Antifungal nail coat and method of use
    3.
    发明申请
    Antifungal nail coat and method of use 失效
    抗真菌指甲外套及使用方法

    公开(公告)号:US20060067898A1

    公开(公告)日:2006-03-30

    申请号:US10514190

    申请日:2004-03-22

    IPC分类号: A61K31/137 A61K8/41

    摘要: A dual action antifungal nail coat composition and method of use for ameliorating or preventing fungal infection of the nails, and onychomycosis, in particular, is disclosed. Composition embodiments in the form of one-coat type and two-coat type suitable for daily fungicidal regimens are disclosed. A preferred antifungal nail coat composition comprises an effective fungicidal amount of antifungal agent, a permeation enhancing amount of a substantially non-volatile, permeation enhancer, a film-forming amount of a hydrophilic polymer, and a pharmaceutically acceptable, volatile carrier. The composition provides a substantially water-soluble fungicidal coating on contacting a fungally susceptible or infected nail.

    摘要翻译: 公开了一种双作用抗真菌指甲油组合物和用于改善或预防指甲真菌感染和甲真菌病的用途的方法。 公开了适用于日常杀真菌方案的单涂层型和双层型形式的组合物实施方案。 优选的抗真菌指甲涂层组合物包含有效杀真菌量的抗真菌剂,渗透促进量的基本上不挥发的渗透促进剂,成膜量的亲水性聚合物和药学上可接受的挥发性载体。 组合物在接触真菌感染或感染的指甲时提供基本上水溶性的杀真菌涂层。