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公开(公告)号:US20060204501A1
公开(公告)日:2006-09-14
申请号:US10564302
申请日:2005-03-09
申请人: Kiyohiko Hatake , Yasuhito Terui , Yuji Mishima , Akio Yamada , Takuma Sakurai , Takehito Itoh
发明人: Kiyohiko Hatake , Yasuhito Terui , Yuji Mishima , Akio Yamada , Takuma Sakurai , Takehito Itoh
IPC分类号: A61K39/395 , A61K38/40
摘要: A lactoferrin hydrolysate mixture or lactoferrin partial peptide that can be obtained by hydrolyzing lactoferrin with a hydrolytic enzyme and has an action of enhancing cytotoxic activity of an antibody drug in an antibody therapy of cancer is used as an active ingredient of a drug for enhancing cytotoxic activity of an antibody drug in an antibody therapy of cancer.
摘要翻译: 作为促进细胞毒活性的药物的活性成分,使用可通过用水解酶水解乳铁蛋白而获得的乳铁蛋白水解物混合物或乳铁蛋白部分肽,并具有增强抗体药物在癌症抗体治疗中的细胞毒活性的作用 的抗体药物在癌症的抗体治疗中。
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公开(公告)号:US07419667B2
公开(公告)日:2008-09-02
申请号:US10564302
申请日:2005-03-09
申请人: Kiyohiko Hatake , Yasuhito Terui , Yuji Mishima , Akio Yamada , Takuma Sakurai , Takehito Itoh
发明人: Kiyohiko Hatake , Yasuhito Terui , Yuji Mishima , Akio Yamada , Takuma Sakurai , Takehito Itoh
IPC分类号: A61K39/395 , C07K16/00
摘要: A lactoferrin hydrolysate mixture or lactoferrin partial peptide that can be obtained by hydrolyzing lactoferrin with a hydrolytic enzyme and has an action of enhancing cytotoxic activity of an antibody drug in an antibody therapy of cancer is used as an active ingredient of a drug for enhancing cytotoxic activity of an antibody drug in an antibody therapy of cancer.
摘要翻译: 作为促进细胞毒活性的药物的活性成分,使用可通过用水解酶水解乳铁蛋白而获得的乳铁蛋白水解物混合物或乳铁蛋白部分肽,并且具有增强抗体药物在癌症抗体治疗中的细胞毒活性的作用 的抗体药物在癌症的抗体治疗中。
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