Pharmaceutical hydrophilic spray containing nitroglycerin for treating
angina
    2.
    发明授权
    Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina 失效
    含硝酸甘油的药物亲水性喷雾用于治疗心绞痛

    公开(公告)号:US5370862A

    公开(公告)日:1994-12-06

    申请号:US989987

    申请日:1992-12-11

    IPC分类号: A61K9/00 A61K9/12 A61K31/21

    CPC分类号: A61K9/006 A61K31/21

    摘要: A pharmaceutical aerosol spray for treating an angina attack including a container having a liquid composition therein comprising 0.1 to 2 weight percent of nitroglycerin, 2 to 60 weight percent of ethanol, 2 to 60 weight percent of propylene glycol, 10 to 50 weight percent of dichlorodifluoromethane and 30 to 70 weight percent of dichlorotetrafluoroethane, the container having a valve assembly sealed to the container around an opening in the container by a sealant material which has a nitroglycerin absorption value less than 10 mg/1 g of sealant material.

    摘要翻译: 一种用于治疗心绞痛发作的药物喷雾剂,包括其中含有液体组合物的容器,其中含有0.1至2重量%的硝酸甘油,2至60重量%的乙醇,2至60重量%的丙二醇,10至50重量%的二氯二氟甲烷 和30至70重量%的二氯四氟乙烷,所述容器具有阀组件,其通过密封剂材料密封到容器周围的容器上,所述密封剂材料具有小于10mg / 1g密封材料的硝酸甘油吸收值。

    Thermoelectric sensor
    3.
    发明授权
    Thermoelectric sensor 失效
    热电传感器

    公开(公告)号:US6040579A

    公开(公告)日:2000-03-21

    申请号:US030025

    申请日:1998-02-25

    IPC分类号: G01K7/02 G01J5/12 H01L35/32

    CPC分类号: G01J5/12

    摘要: Thermoelectric sensor (12) formed by a membrane (14) including a plurality of thermoelectric elements (20) formed of a plurality of thermoelectric couples and forming a plurality of elementary cells. Each elementary cell is thermally insulated from adjacent elementary cells by metal wires (22, 23), preferably gold wires, arranged on the front face (25) of the membrane (14), more particularly, on an upper passivation layer (30). The metal wires (22 and 23) are thermally connected to a substrate (16) supporting said membrane. The two wires separating two adjacent thermoelectric elements (20) are separated from each other by an intermediate low thermal conduction region (28).

    摘要翻译: 由包括由多个热电偶形成的多个热电元件(20)形成多个元件单元的膜(14)形成的热电传感器(12)。 更具体地说,在上钝化层(30)上,金属线(22,23),最好是金线布置在隔膜(14)的前表面(25)上,每个元件与相邻元件电池绝热。 金属线(22和23)热连接到支撑所述膜的基底(16)。 分离两个相邻的热电元件(20)的两条线通过中间的低热传导区域(28)彼此分开。

    Transdermal medication system for isosorbide dinitrate
    5.
    发明授权
    Transdermal medication system for isosorbide dinitrate 失效
    硝酸异山梨酯的透皮用药体系

    公开(公告)号:US4293565A

    公开(公告)日:1981-10-06

    申请号:US82490

    申请日:1979-10-09

    CPC分类号: A61K31/34 A61K9/7023

    摘要: A pharmaceutical preparation comprising:(a) isosorbide dinitrate as active ingredient(b) a solvent for isosorbide dinitrate(c) an ointment consistency agent(d) an emulsifying agent(e) water, and(f) possibly customary preservatives, antioxidants, buffers and/or odorants;where the weight ratio of water: consistency agent including emulsifying agent: solvent is 30 to 80: 3 to 35: 3 to 35, the amount of emulsifying agent is from 0% to 15% by weight and the amount of isosorbide dinitrate is from 2% to 20% by weight. The preparation has an ointment-like consistency and is administered topically to the skin, where it has a high adsorption rate and a long duration of response.

    摘要翻译: 一种药物制剂,其包含:(a)硝酸异山梨酯作为活性成分(b)硝酸异山梨酯的溶剂(c)软膏稠度剂(d)乳化剂(e)水,和(f)可能的常规防腐剂,抗氧化剂,缓冲剂 和/或气味剂; 其中水:稠度剂(包括乳化剂:溶剂)的重量比为30〜80:3〜35:3〜35,乳化剂的含量为0〜15重量%,硝酸异山梨酯的含量为2 %至20重量%。 该制剂具有软膏状稠度,并且局部施用于皮肤,其具有高的吸附速率和较长的反应持续时间。

    Nitroglycerin-containing hydrophilic aqueous pumpable spray composition
    7.
    发明授权
    Nitroglycerin-containing hydrophilic aqueous pumpable spray composition 失效
    含硝酸甘油的亲水性可泵送喷雾组合物

    公开(公告)号:US5744124A

    公开(公告)日:1998-04-28

    申请号:US890314

    申请日:1992-05-26

    CPC分类号: A61K9/006 A61K31/21

    摘要: A hydrophilic aqueous pump spray composition for treating angina pectoris comprising 0.15 to 0.50 weight/% of nitroglycerin, 24.50 to 24.85 weight/% of ethanol, 32.00 weight/% of 1,2-propyleneglycol and 43.00 weight/% of purified water and having a pH of 3 to 6; a method of producing the composition; and, a product comprising a container having the composition as a solution therein and provided with a dosage dispensing pump.

    摘要翻译: 一种用于治疗心绞痛的亲水性含水泵喷雾组合物,其包含0.15至0.50重量%的硝酸甘油,24.50至24.85重量/%的乙醇,32.00重量%的1,2-丙二醇和43.00重量%的纯化水, pH为3〜6; 一种制备该组合物的方法; 以及包含具有组合物作为溶液的容器并具有剂量分配泵的产品。