有高的体内稳定性。 该制剂包含含有至少一种选自D-3-羟基丁酸及其水溶性盐的化合物的水溶液，至少一种选自水溶性碳酸氢盐，磷酸和水溶性磷酸盐的化合物，水溶性钙 盐和水溶性镁盐。

公开(公告)号：US3935307A

公开(公告)日：1976-01-27

申请号：US474721

申请日：1974-05-30

申请人： Kenji Aimoto ,  Shigeru Hashimoto ,  Toyoaki Yoneda

发明人： Kenji Aimoto ,  Shigeru Hashimoto ,  Toyoaki Yoneda

IPC分类号： A61K8/00 ,  A61K8/73 ,  A61K8/99 ,  A61Q11/00 ,  A61K7/16

CPC分类号： A61Q11/00 ,  A61K8/73

摘要： A liquid or pasty dentifrice comprising, uniformly incorporated therein, a polysaccharide as a thickening and suspending agent, said polysaccharide having a number average molecular weight (Mn) of not less than 100,000 and the molecule of said polysaccharide containing D-glucose, D-mannose, D-galactose and succinic acid in the approximate molar ratio of 1 : 0.03 : 0.1 : 0.2. The polysaccharide is obtained by cultivating Alcaligenes faecalis var. myxogenes in a culture medium containing at least one member selected from the group consisting of lactic acid, pyruvic acid, succinic acid, fumaric acid, malic acid and esters thereof and saccharide.

摘要翻译： 一种液体或糊状洁齿剂，其均匀地掺入多糖作为增稠悬浮​​剂，所述多糖的数均分子量（Mn）不小于100,000，所述多糖含有D-葡萄糖，D-甘露糖的分子 ，D-半乳糖和琥珀酸，其摩尔比为约1:0.03:0.1:0.2。 多糖通过培养粪肠杆菌属产品获得。 含有选自乳酸，丙酮酸，琥珀酸，富马酸，苹果酸及其酯中的至少一种的培养基中的粘液原体和糖。