-
1.发明授权
公开(公告)号：US5744124A
公开(公告)日：1998-04-28
申请号：US890314
申请日：1992-05-26
IPC分类号： A61K9/12 , A61K9/00 , A61K9/72 , A61K31/21 , A61K47/10 , A61P9/06 , A61P9/08 , A61P9/10 , A61K31/04
摘要： A hydrophilic aqueous pump spray composition for treating angina pectoris comprising 0.15 to 0.50 weight/% of nitroglycerin, 24.50 to 24.85 weight/% of ethanol, 32.00 weight/% of 1,2-propyleneglycol and 43.00 weight/% of purified water and having a pH of 3 to 6; a method of producing the composition; and, a product comprising a container having the composition as a solution therein and provided with a dosage dispensing pump.
摘要翻译： 一种用于治疗心绞痛的亲水性含水泵喷雾组合物，其包含0.15至0.50重量％的硝酸甘油，24.50至24.85重量/％的乙醇，32.00重量％的1,2-丙二醇和43.00重量％的纯化水， pH为3〜6; 一种制备该组合物的方法; 以及包含具有组合物作为溶液的容器并具有剂量分配泵的产品。
-
2.发明授权Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina 失效含硝酸甘油的药物亲水性喷雾用于治疗心绞痛
公开(公告)号：US5370862A
公开(公告)日：1994-12-06
申请号：US989987
申请日：1992-12-11
摘要： A pharmaceutical aerosol spray for treating an angina attack including a container having a liquid composition therein comprising 0.1 to 2 weight percent of nitroglycerin, 2 to 60 weight percent of ethanol, 2 to 60 weight percent of propylene glycol, 10 to 50 weight percent of dichlorodifluoromethane and 30 to 70 weight percent of dichlorotetrafluoroethane, the container having a valve assembly sealed to the container around an opening in the container by a sealant material which has a nitroglycerin absorption value less than 10 mg/1 g of sealant material.
摘要翻译： 一种用于治疗心绞痛发作的药物喷雾剂，包括其中含有液体组合物的容器，其中含有0.1至2重量％的硝酸甘油，2至60重量％的乙醇，2至60重量％的丙二醇，10至50重量％的二氯二氟甲烷 和30至70重量％的二氯四氟乙烷，所述容器具有阀组件，其通过密封剂材料密封到容器周围的容器上，所述密封剂材料具有小于10mg / 1g密封材料的硝酸甘油吸收值。
-
公开(公告)号：US5773032A
公开(公告)日：1998-06-30
申请号：US661017
申请日：1996-06-10
IPC分类号： A61K38/02 , A61K9/10 , A61K9/107 , A61K9/50 , A61K38/04 , A61K38/08 , A61K38/09 , A61K38/10 , A61K38/25 , A61K38/31 , A61P5/06 , A61P13/02 , A61P15/00 , A61P35/00 , C07K2/00 , C07K7/08 , C07K7/23 , C07K14/60 , C07K14/655
CPC分类号： A61K38/105 , A61K38/09
摘要： Poorly soluble salts of LHRH analogues, for example cetrorelix embonate, display an intrinsic sustained release effect in the grain size 5 .mu.m to 200 .mu.m.
摘要翻译： LHRH类似物的不溶性盐，例如碳巧酸氯替卡酯，在5μm至200μm的晶粒尺寸中显示出本征的缓释作用。
-
4.发明授权
公开(公告)号：US5472710A
公开(公告)日：1995-12-05
申请号：US235188
申请日：1994-04-29
CPC分类号： A61K9/5084 , A61K9/5078
摘要： Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture. Pharmaceutical preparation to be administered orally with controlled release of active substance, containing a nucleus which itself consists at least of one pharmacologically active substance, or a nucleus of physiologically safe material which is enveloped by an active substance layer, containing at least one pharmacologically active substance, if needed, a first membrane, then an acid layer consisting at least of a physiologically safe acid and then a compound membrane consisting of a pH sensitive polymer and an insoluble polymer, as well as methods for its manufacture. The pharmaceutical preparation is applicable to all claimed types of medicine and to the therapy of illnesses.
摘要翻译： 用活性物质控制释放的口服药物制剂及其制造方法。 含有活性物质的控制释放的药物制剂，其含有至少一种药理学活性物质的细胞核或由活性物质层包围的至少一种药理活性物质的生理安全材料的核， 如果需要，第一膜，然后是至少由生理安全的酸组成的酸层，然后由pH敏感聚合物和不溶性聚合物组成的复合膜，以及其制造方法。 药物制剂适用于所有要求类型的药物和治疗疾病。
-
5.发明授权Glass container internally coated with a silicone and having an in situ freeze-dried solid product therein, and process of making the same 失效内部涂有硅树脂并在其中具有原位冻干固体产品的玻璃容器及其制备方法
公开(公告)号：US5335769A
公开(公告)日：1994-08-09
申请号：US972076
申请日：1992-11-05
CPC分类号： A61J1/06 , B65D23/02 , Y10T428/1321 , Y10T428/31612
摘要： A freeze-drying process which reduces loss of the freeze-dried product comprising adding a liquid solution comprising a solid product dissolved in a solvent to a glass container having its inside surface coated with a silicone material; subjecting the container with the liquid solution therein to acceptable operable freeze-drying conditions to remove the solvent and leave the solid product in the container in the form of a dense compact coherent solid; and sealing the container to maintain the solid product stable over a useful storage shelf life.An article of manufacture comprising a sealed glass container having its inside surface coated with a silicone material and containing an in situ freeze-dried dense compact coherent solid product.
摘要翻译： 一种降低冷冻干燥产品损失的冷冻干燥方法，包括将溶解在溶剂中的固体产物的液体溶液添加到其内表面涂有硅酮材料的玻璃容器中; 将容器中的液体溶液经受可接受的可操作的冷冻干燥条件以除去溶剂，并将固体产物留在容器中，形式为致密紧密的粘结固体; 并密封容器以保持固体产品在有用的储存保质期内稳定。 一种制品，其包括密封的玻璃容器，其内表面涂覆有硅氧烷材料并且包含原位冷冻干燥的致密紧密相干固体产品。
-
-
-
-
搜索结果
5 条记录 (耗时 0.013 秒)
