公开(公告)号：US20060217402A1

公开(公告)日：2006-09-28

申请号：US11324647

申请日：2006-01-03

申请人： Jill Benner ,  Bettina Gertrud Boehlendorf ,  Martin Kipps ,  Nicolas Eugene Lambert ,  Riet Luck ,  Louis-Pierre Molleyres ,  Snezana Neff ,  Traugott Schuez ,  Paul Stanley

发明人： Jill Benner ,  Bettina Gertrud Boehlendorf ,  Martin Kipps ,  Nicolas Eugene Lambert ,  Riet Luck ,  Louis-Pierre Molleyres ,  Snezana Neff ,  Traugott Schuez ,  Paul Stanley

IPC分类号： A61K31/513 ,  C07D493/02 ,  C12N1/21 ,  C12P17/00 ,  A01N43/54

CPC分类号： C07D493/04

摘要： This invention concerns new biocidal compounds of formula (I) wherein R is H or CH3. Of particular interest are two isomers that are named malayamycin A and desmethylmalayamycin A. These isomers, which may be prepared by growing under controlled conditions a previously unknown strain of micro-organism from the species Streptomyces malaysiensis, are characterised by nmr and mass spectroscopic data. They have biocidal activity, including anti-fungal, anti-viral and anti-cancer activity, and are of special interest for use in agriculture, horticulture, animal and human health.

摘要翻译： 本发明涉及式（I）的新的杀生物化合物，其中R是H或CH 3。 特别令人感兴趣的是称为马来霉素A和去甲基马来霉素A的两种异构体。这些异构体可以通过在受控条件下生长，从马来西亚马链霉菌种的以前未知的微生物菌株生长，其特征在于nmr和质谱数据。 它们具有杀菌活性，包括抗真菌，抗病毒和抗癌活性，对于农业，园艺，动物和人类健康尤为重要。

公开(公告)号：US20050096229A1

公开(公告)日：2005-05-05

申请号：US10501816

申请日：2003-01-10

申请人： Jill Benner ,  Bettina Boehlendorf ,  Martin Kipps ,  Nicolas Lambert ,  Riet Luck ,  Louis-Pierre Molleyres ,  Snezana Neff ,  Traugott Schuez ,  Paul Stanley

发明人： Jill Benner ,  Bettina Boehlendorf ,  Martin Kipps ,  Nicolas Lambert ,  Riet Luck ,  Louis-Pierre Molleyres ,  Snezana Neff ,  Traugott Schuez ,  Paul Stanley

IPC分类号： C12P17/16 ,  A01N47/36 ,  A61K31/513 ,  A61P31/10 ,  A61P31/12 ,  A61P31/18 ,  A61P35/00 ,  C07D20060101 ,  C07D493/04 ,  C12N1/20 ,  C12N1/21 ,  C12R1/465 ,  A01N43/54 ,  C07D493/02

CPC分类号： C07D493/04

摘要： This invention concerns new biocidal compounds of formula (I) wherein R is H or CH3. Of particular interest are two isomers that are named malayamycin A and desmethylmalayamycin A. These isomers, which may be prepared by growing under controlled conditions a previously unknown strain of micro-organism from the species Streptomyces malaysiensis, are characterised by nmr and mass spectroscopic data. They have biocidal activity, including anti-fungal, anti-viral and anti-cancer activity, and are of special interest for use in agriculture, horticulture, animal and human health.

摘要翻译： 本发明涉及式（I）的新的杀生物化合物，其中R是H或CH 3。 特别令人感兴趣的是称为马来霉素A和去甲基马来霉素A的两种异构体。这些异构体可以通过在受控条件下生长，从马来西亚马链霉菌种的以前未知的微生物菌株生长，其特征在于nmr和质谱数据。 它们具有杀菌活性，包括抗真菌，抗病毒和抗癌活性，对于农业，园艺，动物和人类健康尤为重要。