摘要:
Delayed release pharmaceutical preparations include a solvent free, solidified melt granulate of a pharmaceutical ingredient in admixture with a meltable auxiliary substance which is soluble in the pharmaceutical ingredient at elevated temperatures.
摘要:
A pharmaceutical aerosol spray for treating an angina attack including a container having a liquid composition therein comprising 0.1 to 2 weight percent of nitroglycerin, 2 to 60 weight percent of ethanol, 2 to 60 weight percent of propylene glycol, 10 to 50 weight percent of dichlorodifluoromethane and 30 to 70 weight percent of dichlorotetrafluoroethane, the container having a valve assembly sealed to the container around an opening in the container by a sealant material which has a nitroglycerin absorption value less than 10 mg/1 g of sealant material.
摘要:
Thermoelectric sensor (12) formed by a membrane (14) including a plurality of thermoelectric elements (20) formed of a plurality of thermoelectric couples and forming a plurality of elementary cells. Each elementary cell is thermally insulated from adjacent elementary cells by metal wires (22, 23), preferably gold wires, arranged on the front face (25) of the membrane (14), more particularly, on an upper passivation layer (30). The metal wires (22 and 23) are thermally connected to a substrate (16) supporting said membrane. The two wires separating two adjacent thermoelectric elements (20) are separated from each other by an intermediate low thermal conduction region (28).
摘要:
A method of preparing pharmaceutical preparations for oral administration, free of organic solvents. The method employs solidified melt granulates of an active ingredient in admixture with a meltable auxiliary substance which is soluble in the active ingredient at elevated temperatures.
摘要:
A pharmaceutical preparation comprising:(a) isosorbide dinitrate as active ingredient(b) a solvent for isosorbide dinitrate(c) an ointment consistency agent(d) an emulsifying agent(e) water, and(f) possibly customary preservatives, antioxidants, buffers and/or odorants;where the weight ratio of water: consistency agent including emulsifying agent: solvent is 30 to 80: 3 to 35: 3 to 35, the amount of emulsifying agent is from 0% to 15% by weight and the amount of isosorbide dinitrate is from 2% to 20% by weight. The preparation has an ointment-like consistency and is administered topically to the skin, where it has a high adsorption rate and a long duration of response.
摘要:
Supersaturated aqueous to organic solvent solution of isosorbide dinitrate, process of preparation at elevated temperatures, and use of the supersaturated solutions for the production of infusion solutions.
摘要:
A hydrophilic aqueous pump spray composition for treating angina pectoris comprising 0.15 to 0.50 weight/% of nitroglycerin, 24.50 to 24.85 weight/% of ethanol, 32.00 weight/% of 1,2-propyleneglycol and 43.00 weight/% of purified water and having a pH of 3 to 6; a method of producing the composition; and, a product comprising a container having the composition as a solution therein and provided with a dosage dispensing pump.
摘要:
Preparation that can be dissolved in water to form an approximately isotonic nitroglycerine solution having a concentration of approximately 1 mg of nitroglycerine/ml of solution.