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1.发明授权Cardiac rhythm management device with detection and therapy for sudden syncopal events 有权心脏节律管理装置具有突发性突发事件的检测和治疗
公开(公告)号：US6049735A
公开(公告)日：2000-04-11
申请号：US259349
申请日：1999-03-01
申请人： Jesse W. Hartley , Wyatt Stahl , John Voegele
发明人： Jesse W. Hartley , Wyatt Stahl , John Voegele
CPC分类号： A61N1/36521
摘要： A method and apparatus for cardiac stimulation for addressing vasovagal syncope incorporates a detection algorithm in which a precipitous rate drop from a pre-existing average intrinsic heart rate value to a lower rate limit is sensed and if the patient is awake and the intrinsic rate remains below the lower rate limit for a predetermined number of beats, the patient's heart is paced at a rate that is a programmed differential above the prior average intrinsic rate for a second programmed time interval, at the conclusion of which the pacing rate is gradually decreased to the average heart rate existing prior to the sudden rate drop or to the lower rate limit.
摘要翻译： 用于心脏刺激的用于解决血管迷走性晕厥的方法和装置包括检测算法，其中从先前存在的平均内在心率值到较低速率极限的急剧下降速率被检测到，并且如果患者清醒并且内在速率保持在低于 对于预定次数的节拍的较低速率限制，患者的心脏以相对于第二编程时间间隔的先前平均固有频率高于程序差速率的速率进行起搏，其结束时起搏速率逐渐降低至 在突然率下降之前存在的平均心率或下限率。
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公开(公告)号：US07460908B2
公开(公告)日：2008-12-02
申请号：US10852602
申请日：2004-05-24
IPC分类号： A61N1/362
CPC分类号： A61N1/3962 , A61N1/3621 , A61N1/3627 , A61N1/3682 , A61N1/395 , A61N1/3987
摘要： A cardiac rhythm management system includes techniques for computing an indicated pacing interval, AV delay, or other timing interval. In one embodiment, a variable indicated pacing interval is computed based at least in part on an underlying intrinsic heart rate. The indicated pacing interval is used to time the delivery of biventricular coordination therapy even when ventricular heart rates are irregular, such as in the presence of atrial fibrillation. In another embodiment, a variable filter indicated AV interval is computed based at least in part on an underlying intrinsic AV interval. The indicated AV interval is used to time the delivery of atrial tracking biventricular coordination therapy when atrial heart rhythms are not arrhythmic. Other indicated timing intervals may be similarly determined. The indicated pacing interval, AV delay, or other timing interval can also be used in combination with a sensor indicated rate indicator.
摘要翻译： 心律管理系统包括用于计算指示的起搏间隔，AV延迟或其它定时间隔的技术。 在一个实施例中，至少部分地基于潜在的内在心率来计算变量指示的起搏间隔。 即使在室性心率不规则的情况下，例如在心房纤维性颤动的存在下，指示的起搏间隔也用于给双心室协调治疗的时间。 在另一个实施例中，至少部分地基于潜在的固有AV间隔来计算指示AV间隔的可变滤波器。 指示的AV间隔用于在心房心律不是心律不齐的时候交付心房跟踪双心室协调治疗。 可以类似地确定其他指示的定时间隔。 指示的起搏间隔，AV延迟或其他定时间隔也可以与传感器指示的速率指示器组合使用。
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3.发明授权Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia 有权用于治疗不规则心室收缩的方法和装置，例如在心房心律失常期间公开(公告)号：US08064997B2
公开(公告)日：2011-11-22
申请号：US11423516
申请日：2006-06-12
IPC分类号： A61N1/362
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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4.发明申请METHOD AND APPARATUS FOR TREATING IRREGULAR VENTRICULAR CONTRACTIONS SUCH AS DURING ATRIAL ARRHYTHMIA 有权方法和装置，用于治疗非正常血管造影，如阿司匹林公开(公告)号：US20090076563A1
公开(公告)日：2009-03-19
申请号：US12325887
申请日：2008-12-01
IPC分类号： A61N1/368
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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公开(公告)号：US08135465B2
公开(公告)日：2012-03-13
申请号：US12325887
申请日：2008-12-01
IPC分类号： A61N1/365
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system includes techniques for computing an indicated pacing interval, AV delay, or other timing interval. In one embodiment, a variable indicated pacing interval is computed based at least in part on an underlying intrinsic heart rate. The indicated pacing interval is used to time the delivery of biventricular coordination therapy even when ventricular heart rates are irregular, such as in the presence of atrial fibrillation. In another embodiment, a variable filter indicated AV interval is computed based at least in part on an underlying intrinsic AV interval. The indicated AV interval is used to time the delivery of atrial tracking biventricular coordination therapy when atrial heart rhythms are not arrhythmic. Other indicated timing intervals may be similarly determined. The indicated pacing interval, AV delay, or other timing interval can also be used in combination with a sensor indicated rate indicator.
摘要翻译： 心律管理系统包括用于计算指示的起搏间隔，AV延迟或其它定时间隔的技术。 在一个实施例中，至少部分地基于潜在的内在心率来计算变量指示的起搏间隔。 即使在室性心率不规则的情况下，例如在心房纤维性颤动的存在下，指示的起搏间隔也用于给双心室协调治疗的时间。 在另一个实施例中，至少部分地基于潜在的固有AV间隔来计算指示AV间隔的可变滤波器。 指示的AV间隔用于在心房心律不是心律不齐的时候交付心房跟踪双心室协调治疗。 可以类似地确定其他指示的定时间隔。 指示的起搏间隔，AV延迟或其他定时间隔也可以与传感器指示的速率指示器组合使用。
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6.发明授权Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia 有权用于治疗不规则心室收缩的方法和装置，例如在心房心律失常期间公开(公告)号：US07062325B1
公开(公告)日：2006-06-13
申请号：US09316515
申请日：1999-05-21
IPC分类号： A61N1/362
CPC分类号： A61N1/3962 , A61N1/3621 , A61N1/3627 , A61N1/3682 , A61N1/395 , A61N1/3987
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V—V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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公开(公告)号：US08900154B2
公开(公告)日：2014-12-02
申请号：US11136195
申请日：2005-05-24
申请人： Jeffrey E. Stahmann , Quan Ni , Jesse W. Hartley
发明人： Jeffrey E. Stahmann , Quan Ni , Jesse W. Hartley
CPC分类号： A61B5/0537 , A61B5/0538 , A61N1/3627 , A61N1/365 , A61N2001/0585
摘要： This patent document discusses, among other things, systems, devices, and methods for predicting an occurrence of impending thoracic fluid accumulation and in one example, invoking a responsive therapy, such as to prevent or minimize the consequences of the impending thoracic fluid accumulation. One example of the present systems, devices, and methods senses or receives at least one parameter that is statistically associated with impending thoracic fluid accumulation from a subject. Using such parameter(s), a probability of impending thoracic fluid accumulation is estimated. A list of parameters determines which values are recurrently sensed or received at various desired time intervals. Another example of the present systems, devices, and methods weights the sensed or received parameter value(s) to compute the probability estimate of impending thoracic fluid accumulation. A responsive preventive thoracic fluid accumulation therapy or other therapy is selected and activated using the probability estimate of impending thoracic fluid accumulation.
摘要翻译： 该专利文献尤其涉及用于预测即将到来的胸腔积液的发生的系统，装置和方法，并且在一个示例中，引用响应性治疗，例如防止或最小化即将到来的胸腔积液的后果。 本系统，装置和方法的一个示例感测或接收至少一个与来自受试者的即将到来的胸腔积液相关联的参数。 使用这样的参数，估计即将到来的胸腔积液的概率。 参数列表确定以各种期望的时间间隔反复感测或接收哪些值。 本系统，装置和方法的另一个例子对感测或接收的参数值进行加权，以计算即将到来的胸腔积液的概率估计。 使用即将到来的胸腔积液的概率估计来选择和激活反应性预防性胸腔积液治疗或其他治疗。
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8.发明授权Method and apparatus for control of cardiac therapy using non-invasive hemodynamic sensor 有权使用非侵入性血液动力学传感器控制心脏治疗的方法和装置公开(公告)号：US08798747B2
公开(公告)日：2014-08-05
申请号：US13273108
申请日：2011-10-13
IPC分类号： A61N1/00
CPC分类号： A61N1/36557 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61N1/36114 , A61N1/36564
摘要： A cardiac rhythm management (CRM) system includes a non-invasive hemodynamic sensing device and an implantable medical device to sense a hemodynamic signal and derive one or more cardiac performance parameters from the hemodynamic signal. The non-invasive hemodynamic sensing device includes at least a portion configured for external attachment to a body in which the implantable medical device is implanted. The one or more cardiac performance parameters are used for various diagnostic, monitoring, and therapy control purposes.
摘要翻译： 心律管理（CRM）系统包括非侵入性血液动力学感测装置和可植入医疗装置，用于感测血液动力学信号并从血流动力学信号导出一个或多个心脏性能参数。 非侵入式血流动力学检测装置包括至少一部分，其构造成用于外部附接到其中植入可植入医疗装置的主体。 一个或多个心脏性能参数用于各种诊断，监测和治疗控制目的。
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公开(公告)号：US08515535B2
公开(公告)日：2013-08-20
申请号：US12695895
申请日：2010-01-28
IPC分类号： A61N1/00
CPC分类号： A61B5/686 , A61B5/0022 , A61B5/0024 , A61B5/02028 , A61B5/0205 , A61B5/04012 , A61B5/0402 , A61B5/076 , A61B5/0809 , A61B5/0816 , A61B5/0826 , A61B5/085 , A61B5/091 , A61B5/1118 , A61B5/4836 , A61B5/7275 , A61B5/7282 , A61B5/746 , A61B5/747 , A61N1/3627 , A61N1/36585 , A61N1/3702 , A61N1/3987 , G06F19/00 , G16H50/20 , G16H50/30
摘要： Cardiac monitoring and/or stimulation methods and systems employing dyspnea measurement. An implantable cardiac device may sense transthoracic impedance and determine a patient activity level. An index indicative of pulmonary function is implantably computed to detect an episode of dyspnea based on a change, trend, and/or value exceeding a threshold at a determined patient activity level. Trending one or more pulmonary function index values may be done to determine a patient's pulmonary function index profile, which may be used to adapt a cardiac therapy. A physician may be automatically alerted in response to a pulmonary function index value and/or a trend of the patient's pulmonary index being beyond a threshold. Computed pulmonary function index values and their associated patient's activity levels may be stored periodically in a memory and/or transmitted to a patient-external device.
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公开(公告)号：US08323204B2
公开(公告)日：2012-12-04
申请号：US12403880
申请日：2009-03-13
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Quan Ni , Kent Lee
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Quan Ni , Kent Lee
CPC分类号： A61B5/0803 , A61B5/02405 , A61N1/3601
摘要： An event-based approach to collecting and organizing information associated with events affecting respiration is presented. The detection or prediction of an event affecting the respiration of a patient initiates acquisition of information associated with the event. The respiratory logbook system acquires information associated with the event during the event and during intervals proximate in time to the event. The information is organized as a respiratory log entry. The user can access the information by operating a user interface. The information may be presented in textual or graphical form.
摘要翻译： 提出了一种基于事件的方法来收集和组织与影响呼吸的事件相关的信息。 影响患者呼吸的事件的检测或预测启动与事件相关联的信息的获取。 呼吸记录系统在事件期间以及在时间上接近事件的间隔期间获取与事件相关联的信息。 信息被组织为呼吸日志条目。 用户可以通过操作用户界面访问信息。 信息可以以文本或图形形式呈现。
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