公开(公告)号：US20180036355A1

公开(公告)日：2018-02-08

申请号：US15624083

申请日：2017-06-15

申请人： DUPONT NUTRITION BIOSCIENCES APS

发明人： PIERRE DESREUMAUX ,  Didier Carcano

IPC分类号： A61K35/747 ,  G01N33/74 ,  A23K10/18 ,  G01N33/50 ,  A23L33/135 ,  C12R1/23 ,  C12Q1/68

CPC分类号： A61K35/747 ,  A23C9/1234 ,  A23C9/152 ,  A23K10/18 ,  A23L2/52 ,  A23L33/135 ,  A23V2002/00 ,  A23Y2220/03 ,  A61K35/744 ,  A61K35/745 ,  A61K2035/115 ,  C12Q1/6876 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12R1/23 ,  G01N33/5023 ,  G01N33/74 ,  G01N33/948 ,  G01N33/9486 ,  G01N2333/726 ,  A61K2300/00

摘要： The invention proposes the use of at least one strain of Lactobacillus acidophilus to prepare a support administered to humans or animals with an analgesic purpose in the gastrointestinal system.

公开(公告)号：US20180028581A1

公开(公告)日：2018-02-01

申请号：US15457205

申请日：2017-03-13

申请人： DUPONT NUTRITION BIOSCIENCES APS

发明人： VERONIQUE DENNIN ,  GREGORY John LEYER ,  ANNICK MERCENIER ,  SOPHIE NUTTEN ,  BRUNO POT

IPC分类号： A61K35/745 ,  C12R1/23 ,  C12R1/225 ,  C12R1/01 ,  C12N1/20 ,  A61K35/747 ,  C12R1/25

CPC分类号： A61K35/745 ,  A61K35/747 ,  C12N1/20 ,  C12R1/01 ,  C12R1/225 ,  C12R1/23 ,  C12R1/25

摘要： The subject of the present invention is a bacterial composition having immunomodulation properties comprising at least one strain selected from the group consisting of Lactobacillus acidophilus PTA-4797, Lactobacillus plantarum PTA-4799, Lactobacillus salivarius PTA-4800, Lactobacillus paracasei PTA-4798, Bifidobacterium bifidum PTA-4801 and Bifidobacterium lactis PTA-4802. An other subject of the invention is an immunomodulation method comprising the step of using the at least one strain selected from the preceding group.

公开(公告)号：US20170348364A1

公开(公告)日：2017-12-07

申请号：US15686971

申请日：2017-08-25

申请人： MICROBIOS, INC.

发明人： Matthew Ryan GARNER ,  Joseph F. Flint

IPC分类号： A61K35/747 ,  C12N1/20 ,  C12N1/04 ,  A23K50/20 ,  A23K50/10 ,  A23K50/80 ,  A23K50/75 ,  A23K50/30 ,  C12R1/23 ,  A23K10/18

CPC分类号： A61K35/747 ,  A23K10/18 ,  A23K50/10 ,  A23K50/20 ,  A23K50/30 ,  A23K50/75 ,  A23K50/80 ,  A23Y2220/79 ,  C12N1/04 ,  C12N1/20 ,  C12R1/23

摘要： Processes to produce microorganisms that can be incorporated into a microbial-based product that results in high viable cell yields and shelf-stable products are disclosed. These microbial-based products are useful for inhibiting pathogenic growth and as a food additive. A preferred microorganism is a lactic acid producing bacteria. In one embodiment, the process comprises inoculating a lactobacillus fermentation medium with lactic acid producing bacterial cells, harvesting the lactic acid producing bacterial cells at least partially during the log phases, concentrating the lactic acid producing bacterial cells, and preserving the lactic acid producing bacterial cells at a concentration of at least 5×109 cfu/ml.

公开(公告)号：US20170224747A1

公开(公告)日：2017-08-10

申请号：US15269257

申请日：2016-09-19

申请人： BASF SE

发明人： Andreas Reindl ,  Rolf Knöll ,  Christine Lang ,  Markus Veen ,  Eckhard Budde ,  Mewes Boettner

IPC分类号： A61K35/747 ,  A61Q15/00 ,  C12N1/20 ,  A61K8/99

CPC分类号： A61K35/747 ,  A61K8/99 ,  A61K35/74 ,  A61K2800/10 ,  A61Q15/00 ,  C12N1/20 ,  C12R1/15 ,  C12R1/225 ,  C12R1/23 ,  C12R1/25

摘要： Described are microorganisms which are able to suppress the production of malodorous compounds by axillary bacteria. Also described are compositions comprising such microorganisms as well as the use of such micoorganisms in cosmetic, prophylactic or therapeutic applications.

公开(公告)号：US09539293B2

公开(公告)日：2017-01-10

申请号：US14232475

申请日：2012-07-13

申请人： Denise Kelly

发明人： Denise Kelly

IPC分类号： A61K35/74 ,  A61K35/747 ,  C12R1/225 ,  C12R1/23 ,  C12R1/25 ,  C12N1/20

CPC分类号： A61K35/747 ,  A23K10/18 ,  A23L33/135 ,  A23V2002/00 ,  C12N1/20 ,  C12R1/225 ,  C12R1/23 ,  C12R1/25 ,  Y02A50/473 ,  Y02A50/481

摘要： Described herein are porcine lactic acid bacterial strain compositions and processes of obtaining porcine lactic acid bacterial strains. Further aspects of the invention relate to food additives, supplements and probiotic compositions comprising said bacterial strains, and therapeutic uses of said bacterial strain compositions.

摘要翻译： 本文描述的是猪乳酸菌株组合物和获得猪乳酸菌菌株的方法。 本发明的其它方面涉及包含所述细菌菌株的食品添加剂，补充剂和益生菌组合物以及所述细菌菌株组合物的治疗用途。

公开(公告)号：US09493737B2

公开(公告)日：2016-11-15

申请号：US14239491

申请日：2012-08-20

申请人： Tania Ivanova Georgieva ,  Anders Clausen ,  Tina Malling Thorsen

发明人： Tania Ivanova Georgieva ,  Anders Clausen ,  Tina Malling Thorsen

IPC分类号： C12N1/00 ,  C12N1/20 ,  C12N1/04 ,  C12R1/01 ,  C12R1/225 ,  C12R1/23 ,  C12R1/46

CPC分类号： C12N1/20 ,  C12N1/04 ,  C12R1/01 ,  C12R1/225 ,  C12R1/23 ,  C12R1/46

摘要： The present invention relates to a process for providing purified bacteria-containing concentrates, comprising at least the steps of adding an aqueous solution to a first bacteria-containing concentrate to provide a bacteria-containing suspension, wherein the volume of the added aqueous solution is in the range of 0.3 liters to 10 liters per liter of said first bacteria-containing concentrate; and concentrating said bacteria-containing suspension to provide a second bacteria-containing concentrate. Further, the present invention relates to the purified concentrates per se.

摘要翻译： 本发明涉及提供纯化的含细菌的浓缩物的方法，该方法至少包括向第一含细菌的浓缩物中加入水溶液以提供含细菌的悬浮液，其中加入的水溶液的体积为 每升所述第一含细菌浓度为0.3升至10升的范围; 并浓缩所述含细菌的悬浮液以提供第二细菌浓缩物。 此外，本发明涉及纯化的浓缩物本身。

公开(公告)号：US20150023936A1

公开(公告)日：2015-01-22

申请号：US14506065

申请日：2014-10-03

申请人： DUPONT NUTRITION BIOSCIENCES APS

发明人： Pierre Desreumaux ,  Didier Carcano

IPC分类号： A61K35/74 ,  A23C9/152 ,  A23L2/52 ,  A23L1/30

CPC分类号： A61K35/747 ,  A23C9/1234 ,  A23C9/152 ,  A23K10/18 ,  A23L2/52 ,  A23L33/135 ,  A23V2002/00 ,  A23Y2220/03 ,  A61K35/744 ,  A61K35/745 ,  A61K2035/115 ,  C12Q1/6876 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12R1/23 ,  G01N33/5023 ,  G01N33/74 ,  G01N33/948 ,  G01N33/9486 ,  G01N2333/726 ,  A61K2300/00

摘要： The invention proposes the use of at least one strain of Lactobacillus acidophilus to prepare a support administered to humans or animals with an analgesic purpose in the gastrointestinal system.

摘要翻译： 本发明提出使用至少一种嗜酸乳杆菌菌株来制备在胃肠系统中以止痛目的施用于人或动物的支持物。

公开(公告)号：US20140004070A1

公开(公告)日：2014-01-02

申请号：US14018852

申请日：2013-09-05

申请人： Andreas Reindl ,  Rolf Knöll ,  Christine Lang ,  Markus Veen ,  Eckhard Budde ,  Mewes Boettner

发明人： Andreas Reindl ,  Rolf Knöll ,  Christine Lang ,  Markus Veen ,  Eckhard Budde ,  Mewes Boettner

IPC分类号： C12N1/20

CPC分类号： A61K35/747 ,  A61K8/99 ,  A61K35/74 ,  A61K2800/10 ,  A61Q15/00 ,  C12N1/20 ,  C12R1/15 ,  C12R1/225 ,  C12R1/23 ,  C12R1/25

摘要： Described are microorganisms which are able to suppress the production of malodorous compounds by axillary bacteria. Also described are compositions comprising such microorganisms as well as the use of such microorganisms in cosmetic, prophylactic or therapeutic applications.

摘要翻译： 描述了能够抑制腋芽细菌产生恶臭化合物的微生物。 还描述了包含这种微生物的组合物以及这些微生物在化妆品，预防或治疗应用中的用途。

公开(公告)号：US08071086B2

公开(公告)日：2011-12-06

申请号：US12778509

申请日：2010-05-12

申请人： Véronique Dennin ,  Gregory John Leyer ,  Annick Mercenier ,  Sophie Nutten ,  Bruno Pot

发明人： Véronique Dennin ,  Gregory John Leyer ,  Annick Mercenier ,  Sophie Nutten ,  Bruno Pot

IPC分类号： C12N1/20 ,  A01N1/20 ,  A61K35/74

CPC分类号： A61K35/745 ,  A61K35/747 ,  C12N1/20 ,  C12R1/01 ,  C12R1/225 ,  C12R1/23 ,  C12R1/25

摘要： The subject of the present invention is a bacterial composition having immunomodulation properties comprising at least one strain selected from the group consisting of Lactobacillus acidophilus PTA-4797, Lactobacillus plantarum PTA-4799, Lactobacillus salivarius PTA-4800, Lactobacillus paracasei PTA-4798, Bifidobacterium bifidum PTA-4801 and Bifidobacterium lactis PTA-4802. An other subject of the invention is an immunomodulation method comprising the step of using the at least one strain selected from the preceding group.

摘要翻译： 本发明的主题是具有免疫调节特性的细菌组合物，其包含选自嗜酸乳杆菌PTA-4797，植物乳杆菌PTA-4799，唾液乳杆菌PTA-4800，副干酪乳杆菌PTA-4798，双歧杆菌双歧杆菌 PTA-4801和乳酸双歧杆菌PTA-4802。 本发明的另一主题是免疫调节方法，其包括使用选自前述组的至少一种菌株的步骤。

公开(公告)号：US20110117068A1

公开(公告)日：2011-05-19

申请号：US12377712

申请日：2007-08-20

申请人： Christine Lang ,  Stefanie Arya ,  Natalia Bolotina ,  Markus Veen ,  Mewes Böttner ,  Eckhard Budde ,  Andreas Künkel ,  Angelika-Maria Pfeiffer

发明人： Christine Lang ,  Stefanie Arya ,  Natalia Bolotina ,  Markus Veen ,  Mewes Böttner ,  Eckhard Budde ,  Andreas Künkel ,  Angelika-Maria Pfeiffer

IPC分类号： A61K35/74 ,  C12N1/20 ,  C12N1/16 ,  A61P1/14 ,  A61K36/062 ,  A61K36/06

CPC分类号： C12R1/225 ,  A23L29/065 ,  A23V2002/00 ,  A23Y2220/00 ,  A61K35/747 ,  A61K36/064 ,  A61K36/07 ,  C12R1/23 ,  C12R1/25 ,  C12R1/645 ,  C12R1/72 ,  A23V2200/3204

摘要： Described are microorganism which are able to reduce the generation of feces odor by decreasing the amount of at least one of the compounds methyl mercaptan, a sulphide compound, cadavarine, putrescine, indole or skatole, and wherein said decrease in the amount of said compounds is independent of the growth of the microorganism. Also described are compositions, comprising such microorganisms, e.g. food, feed or pharmaceutical compositions and the use of such microorganisms for suppressing feces odor or the preparation of foodstuff or feedstuff, as well as corresponding methods for the production of food or feed composition and additives for food, feed or drinks.

摘要翻译： 描述了能够通过减少化合物中的至少一种化合物甲硫醇，硫化物化合物，卡那霉素，腐胺，吲哚或粪便来减少粪便气味的产生的微生物，并且其中所述化合物的量的减少是 独立于微生物的生长。 还描述了包含这样的微生物的组合物，例如。 食品，饲料或药物组合物以及这些微生物用于抑制粪便气味或食品或饲料的制备，以及用于生产食品，饲料组合物和用于食品，饲料或饮料的添加剂的相应方法。