公开(公告)号：US07803600B2

公开(公告)日：2010-09-28

申请号：US11684806

申请日：2007-03-12

Applicant: Jacobus Alphonsus Josephus Van Dun ,  Walter Boudewijn Leopold Wouters ,  Michel Marie François Janicot ,  Ursula Maria Mocek ,  Jodi Ann Laakso

Inventor： Jacobus Alphonsus Josephus Van Dun ,  Walter Boudewijn Leopold Wouters ,  Michel Marie François Janicot ,  Ursula Maria Mocek ,  Jodi Ann Laakso

IPC: C12N1/20

CPC classification number: A61K31/70 ,  C07D313/00 ,  C07H17/04 ,  C12P17/162 ,  C12R1/29

Abstract: The invention provides a compound of formula (I) and pharmaceutically acceptable salts thereof. Processes for the isolating of this bafilomycin metabolite from a novel Micromonospora species, pharmaceutical compositions containing this metabolite and methods of treatment using said metabolite are also described.

Abstract translation: 本发明提供式（I）化合物及其药学上可接受的盐。 还描述了从新型小单孢菌属物种分离该巴夫洛霉素代谢物的方法，含有该代谢物的药物组合物和使用所述代谢物的治疗方法。

公开(公告)号：US07214705B2

公开(公告)日：2007-05-08

申请号：US10517788

申请日：2003-06-30

Applicant: Jacobus Alphonsus Josephus Van Dun ,  Walter Boudewijn Leopold Wouters ,  Michel Marie François Janicot ,  Ursula Maria Mocek ,  Jodi Ann Laakso

Inventor： Jacobus Alphonsus Josephus Van Dun ,  Walter Boudewijn Leopold Wouters ,  Michel Marie François Janicot ,  Ursula Maria Mocek ,  Jodi Ann Laakso

IPC: A01N43/02 ,  A61K31/335 ,  C07D313/04 ,  C07D313/16

CPC classification number: A61K31/70 ,  C07D313/00 ,  C07H17/04 ,  C12P17/162 ,  C12R1/29

Abstract: The invention provides a compound of formula (I) and pharmaceutically acceptable salts thereof. Processes for the isolating of this bafilomycin metabolite from a novel Micromonospora species, pharmaceutical compositions containing this metabolite and methods of treatment using said metabolite are also described

Abstract translation: 本发明提供式（I）化合物及其药学上可接受的盐。 还描述了用于从新型小单孢菌属物种分离该巴夫洛霉素代谢物的方法，含有该代谢物的药物组合物和使用所述代谢物的治疗方法