公开(公告)号：US09164077B2

公开(公告)日：2015-10-20

申请号：US13595648

申请日：2012-08-27

Applicant: Yi-Hsin Lin ,  Wei-Lin Chu ,  Li-Ching Wu

Inventor： Yi-Hsin Lin ,  Wei-Lin Chu ,  Li-Ching Wu

IPC: G01N33/00 ,  G01N33/49 ,  B01L3/00

CPC classification number: G01N33/49 ,  B01L3/502792 ,  B01L2400/0427

Abstract: The present invention discloses a biological detection device and a detecting method. The biological detection device comprises a substrate, an electric field unit, a liquid crystal/polymer composite film (LCPCF), a power supply, a processing unit, and an image sensor. Because of the electrically tunable orientations of the liquid crystal (LC) director anchored among the polymer grains, the wettability of the LCPCF changes with an applied electric field. As a result, we can manipulate a blood droplet on the LCPCF by a wettability gradient owing to the distribution of LC directors on the LCPCF. The motion states of the blood droplet can be related to the various qualities of the blood, and finally determines the health of the test sample. The change of contact angle of blood on LCPCF and the blood droplet motion on LCPCF indicate the concentration of TG and the concentration of HDL.

Abstract translation: 本发明公开了一种生物检测装置和检测方法。 生物检测装置包括基板，电场单元，液晶/聚合物复合膜（LCPCF），电源，处理单元和图像传感器。 由于在聚合物颗粒之间锚定的液晶（LC）导向器的电可调取向，所以LCPCF的润湿性随施加的电场而变化。 因此，由于LC导向器在LCPCF上的分布，我们可以通过润湿梯度来操纵LCPCF上的血滴。 血滴的运动状态可以与血液的各种质量相关，最终确定测试样品的健康状况。 血液对LCPCF的接触角变化和LCPCF上的血滴运动表明TG浓度和HDL浓度。

公开(公告)号：US20130167621A1

公开(公告)日：2013-07-04

申请号：US13595648

申请日：2012-08-27

Applicant: Yi-Hsin LIN ,  Wei-Lin Chu ,  Li-Ching Wu

Inventor： Yi-Hsin LIN ,  Wei-Lin Chu ,  Li-Ching Wu

IPC: G01N33/00

CPC classification number: G01N33/49 ,  B01L3/502792 ,  B01L2400/0427

Abstract: The present invention discloses a biological detection device and a detecting method. The biological detection device comprises a substrate, an electric field unit, a liquid crystal/polymer composite film (LCPCF), a power supply, a processing unit, and an image sensor. Because of the electrically tunable orientations of the liquid crystal (LC) director anchored among the polymer grains, the wettability of the LCPCF changes with an applied electric field. As a result, we can manipulate a blood droplet on the LCPCF by a wettability gradient owing to the distribution of LC directors on the LCPCF. The motion states of the blood droplet can be related to the various qualities of the blood, and finally determines the health of the test sample. The change of contact angle of blood on LCPCF and the blood droplet motion on LCPCF indicate the concentration of TG and the concentration of HDL.

Abstract translation: 本发明公开了一种生物检测装置和检测方法。 生物检测装置包括基板，电场单元，液晶/聚合物复合膜（LCPCF），电源，处理单元和图像传感器。 由于在聚合物颗粒之间锚定的液晶（LC）导向器的电可调取向，所以LCPCF的润湿性随施加的电场而变化。 因此，由于LC导向器在LCPCF上的分布，我们可以通过润湿梯度来操纵LCPCF上的血滴。 血滴的运动状态可以与血液的各种质量相关，最终确定测试样品的健康状况。 血液对LCPCF的接触角变化和LCPCF上的血滴运动表明TG浓度和HDL浓度。