公开(公告)号：US08597610B2

公开(公告)日：2013-12-03

申请号：US12663179

申请日：2008-06-09

Applicant: Martin Järvekülg ,  Valter Reedo ,  Uno Mäeorg ,  Ilmar Kink ,  Ants Löhmus

Inventor： Martin Järvekülg ,  Valter Reedo ,  Uno Mäeorg ,  Ilmar Kink ,  Ants Löhmus

IPC: B32B1/08 ,  B29C37/00

CPC classification number: C01B13/32 ,  B82Y30/00 ,  C01G23/053 ,  C01G25/02 ,  C01G27/02 ,  C01P2004/03 ,  C01P2004/12 ,  C01P2004/13 ,  C01P2004/136 ,  Y10T428/13

Abstract: In the current invention a method for the preparation of an oxide material was described that involves bringing the sol onto the substrate, the gelation of the solution and thermal treatment of the gel. Alkoxides are used as precursor materials for the sol preparation and substrate free structures are employed for the manufacturing of the oxide material. A gel film with thickness ranging from 5 nm to 1 μm is created onto the sol layer. The gelled film is separated into pieces by self organizing and the gelled part is disconnected from the substrate. Substrate free tubular structures with diameters ranging from 0.01-100 μm are formed of the gel film which are then heated at temperature range of 200-1600 C during a period of 5 minutes to 10 hours. The manufactured oxide materials are employed as catalysts, gas sensors, stationary phases of chromatographic columns, composite materials, thermal isolation materials and micro- or nano electronic mechanical systems (MEMS or NEMS) components.

Abstract translation: 在本发明中，描述了一种制备氧化物材料的方法，其包括将溶胶引入到基底上，溶液的凝胶化和凝胶的热处理。 使用Alkoxides作为溶胶制备的前体材料，并且使用无底物结构来制造氧化物材料。 在溶胶层上形成厚度为5nm〜1μm的凝胶膜。 凝胶膜通过自组织分离成片，并将胶凝部分与基材断开。 直径范围为0.01〜100μm的基体自由管状结构由凝胶膜形成，然后将其在200-1600℃的温度范围内加热5分钟至10小时。 所制造的氧化物材料用作催化剂，气体传感器，色谱柱的固定相，复合材料，热隔离材料和微纳米电子机械系统（MEMS或NEMS）组件。

公开(公告)号：US20140186623A1

公开(公告)日：2014-07-03

申请号：US13981276

申请日：2011-12-31

Applicant: Marko Part ,  Tanel Tätte ,  Uno Mäeorg ,  Valter Kiisk ,  Gunnar Nurk ,  Aleksei Vorobjov ,  Kelli Hanschmidt

Inventor： Marko Part ,  Tanel Tätte ,  Uno Mäeorg ,  Valter Kiisk ,  Gunnar Nurk ,  Aleksei Vorobjov ,  Kelli Hanschmidt

IPC: C04B35/624

CPC classification number: C04B35/624 ,  B82Y30/00 ,  C04B35/62231 ,  C04B35/6225 ,  C04B35/6264 ,  C04B35/6269 ,  C04B2235/3217 ,  C04B2235/3224 ,  C04B2235/3225 ,  C04B2235/3229 ,  C04B2235/3239 ,  C04B2235/3244 ,  C04B2235/441 ,  C04B2235/5284 ,  C04B2235/6021 ,  C04B2235/606 ,  C04B2235/762 ,  C04B2235/765 ,  C04B2235/96 ,  D01D5/24 ,  D01F9/10 ,  Y10T428/2975

Abstract: The present invention prescribes a new sol-gel method of preparing and formation of the metal oxide microtubes. According to the method firstly is prepared the precursor sol from metal oxides or mixtures of metal oxides and alkoxides, thereafter from the precursor sol are extruded the fibres, which are gelatinised afterwards until the inner sol which is less viscous of fibres is converted to thinner wall until alcohol from the precursor is left trough walls. The metal oxide microtubes are applicable as to conduct liquids or gasses, as ionic conductors, as catalyst carriers and as light emitters.

Abstract translation: 本发明规定了制备和形成金属氧化物微管的新的溶胶 - 凝胶法。 根据该方法首先从金属氧化物或金属氧化物和醇盐的混合物制备前体溶胶，然后从前体溶胶挤出纤维，然后将其糊化，直到纤维粘度较低的内部溶胶转化为更薄的壁 直到来自前体的酒精离开槽壁。 金属氧化物微管可应用于作为离子导体，作为催化剂载体和发光体进行液体或气体。

公开(公告)号：US20100274031A1

公开(公告)日：2010-10-28

申请号：US12768014

申请日：2010-04-27

Applicant: Olga Tsubrik ,  Andrus Tasa ,  Ain Uustare ,  Ago Rinken ,  Uno Mäeorg ,  Kristiina Ylihonko ,  Maria Holmbäck ,  Jukka Raunio

Inventor： Olga Tsubrik ,  Andrus Tasa ,  Ain Uustare ,  Ago Rinken ,  Uno Mäeorg ,  Kristiina Ylihonko ,  Maria Holmbäck ,  Jukka Raunio

IPC: C07D309/10

CPC classification number: C07D309/10

Abstract: Methods for producing amrubicin and structural analogs thereof. The present invention encompasses synthetic pathways for the production of amrubicin (Formula I) and structural analogs thereof. The synthetic pathways of the present invention preferably employ as a starting material an anthracycline compound having the generic Formula II: Compounds of Formula II may have any combination of the following identities for the indicated moieties: R1, R2, R3, R4, and R8 may be H, OH, or alkoxy; R5 may be H, alkyl, or alkoxycarbonyl; R6 may be H or alkyl; R7 may be OH or alkyl. In certain embodiments, ε-rhodomycinone or daunomycinone may be used as starting materials according to Formula II. The present invention employs a compound of Formula II as part of a semi-synthetic method that combines traditional chemical synthetic steps with biosynthetic steps to produce amrubicin, derivatives thereof, and structural analogs thereof. The methods of the present invention preferably include a glycosylation reaction whereby an algycon of amrubicin or structural analog thereof is glycosylated to produce the final product.

Abstract translation: 生产氨柔比星的方法及其结构类似物。 本发明包括用于生产氨柔比星（式I）及其结构类似物的合成途径。 本发明的合成途径优选使用具有通式II的蒽环类化合物作为起始物质：式II化合物可以具有以下特征的任意组合：R1，R2，R3，R4和R8可以 为H，OH或烷氧基; R5可以是H，烷基或烷氧基羰基; R6可以是H或烷基; R 7可以是OH或烷基。 在某些实施方案中，可以使用霉素霉素酮或道诺霉素酮作为根据式II的原料。 本发明使用式II化合物作为将传统化学合成步骤与生物合成步骤结合以产生氨柔比星，其衍生物及其结构类似物的半合成方法的一部分。 本发明的方法优选包括糖基化反应，由此将氨柔比星或其结构类似物的脂肪糖糖基化以产生最终产物。

公开(公告)号：US20100183829A1

公开(公告)日：2010-07-22

申请号：US12663179

申请日：2008-06-09

Applicant: Martin Järvekülg ,  Valter Reedo ,  Uno Mäeorg ,  Ilmar Kink ,  Ants Löhmus

Inventor： Martin Järvekülg ,  Valter Reedo ,  Uno Mäeorg ,  Ilmar Kink ,  Ants Löhmus

IPC: B32B1/08 ,  B29C37/00

CPC classification number: C01B13/32 ,  B82Y30/00 ,  C01G23/053 ,  C01G25/02 ,  C01G27/02 ,  C01P2004/03 ,  C01P2004/12 ,  C01P2004/13 ,  C01P2004/136 ,  Y10T428/13

Abstract: In the current invention a method for the preparation of an oxide material was described that involves bringing the sol onto the substrate, the gelation of the solution and thermal treatment of the gel. Alkoxides are used as precursor materials for the sol preparation and substrate free structures are employed for the manufacturing of the oxide material. A gel film with thickness ranging from 5 nm to 1 μm is created onto the sol layer. The gelled film is separated into pieces by self organizing and the gelled part is disconnected from the substrate. Substrate free tubular structures with diameters ranging from 0.01-100 μm are formed of the gel film which are then heated at temperature range of 200-1600 C during a period of 5 minutes to 10 hours. The manufactured oxide materials are employed as catalysts, gas sensors, stationary phases of chromatographic columns, composite materials, thermal isolation materials and micro- or nano electronic mechanical systems (MEMS or NEMS) components.

Abstract translation: 在本发明中，描述了一种制备氧化物材料的方法，其包括将溶胶引入到基底上，溶液的凝胶化和凝胶的热处理。 使用Alkoxides作为溶胶制备的前体材料，并且使用无底物结构来制造氧化物材料。 在溶胶层上形成厚度为5nm至1μm的凝胶膜。 凝胶膜通过自组织分离成片，并将胶凝部分与基材断开。 直径范围为0.01-100μm的基体自由管状结构由凝胶膜形成，然后将其在200-1600℃的温度范围内加热5分钟至10小时。 所制造的氧化物材料用作催化剂，气体传感器，色谱柱的固定相，复合材料，热隔离材料和微纳米电子机械系统（MEMS或NEMS）组件。