公开(公告)号：US20060127909A1

公开(公告)日：2006-06-15

申请号：US10537449

申请日：2003-12-08

Applicant: Bernd Schwenzer ,  Uta Schmidt ,  Manfred Wirth ,  Kai Kramer ,  Susanne Fussel ,  Axel Meye

Inventor： Bernd Schwenzer ,  Uta Schmidt ,  Manfred Wirth ,  Kai Kramer ,  Susanne Fussel ,  Axel Meye

IPC: A61K48/00 ,  C12Q1/68 ,  C07H21/04

CPC classification number: C12N9/1241

Abstract: The present invention relates to polynucleotides directed towards a gene of a catalytic subunit of human telomerase, as well as to the use of said polynucleotides for the diagnosis, prophylaxis, reduction and follow-up of diseases associated with cell growth, differentiation and/or division, such as tumor diseases.

Abstract translation: 本发明涉及针对人类端粒酶的催化亚基的基因的多核苷酸，以及所述多核苷酸用于诊断，预防，减少和跟踪与细胞生长，分化和/或分裂相关疾病的用途 ，如肿瘤疾病。

公开(公告)号：US20070032440A1

公开(公告)日：2007-02-08

申请号：US10545093

申请日：2004-02-09

Applicant: Axel Meye ,  Susanne Fussel ,  Manfred Wirth ,  Uta Schmidt-Strassbuger ,  Bernd Kuppers ,  Helge Taubert ,  Matthias Kappler ,  Matthias Bache ,  Frank Bartel ,  Peter Wurl

Inventor： Axel Meye ,  Susanne Fussel ,  Manfred Wirth ,  Uta Schmidt-Strassbuger ,  Bernd Kuppers ,  Helge Taubert ,  Matthias Kappler ,  Matthias Bache ,  Frank Bartel ,  Peter Wurl

IPC: A61K48/00 ,  C07H21/04

CPC classification number: C12N15/113 ,  A61K31/7105 ,  A61K31/711 ,  A61K38/00 ,  C12N2310/11 ,  C12N2310/14

Abstract: The present invention relates to oligonucleotides directed against a survivin gene and variants thereof and to the use of said oligonucleotides in the diagnosis, prophylaxis, reduction and follow-up of diseases associated with cell growth, differentiation and/or division, such as tumor diseases.

Abstract translation: 本发明涉及针对存活蛋白基因及其变体的寡核苷酸以及所述寡核苷酸在与细胞生长，分化和/或分裂相关的疾病如肿瘤疾病的诊断，预防，减少和随访中的用途。