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公开(公告)号：US09155851B2
公开(公告)日：2015-10-13
申请号：US13123714
申请日：2009-10-07
申请人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , Daniel James John , John Trevor Penhallurick , Nicholas Smartt , Nicholas Harrison , William Bakewell
发明人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , Daniel James John , John Trevor Penhallurick , Nicholas Smartt , Nicholas Harrison , William Bakewell
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： An inhaler including an outlet and a plurality of sealed compartments containing medicament is disclosed. An opening mechanism is provided to open the compartment presently aligned with the outlet. An indexing mechanism sequentially aligns the compartments with the outlet. A latch is provided for latching the opening mechanism in an energized position. The latch cannot latch the opening mechanism before the indexing mechanism has aligned the next compartment with the outlet. A method of priming an inhaler and a method of dispensing a medicament from an inhaler is also disclosed.
摘要翻译： 公开了一种包括出口的吸入器和包含药剂的多个密封隔室。 提供打开机构以打开目前与出口对齐的隔间。 分度机构顺序地将隔间与出口对准。 提供了用于将开启机构锁定在通电位置的闩锁。 在分度机构将下一个隔间与出口对准之前，闩锁不能锁定打开机构。 还公开了一种启动吸入器的方法和从吸入器分配药物的方法。
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公开(公告)号：US09289565B2
公开(公告)日：2016-03-22
申请号：US13123140
申请日：2009-10-07
申请人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Trevor John Penhallurick , William Bakewell , Nicholas Harrison
发明人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Trevor John Penhallurick , William Bakewell , Nicholas Harrison
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： The disclosure relates to a medical dispenser, comprising an outlet and a plurality of sealed compartments containing medicament to be sequentially aligned with and dispensed through said outlet. Movement of an actuator sequentially causes mechanical energy to be built up and then released and converted into an indexing movement of the compartments. The disclosure also relates to an indexing method for a medical dispenser.
摘要翻译： 本公开涉及一种医疗分配器，包括出口和多个密封隔室，其包含要顺序地对准并通过所述出口分配的药物。 执行机构的移动顺序地使得机械能被建立，然后释放并转换成隔间的分度运动。 本公开还涉及医用分配器的分度方法。
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公开(公告)号：US09095670B2
公开(公告)日：2015-08-04
申请号：US13129393
申请日：2009-10-07
申请人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Nicholas Smartt , William Bakewell , Nicholas Harrison , Orest Lastow
发明人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Nicholas Smartt , William Bakewell , Nicholas Harrison , Orest Lastow
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0093 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： An inhaler, including a base having at least one air-tight, foil-sealed cavity containing medicament is disclosed. An actuator is engagable with a separating element attached to the foil, the actuator having an energized position in which it is biased towards an unloaded position so as to cause the separating element and attached foil to be moved away from the cavity. A latch has a first position, in which it latches the actuator in said energized position, wherein the latch is at least partly arranged in a flow path such that an inhalation flow through the flow path affects the latch to move from the first position to the second position. A method of dispensing a medicament from a sealed cavity inside an inhaler is also disclosed.
摘要翻译： 公开了一种吸入器，其包括具有至少一个气密的，箔密封腔的含有药物的底座。 致动器可接合附接到箔的分离元件，致动器具有通电位置，在该位置中，致动器被朝向卸载位置偏置，以使分离元件和附着的箔片远离腔体移动。 闩锁具有第一位置，其中致动器在所述通电位置中锁定，其中闩锁至少部分地布置在流动路径中，使得通过流动路径的吸入流动影响闩锁从第一位置移动到 第二名 还公开了一种从吸入器内的密封空腔分配药物的方法。
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公开(公告)号：US20140083422A1
公开(公告)日：2014-03-27
申请号：US13811100
申请日：2011-07-19
申请人： Lars Rune Gustav Arvidsson , William Bakewell , John Phillip Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Orest Lastow , Trevor John Penhallurick , Nicholas Smartt , Märtin Svensson , Björn Ullbrand
发明人： Lars Rune Gustav Arvidsson , William Bakewell , John Phillip Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Orest Lastow , Trevor John Penhallurick , Nicholas Smartt , Märtin Svensson , Björn Ullbrand
CPC分类号： A61M15/0045 , A61M15/0021 , A61M15/0043 , A61M15/0048 , A61M15/0075 , A61M15/0081 , A61M15/0091 , A61M15/08 , A61M2202/064
摘要： A dry powder inhaler comprises a disc-shaped assembly (14) having cavities (16) filled with medicament powder for inhalation. The assembly is rotatably mounted in a housing (6, 8) on which is mounted a rotatable external casing (11, 12). A mouthpiece (10) is movably mounted on the housing (6, 8) allowing it to be brought into and out of engagement with the edge of the disc (14) whereby the mouthpiece acts as a brake to prevent or permit rotational movement of the disc (14). The inhaler is opened by rotating the housing with respect to the casing (11, 12) to expose the mouthpiece (10). As the inhaler is opened and closed, cam followers (105) on the mouthpiece move along cam tracks (109) in the casing (11, 12), causing the mouthpiece to move against or away from the disc (14). A gap is defined between the disc and mouthpiece to allow a flow of bypass air to enter the mouthpiece.
摘要翻译： 干粉吸入器包括具有填充有用于吸入的药物粉末的空腔（16）的盘形组件（14）。 组件可旋转地安装在壳体（6,8）中，其上安装有可旋转的外壳（11,12）。 吸嘴（10）可移动地安装在壳体（6,8）上，允许其与盘（14）的边缘进入和离开接合，由此接口作为制动器来防止或允许 光盘（14）。 通过相对于壳体（11,12）旋转壳体来打开吸入器以暴露接口（10）。 当吸入器打开和关闭时，口部上的凸轮从动件（105）沿壳体（11,12）中的凸轮轨道（109）移动，使得接口件能够抵靠或远离盘片（14）移动。 在盘和接口之间限定间隙，以允许旁路空气流进入接口。
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公开(公告)号：US20120125330A1
公开(公告)日：2012-05-24
申请号：US13129393
申请日：2009-10-07
申请人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Nicholas Smartt , William Bakewell , Nicholas Harrison , Orest Lastow
发明人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Nicholas Smartt , William Bakewell , Nicholas Harrison , Orest Lastow
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0093 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： The present invention relates to an inhaler, comprising a base having at least one air-tight, foil-sealed cavity containing medicament. An actuator is engagable with a separating element attached to the foil, the actuator having an energized position in which it is biased towards an unloaded position so as to cause the separating element and attached foil to be moved away from the cavity. A latch has a first position, in which it latches the actuator in said energized position, wherein the latch is at least partly arranged in a flow path such that an inhalation flow through the flow path affects the latch to move from the first position to the second position. The invention also relates to a method of dispensing a medicament from a sealed cavity inside an inhaler.
摘要翻译： 吸入器技术领域本发明涉及一种吸入器，其包括具有至少一个包含药物的气密的箔密封空腔的底座。 致动器可接合附接到箔的分离元件，致动器具有通电位置，在该位置中，致动器被朝向卸载位置偏置，以使分离元件和附着的箔片远离腔体移动。 闩锁具有第一位置，其中致动器在所述通电位置中锁定，其中闩锁至少部分地布置在流动路径中，使得通过流动路径的吸入流动影响闩锁从第一位置移动到 第二名 本发明还涉及从吸入器内部的密封空腔分配药物的方法。
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公开(公告)号：US20140000601A1
公开(公告)日：2014-01-02
申请号：US13811104
申请日：2011-07-19
申请人： Lars Rune Gustav Arvidsson , William Bakewell , Patrick Campbell , Christopher Groombridge , James Daniel John , Jan Olof Bertil Lundgren , Camilla Lundstrom , Mårten Rittfeldt , Jonas Svennberg
发明人： Lars Rune Gustav Arvidsson , William Bakewell , Patrick Campbell , Christopher Groombridge , James Daniel John , Jan Olof Bertil Lundgren , Camilla Lundstrom , Mårten Rittfeldt , Jonas Svennberg
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0021 , A61M15/0043 , A61M15/0048 , A61M15/0075 , A61M15/0081 , A61M2202/064
摘要： A dry powder inhaler (2) comprises a housing (6, 8) including a mouthpiece (10) and a cover (11, 12) movably mounted to the housing (6, 8). The cover (11, 12) is movable between an open configuration of the inhaler (2) in which the mouthpiece (10) is exposed for use and a closed configuration of the inhaler (2) in which the mouthpiece (10) is enclosed. In the open position, the cover (11, 12) at least partly defines an inlet aperture (71) to an inhalation air flow path leading through the inhaler (2) and communicating with the mouthpiece (10). The inlet aperture (71) is positioned in such a way that makes it difficult for a user to obstruct it when using the inhaler (2). Preferably, in the closed position, the mouthpiece (10) is received into the inlet aperture (71) to protect the mouthpiece (10) when the inhaler (2) is stored.
摘要翻译： 干粉吸入器（2）包括壳体（6,8），其包括接口（10）和可移动地安装到壳体（6,8）的盖子（11,12）。 所述盖子（11,12）可以在所述吸嘴（2）的打开构型（其中所述接口）暴露于所述吸入器的使用状态和所述吸入器（2）的封闭构造之间移动。 在打开位置，盖（11,12）至少部分地限定到通过吸入器（2）并与接口（10）连通的吸入空气流动通道的入口孔（71）。 入口孔71以这样的方式定位，使得当使用吸入器（2）时使用者难以阻挡入口孔71。 优选地，在关闭位置，吸嘴（10）被容纳在入口孔（71）中以在吸入器（2）被储存时保护接口管10。
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公开(公告)号：US20120048272A1
公开(公告)日：2012-03-01
申请号：US13123714
申请日：2009-10-07
申请人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , Daniel James John , John Trevor Penhallurick , Nicholas Smartt , Nicholas Harrison , William Bakewell
发明人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , Daniel James John , John Trevor Penhallurick , Nicholas Smartt , Nicholas Harrison , William Bakewell
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： The disclosure relates to an inhaler, comprising an outlet and a plurality of sealed compartments containing medicament. An opening mechanism is provided to open the compartment presently aligned with the outlet. An indexing mechanism sequentially aligns the compartments with the outlet. A latch is provided for latching the opening mechanism in an energized position. The latch cannot latch the opening mechanism before the indexing mechanism has aligned the next compartment with the outlet. The disclosure also relates to a method of priming an inhaler and a method of dispensing a medicament from an inhaler.
摘要翻译： 本公开涉及一种吸入器，其包括出口和包含药物的多个密封隔室。 提供打开机构以打开目前与出口对齐的隔间。 分度机构顺序地将隔间与出口对准。 提供了用于将开启机构锁定在通电位置的闩锁。 在分度机构将下一个隔间与出口对准之前，闩锁不能锁定打开机构。 本公开还涉及一种起动吸入器的方法和从吸入器分配药物的方法。
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公开(公告)号：US20110259326A1
公开(公告)日：2011-10-27
申请号：US13123140
申请日：2009-10-07
申请人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Trevor John Penhallurick , William Bakewell , Nicholas Harrison
发明人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , Trevor John Penhallurick , William Bakewell , Nicholas Harrison
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： The disclosure relates to a medical dispenser, comprising an outlet and a plurality of sealed compartments containing medicament to be sequentially aligned with and dispensed through said outlet. Movement of an actuator sequentially causes mechanical energy to be built up and then released and converted into an indexing movement of the compartments. The disclosure also relates to an indexing method for a medical dispenser.
摘要翻译： 本公开涉及一种医疗分配器，包括出口和多个密封隔室，其包含要顺序地对准并通过所述出口分配的药物。 执行机构的移动顺序地使得机械能被建立，然后释放并转换成隔间的分度运动。 本公开还涉及医用分配器的分度方法。
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公开(公告)号：US20110253138A1
公开(公告)日：2011-10-20
申请号：US13123105
申请日：2009-10-07
申请人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , William Bakewell , Nicholas Harrison
发明人： John Briant , Patrick Campbell , Charles Cooke , Christopher Groombridge , James Daniel John , William Bakewell , Nicholas Harrison
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0075 , A61M15/0096 , A61M2202/064 , A61M2205/073 , A61M2205/581
摘要： The disclosure relates to an inhaler comprising an outlet through which doses of medicament may be dispensed. The inhaler also comprises a dispensing mechanism having a primed state, in which it is ready for dispensing a dose, and a fired state, in which it has dispensed a dose. In one aspect, the inhaler also comprises a disabler which, after the final dose has been dispensed, is activated to disable the dispensing mechanism from generating a sound which has been audible when the dispensing mechanism has moved from its primed state to its fired state. In a second aspect, the disabler prevents the dispensing mechanism from being in its primed state when an outlet cover is in an open position, whereby a not ready indication is presented to the user.
摘要翻译： 本公开涉及一种吸入器，其包括可以分配剂量的药物的出口。 吸入器还包括具有底漆状态的分注机构，其中其准备好分配剂量，并且其已经分配剂量的烧制状态。 在一个方面，吸入器还包括消除器，其在最终剂量被分配之后被激活，以使得分配机构不能产生当分配机构已经从其引发状态移动到其被发射状态时已被听到的声音。 在第二方面，当出口盖处于打开位置时，消除器防止分配机构处于其初始化状态，从而向用户呈现未就绪的指示。
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