公开(公告)号：US5296221A

公开(公告)日：1994-03-22

申请号：US51274

申请日：1993-04-23

申请人： Tomotari Mitsuoka ,  Kazumasa Suzuki ,  Mitsugu Hayashi ,  Umeyuki Doi ,  Tsuneo Hadeishi

发明人： Tomotari Mitsuoka ,  Kazumasa Suzuki ,  Mitsugu Hayashi ,  Umeyuki Doi ,  Tsuneo Hadeishi

IPC分类号： C12P7/56 ,  A61K37/00 ,  C12N1/00 ,  C12N1/20

CPC分类号： C12R1/23 ,  C12P7/56 ,  Y10S435/853

摘要： The present invention comprises a novel strain of Lactobacillus johnsonni FERM BP-2680, a lactic acid bacteria preparation using the Lactobacillus johnsonni FERM BP-2680, and a process of manufacturing the lactic acid bacteria preparation. The process includes the steps of inoculating the Lactobacillus johnsonni FERM BP-2680 into a medium containing fermentable sugar as a major carbon source, cultivating and proliferating under cultivation conditions adapted to anaerobes or facultative anaerobes, and further isolating the Lactobacillus johnsonni from the medium and drying the isolated Lactobacillus johnsonni with a protective agent to produce the lactic acid bacteria preparation. Optionally a bulking agent may be added to control cell concentration of the preparation. The preparation containing Lactobacillus johnsonni FERM BP-2680 is used to suppress harmful bacteria in the digestive tract of mammals.

摘要翻译： 本发明包括新型的约氏乳杆菌FERM BP-2680菌株，使用约氏乳杆菌FERM BP-2680的乳酸菌制剂和制备乳酸菌制剂的方法。 该方法包括以下步骤：将约翰逊乳杆菌FERM BP-2680接种到含有可发酵糖作为主要碳源的培养基中，在适合于厌氧菌或兼性厌氧菌的培养条件下培养和增殖，并进一步从培养基中分离出约氏乳杆菌 分离的约氏乳杆菌用保护剂制备乳酸菌制剂。 任选地，可以加入填充剂以控制制剂的细胞浓度。 含有Lactobacillus johnsonni FERM BP-2680的制剂用于抑制哺乳动物消化道中的有害细菌。