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公开(公告)号:US20090293139A1
公开(公告)日:2009-11-26
申请号:US12418403
申请日:2009-04-03
申请人: Jiang Chang , Robert J. Schwartz , Viraj R. Shah
发明人: Jiang Chang , Robert J. Schwartz , Viraj R. Shah
CPC分类号: C12N15/63 , A01K67/0275 , A01K2217/15 , A01K2217/203 , A01K2217/206 , A01K2217/30 , A01K2227/105 , A01K2267/03 , C07K2319/80 , C12N9/6475 , C12N15/8509
摘要: A double-inducible system for expressing a transgene, preferably comprising an RU486-inducible system integrated with a CID-inducible system. The invention further comprises a gene expression system for use in in vitro cell culture studies, and a gene expression expression system for use in engineering modified bigenic mice.
摘要翻译: 用于表达转基因的双诱导系统,优选包含与CID诱导系统整合的RU486诱导系统。 本发明还包括用于体外细胞培养研究的基因表达系统,以及用于工程化修饰的小鼠的基因表达系统。