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1.发明授权Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia 有权用于治疗不规则心室收缩的方法和装置，例如在心房心律失常期间公开(公告)号：US08064997B2
公开(公告)日：2011-11-22
申请号：US11423516
申请日：2006-06-12
IPC分类号： A61N1/362
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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2.发明申请METHOD AND APPARATUS FOR TREATING IRREGULAR VENTRICULAR CONTRACTIONS SUCH AS DURING ATRIAL ARRHYTHMIA 有权方法和装置，用于治疗非正常血管造影，如阿司匹林公开(公告)号：US20090076563A1
公开(公告)日：2009-03-19
申请号：US12325887
申请日：2008-12-01
IPC分类号： A61N1/368
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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3.发明申请METHOD AND APPARATUS FOR TREATING IRREGULAR VENTRICULAR CONTRACTIONS SUCH AS DURING ATRIAL ARRHYTHMIA 有权方法和装置，用于治疗非正常血管造影，如阿司匹林公开(公告)号：US20070016258A1
公开(公告)日：2007-01-18
申请号：US11423516
申请日：2006-06-12
申请人： David Krig , Jesse Hartley , Wyatt Stahl , Jeffrey Stahmann
发明人： David Krig , Jesse Hartley , Wyatt Stahl , Jeffrey Stahmann
IPC分类号： A61N1/00
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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公开(公告)号：US07460908B2
公开(公告)日：2008-12-02
申请号：US10852602
申请日：2004-05-24
IPC分类号： A61N1/362
CPC分类号： A61N1/3962 , A61N1/3621 , A61N1/3627 , A61N1/3682 , A61N1/395 , A61N1/3987
摘要： A cardiac rhythm management system includes techniques for computing an indicated pacing interval, AV delay, or other timing interval. In one embodiment, a variable indicated pacing interval is computed based at least in part on an underlying intrinsic heart rate. The indicated pacing interval is used to time the delivery of biventricular coordination therapy even when ventricular heart rates are irregular, such as in the presence of atrial fibrillation. In another embodiment, a variable filter indicated AV interval is computed based at least in part on an underlying intrinsic AV interval. The indicated AV interval is used to time the delivery of atrial tracking biventricular coordination therapy when atrial heart rhythms are not arrhythmic. Other indicated timing intervals may be similarly determined. The indicated pacing interval, AV delay, or other timing interval can also be used in combination with a sensor indicated rate indicator.
摘要翻译： 心律管理系统包括用于计算指示的起搏间隔，AV延迟或其它定时间隔的技术。 在一个实施例中，至少部分地基于潜在的内在心率来计算变量指示的起搏间隔。 即使在室性心率不规则的情况下，例如在心房纤维性颤动的存在下，指示的起搏间隔也用于给双心室协调治疗的时间。 在另一个实施例中，至少部分地基于潜在的固有AV间隔来计算指示AV间隔的可变滤波器。 指示的AV间隔用于在心房心律不是心律不齐的时候交付心房跟踪双心室协调治疗。 可以类似地确定其他指示的定时间隔。 指示的起搏间隔，AV延迟或其他定时间隔也可以与传感器指示的速率指示器组合使用。
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5.发明授权Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia 有权用于治疗不规则心室收缩的方法和装置，例如在心房心律失常期间公开(公告)号：US07062325B1
公开(公告)日：2006-06-13
申请号：US09316515
申请日：1999-05-21
IPC分类号： A61N1/362
CPC分类号： A61N1/3962 , A61N1/3621 , A61N1/3627 , A61N1/3682 , A61N1/395 , A61N1/3987
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V—V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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6.发明授权Cardiac rhythm management device with detection and therapy for sudden syncopal events 有权心脏节律管理装置具有突发性突发事件的检测和治疗
公开(公告)号：US6049735A
公开(公告)日：2000-04-11
申请号：US259349
申请日：1999-03-01
申请人： Jesse W. Hartley , Wyatt Stahl , John Voegele
发明人： Jesse W. Hartley , Wyatt Stahl , John Voegele
CPC分类号： A61N1/36521
摘要： A method and apparatus for cardiac stimulation for addressing vasovagal syncope incorporates a detection algorithm in which a precipitous rate drop from a pre-existing average intrinsic heart rate value to a lower rate limit is sensed and if the patient is awake and the intrinsic rate remains below the lower rate limit for a predetermined number of beats, the patient's heart is paced at a rate that is a programmed differential above the prior average intrinsic rate for a second programmed time interval, at the conclusion of which the pacing rate is gradually decreased to the average heart rate existing prior to the sudden rate drop or to the lower rate limit.
摘要翻译： 用于心脏刺激的用于解决血管迷走性晕厥的方法和装置包括检测算法，其中从先前存在的平均内在心率值到较低速率极限的急剧下降速率被检测到，并且如果患者清醒并且内在速率保持在低于 对于预定次数的节拍的较低速率限制，患者的心脏以相对于第二编程时间间隔的先前平均固有频率高于程序差速率的速率进行起搏，其结束时起搏速率逐渐降低至 在突然率下降之前存在的平均心率或下限率。
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公开(公告)号：US08135465B2
公开(公告)日：2012-03-13
申请号：US12325887
申请日：2008-12-01
IPC分类号： A61N1/365
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system includes techniques for computing an indicated pacing interval, AV delay, or other timing interval. In one embodiment, a variable indicated pacing interval is computed based at least in part on an underlying intrinsic heart rate. The indicated pacing interval is used to time the delivery of biventricular coordination therapy even when ventricular heart rates are irregular, such as in the presence of atrial fibrillation. In another embodiment, a variable filter indicated AV interval is computed based at least in part on an underlying intrinsic AV interval. The indicated AV interval is used to time the delivery of atrial tracking biventricular coordination therapy when atrial heart rhythms are not arrhythmic. Other indicated timing intervals may be similarly determined. The indicated pacing interval, AV delay, or other timing interval can also be used in combination with a sensor indicated rate indicator.
摘要翻译： 心律管理系统包括用于计算指示的起搏间隔，AV延迟或其它定时间隔的技术。 在一个实施例中，至少部分地基于潜在的内在心率来计算变量指示的起搏间隔。 即使在室性心率不规则的情况下，例如在心房纤维性颤动的存在下，指示的起搏间隔也用于给双心室协调治疗的时间。 在另一个实施例中，至少部分地基于潜在的固有AV间隔来计算指示AV间隔的可变滤波器。 指示的AV间隔用于在心房心律不是心律不齐的时候交付心房跟踪双心室协调治疗。 可以类似地确定其他指示的定时间隔。 指示的起搏间隔，AV延迟或其他定时间隔也可以与传感器指示的速率指示器组合使用。
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