公开(公告)号：US20070178574A1

公开(公告)日：2007-08-02

申请号：US11467135

申请日：2006-08-24

Applicant: Lydia Mosyak ,  Thomas Rush ,  Xiaotian Zhong ,  Thomas McDonagh ,  Katy Georgiadis ,  Phaik-Eng Sum ,  Edward LaVallie ,  Lisa Collins-Racie ,  Christopher Corcoran ,  Ravindra Kumar ,  Tracy Hebert ,  Stephane Olland ,  Stewart Mackie

Inventor： Lydia Mosyak ,  Thomas Rush ,  Xiaotian Zhong ,  Thomas McDonagh ,  Katy Georgiadis ,  Phaik-Eng Sum ,  Edward LaVallie ,  Lisa Collins-Racie ,  Christopher Corcoran ,  Ravindra Kumar ,  Tracy Hebert ,  Stephane Olland ,  Stewart Mackie

IPC: C12N9/64 ,  G06F19/00

CPC classification number: C12N9/6421 ,  C07K2299/00 ,  C07K2319/00

Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.

公开(公告)号：US07615363B2

公开(公告)日：2009-11-10

申请号：US11467135

申请日：2006-08-24

Applicant: Lidia Mosyak ,  Thomas Saltmarsh Rush, III ,  Xiaotian Zhong ,  Thomas E. McDonagh ,  Katy E. Georgiadis ,  Phaik-Eng Sum ,  Edward R. LaVallie ,  Lisa A. Collins-Racie ,  Christopher John Corcoran ,  Ravindra Kumar ,  Tracy Hebert ,  Stephane Hubert Olland ,  Stewart Andrews Mackie

Inventor： Lidia Mosyak ,  Thomas Saltmarsh Rush, III ,  Xiaotian Zhong ,  Thomas E. McDonagh ,  Katy E. Georgiadis ,  Phaik-Eng Sum ,  Edward R. LaVallie ,  Lisa A. Collins-Racie ,  Christopher John Corcoran ,  Ravindra Kumar ,  Tracy Hebert ,  Stephane Hubert Olland ,  Stewart Andrews Mackie

IPC: C12N9/00 ,  G01N31/00

CPC classification number: C12N9/6421 ,  C07K2299/00 ,  C07K2319/00

Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.

Abstract translation: 本发明涉及聚集蛋白聚糖酶多肽和聚集蛋白聚糖蛋白聚糖酶多肽/配体复合物，聚集蛋白聚糖蛋白聚糖酶和聚集蛋白聚糖酶多肽/配体复合物的晶体，以及相关的方法和软件系统。