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8 条记录 (耗时 0.019 秒)

    Double bellow occluder for sclerotherapy
    5.
    发明授权
    Double bellow occluder for sclerotherapy 有权

    公开(公告)号：US10022127B2

    公开(公告)日：2018-07-17

    申请号：US13287215

    申请日：2011-11-02

    申请人： Wouter Erik Roorda ,  Michael Green ,  Neil Burkhart

    发明人： Wouter Erik Roorda ,  Michael Green ,  Neil Burkhart

    IPC分类号： A61M25/00 ,  A61B17/12 ,  A61M25/10

    摘要： The disclosed subject matter describes systems and methods of delivering a therapeutic agent, such as a sclerosing agent, to the walls of a blood vessel to perform sclerotherapy. In an exemplary embodiment a catheter includes a guidewire catheter having at least one guidewire lumen extending therethrough and a slidable concentric tube disposed over the guidewire catheter. At least one bellow is coupled to the concentric tube and configured for conversion between an unexpanded and expanded configuration wherein movement of the concentric tube in a first direction causes the at least one bellow to expand and movement of the concentric tube in a second direction causes the at least one bellow to contract. Additionally, the concentric tube contains at least one port for delivery of a therapeutic agent, e.g. a sclerosing agent. The at least one bellow expands and contracts via mechanical forces.

    Zwitterionic terpolymers, method of making and use on medical devices
    6.
    发明授权
    Zwitterionic terpolymers, method of making and use on medical devices 失效
    两性离子三元共聚物，制造和使用在医疗器械上的方法

    公开(公告)号：US07713541B1

    公开(公告)日：2010-05-11

    申请号：US11939512

    申请日：2007-11-13

    申请人： Stephen Pacetti ,  Wouter Erik Roorda

    发明人： Stephen Pacetti ,  Wouter Erik Roorda

    IPC分类号： A61F2/02

    CPC分类号： C08F230/02 ,  A61F2/91 ,  A61L27/34 ,  A61L31/10 ,  C08F2220/1825 ,  C08F2220/282 ,  C09D133/14 ,  C08L33/14 ,  C08F220/36

    摘要： Biocompatible terpolymers are manufactured to include a zwitterionic monomer, an alkoxy acrylate monomer, and a hydrophobic monomer. The alkoxy acrylate monomer can be a 2-methoxyethyl methacrylate (MOEMA) or a 2-methoxyethyl methacrylate (EOEMA). Alternatively, the alkoxy acrylate can be 2-methoxyethyl acrylate (MOEA) or 2-methoxyethyl acrylate (EOEA). The alkoxy acrylate monomers advantageously give the zwitterionic copolymers greater ductility, strength, and toughness while maintaining a desired amount of hydrophilicity. The improved toughness allows the zwitterionic copolymers to be processed without cross-linking, which improves the elongation properties of the zwitterionic copolymer, and reduces the risk of cracking during use.

    摘要翻译： 制备生物相容性三元共聚物以包括两性离子单体，烷氧基丙烯酸酯单体和疏水性单体。 烷氧基丙烯酸酯单体可以是甲基丙烯酸2-甲氧基乙酯（MOEMA）或甲基丙烯酸2-甲氧基乙酯（EOEMA）。 或者，烷氧基丙烯酸酯可以是丙烯酸2-甲氧基乙酯（MOEA）或丙烯酸2-甲氧基乙酯（EOEA）。 烷氧基丙烯酸酯单体有利地使两性离子共聚物具有更高的延展性，强度和韧性，同时保持所需量的亲水性。 改进的韧性使得两性离子共聚物在不交联的情况下进行加工，这提高了两性离子共聚物的伸长性能，并降低了使用过程中的开裂风险。

    Refillable implantable drug delivery pump
    7.
    发明授权
    Refillable implantable drug delivery pump 有权
    可补充的可植入药物输送泵

    公开(公告)号：US06283949B1

    公开(公告)日：2001-09-04

    申请号：US09472656

    申请日：1999-12-27

    申请人： Wouter Erik Roorda

    发明人： Wouter Erik Roorda

    IPC分类号： A61M100

    CPC分类号： A61M5/14276 ,  A61M5/14232 ,  Y10S128/12

    摘要： An implantable drug delivery pump includes a reservoir, a dispensing chamber adjacent to the reservoir, a dispensing passage provided along an interior surface of the dispensing chamber, and an actuator for applying a moving compressive force onto the dispensing passage. The pump is subcutaneously implantable in a patient, and a drug is injected into the reservoir through a septum provided on a housing for the reservoir. As the compressive force applied by the actuator moves along the dispensing passage, the drug preparation is simultaneously pushed out of the dispensing passage into a catheter for delivery to the desired site, and additional drug preparation is drawn into the dispensing passage from the reservoir. The actuator includes a rotating arm driven by an motor at a controllable rate.

    摘要翻译： 可植入药物输送泵包括储存器，与储存器相邻的分配室，沿着分配室的内表面设置的分配通道，以及用于将分离通道上施加移动的压缩力的致动器。 泵可皮下植入患者体内，并通过设置在储存器的壳体上的隔膜将药物注入储存器。 当由致动器施加的压缩力沿着分配通道移动时，药物制剂同时从分配通道推出到导管中以输送到期望的位置，并且另外的药物制剂从储存器被吸入分配通道。 致动器包括以可控速率由马达驱动的旋转臂。

    DOUBLE BELLOW OCCLUDER FOR SCLEROTHERAPY
    8.
    发明申请
    DOUBLE BELLOW OCCLUDER FOR SCLEROTHERAPY 有权
    双重BELLOW OCCLUDER为SCLEROTHERAPY

    公开(公告)号：US20130110081A1

    公开(公告)日：2013-05-02

    申请号：US13287215

    申请日：2011-11-02

    申请人： Wouter Erik Roorda ,  Michael Green ,  Neil Burkhart

    发明人： Wouter Erik Roorda ,  Michael Green ,  Neil Burkhart

    IPC分类号： A61M29/02

    CPC分类号： A61B17/12022 ,  A61B17/12136 ,  A61B17/12186 ,  A61B2017/12004 ,  A61B2017/1205 ,  A61B2218/002 ,  A61B2218/007 ,  A61M25/00 ,  A61M25/1011 ,  A61M2025/0004 ,  A61M2025/1052

    摘要： The disclosed subject matter describes systems and methods of delivering a therapeutic agent, such as a sclerosing agent, to the walls of a blood vessel to perform sclerotherapy. In an exemplary embodiment a catheter includes a guidewire catheter having at least one guidewire lumen extending therethrough and a slidable concentric tube disposed over the guidewire catheter. At least one bellow is coupled to the concentric tube and configured for conversion between an unexpanded and expanded configuration wherein movement of the concentric tube in a first direction causes the at least one bellow to expand and movement of the concentric tube in a second direction causes the at least one bellow to contract. Additionally, the concentric tube contains at least one port for delivery of a therapeutic agent, e.g. a sclerosing agent. The at least one bellow expands and contracts via mechanical forces.

    摘要翻译： 所公开的主题描述了将治疗剂（例如硬化剂）递送到血管的壁以进行硬化疗法的系统和方法。 在示例性实施例中，导管包括导丝导管，其具有延伸穿过其中的至少一个导丝管腔和设置在导丝导管上的可滑动的同心管。 至少一个波纹管耦合到同心管并且构造成用于在未膨胀和膨胀构型之间转换，其中同心管在第一方向上的运动使得至少一个波纹管膨胀并且同心管在第二方向上的移动导致 至少有一个合同。 另外，同心管包含用于递送治疗剂的至少一个端口，例如， 硬化剂。 至少一个波纹管通过机械力膨胀和收缩。