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1.发明申请公开(公告)号：US20050095298A1
公开(公告)日：2005-05-05
申请号：US10510655
申请日：2003-04-17
申请人： Hans Gronlund , Johan Ronnelid , Alex Karlsson-Parra , Marianne Van Hage-Hamsten , Rudolf Valenta , Susanne Vrtala , Ursula Wiedermann , Dietrick Kraft
发明人： Hans Gronlund , Johan Ronnelid , Alex Karlsson-Parra , Marianne Van Hage-Hamsten , Rudolf Valenta , Susanne Vrtala , Ursula Wiedermann , Dietrick Kraft
CPC分类号： A61K49/0004 , A61K39/35 , A61K39/36 , A61K47/6927 , A61K2039/6087
摘要： Microparticles are disclosed which comprise a bead essentially consisting of a cross-linked carbohydrate and an antigen covalently linked thereto. The microparticle can be used for the treatment of disorders of the immune system and in diagnostic tests.
摘要翻译： 公开了微粒，其包含基本上由交联的碳水化合物和与其共价连接的抗原组成的珠粒。 微粒可用于治疗免疫系统疾病和诊断测试。
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2.发明申请LACTOBACILLUS PARACASEI NCC2461 (ST11) FOR USE BY PERINATAL MATERNAL ADMINISTRATION IN THE REDUCTION AND PREVENTION OF ALLERGIES IN PROGENY 审中-公开LACTOBACILLUS PARACASEI NCC2461（ST11）用于减少和预防先天性过敏症的临床资料公开(公告)号：US20140037686A1
公开(公告)日：2014-02-06
申请号：US14111844
申请日：2012-04-11
IPC分类号： A61K39/09
CPC分类号： A61K39/09 , A23L33/135 , A23V2002/00 , A61K35/747 , A23V2200/304 , A23V2200/3204 , A23V2250/156 , A23V2250/1872 , A23V2250/1874 , A23V2250/702 , A23V2250/704 , A23V2250/708 , A23V2250/71 , A23V2250/712 , A23V2250/7142
摘要： The present invention provides a probiotic, Lactobacillus paracasei NCC 2461, i.e. ST11, for use by administration to expectant females and/or lactating mothers, and to their progeny for the reduction or prevention of the development of allergic immune responses in progeny. A daily dose of ST11 is administered to a pregnant woman for at least two weeks before delivery and, after delivery, the daily dose of ST11, is administered to the lactating mother or the newborn infant for at least two months, either directly or via the mother's milk. The infant immune responses to allergens are thus reduced, resulting in a “dampened” allergic response. Thus allergy, including atopy, may be prevented in the progeny.
摘要翻译： 本发明提供了益生菌，副干酪乳酸杆菌NCC 2461，即ST11，用于预期雌性和/或哺乳期母亲的施用，以及其后代用于减少或预防后代中过敏免疫反应的发展。 将ST11的日剂量在分娩前至少两周施用给孕妇，并且在分娩后，将ST11的日剂量直接或经由哺乳期母亲或新生儿喂养至少两个月 母乳 因此，对变应原的婴幼儿免疫应答减少，导致“遏制”的过敏反应。 因此，可以在后代中防止包括特应性的变态反应。
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公开(公告)号：US20090269364A1
公开(公告)日：2009-10-29
申请号：US12296738
申请日：2007-04-11
申请人： Christoph Zielinski , Otto Scheiner , Hubert Pehamberger , Heimo Breiteneder , Ursula Wiedermann
发明人： Christoph Zielinski , Otto Scheiner , Hubert Pehamberger , Heimo Breiteneder , Ursula Wiedermann
CPC分类号： A61K39/0011 , A61K2039/545 , A61K2039/55533 , A61K2039/55538 , A61K2039/55544 , A61K2039/55594 , A61K2039/57 , A61K2039/6037 , A61K2039/6081 , A61K2039/627
摘要： The present invention relates to a multi-peptide-multiepitop-vaccine against cancerous diseases associated with HER-2/neu oncogene, i.e. the vaccine comprises a specific combination of peptides presenting different amino acids sequences as occur in the extracellular domain of HER-2/neu protein.
摘要翻译： 本发明涉及针对与HER-2 / neu致癌基因相关的癌性疾病的多肽多表位疫苗，即该疫苗包含在HER-2 / neu致癌基因的细胞外结构域中出现不同氨基酸序列的肽的特异性组合， neu蛋白。
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4.发明授权公开(公告)号：US08454964B2
公开(公告)日：2013-06-04
申请号：US10510655
申请日：2003-04-17
申请人： Hans Groenlund , Johan Roennelid , Alex Karlsson-Parra , Marianne Van Hage-Hamsten , Rudolf Valenta , Susanne Vrtala , Ursula Wiedermann , Dietrich Kraft
发明人： Hans Groenlund , Johan Roennelid , Alex Karlsson-Parra , Marianne Van Hage-Hamsten , Rudolf Valenta , Susanne Vrtala , Ursula Wiedermann , Dietrich Kraft
CPC分类号： A61K49/0004 , A61K39/35 , A61K39/36 , A61K47/6927 , A61K2039/6087
摘要： Microparticles are disclosed which comprise a bead essentially consisting of a cross-linked carbohydrate and an antigen covalently linked thereto. The microparticle can be used for the treatment of disorders of the immune system and in diagnostic tests.
摘要翻译： 公开了微粒，其包含基本上由交联的碳水化合物和与其共价连接的抗原组成的珠粒。 微粒可用于治疗免疫系统疾病和诊断测试。
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