摘要:
The present invention provides methods for treating tumors, which comprise the step of administering into tumor sites a minus-strand RNA viral vector encoding an immunostimulatory cytokine or cells introduced with the vector. The present invention also provides compositions for treating tumors, which comprise as an active ingredient the minus-strand RNA viral vector encoding an immunostimulatory cytokine or cells introduced with the vector. The present invention also provides kits for treating tumors, which comprise the minus-strand RNA viral vector encoding an immunostimulatory cytokine, and a tumor antigen or a vector expressing the antigen.
摘要:
The present invention provides methods for treating tumors, which comprise the step of administering into tumor sites a minus-strand RNA viral vector encoding an immunostimulatory cytokine or cells introduced with the vector. The present invention also provides compositions for treating tumors, which comprise as an active ingredient the minus-strand RNA viral vector encoding an immunostimulatory cytokine or cells introduced with the vector. The present invention also provides kits for treating tumors, which comprise the minus-strand RNA viral vector encoding an immunostimulatory cytokine, and a tumor antigen or a vector expressing the antigen.
摘要:
The present invention provides a brain tumor marker, characterized in that the brain tumor marker is at least one protein expressed in a brain tumor tissue and selected from the group of proteins having the amino acid sequences represented by SEQ ID NOS: 1 to 16, respectively, wherein the protein is expressed in at least one tissue selected from the group of the tissues of a highly malignant brain tumor, a low malignant brain tumor, a drug-sensitive brain tumor, and a drug-resistant brain tumor; a polynucleotide encoding the brain tumor marker; and a method of diagnosing brain tumors by using the brain tumor marker or the polynucleotide as an indicator.
摘要翻译:本发明提供一种脑肿瘤标志物,其特征在于,脑肿瘤标记物是至少一种在脑肿瘤组织中表达的蛋白质,分别选自具有SEQ ID NO:1至16所示氨基酸序列的蛋白质组 其中所述蛋白质在选自高恶性脑肿瘤,低恶性脑肿瘤,药物敏感性脑肿瘤和耐药性脑肿瘤的组织组中的至少一种组织中表达; 编码脑肿瘤标志物的多核苷酸; 以及通过使用脑肿瘤标记物或多核苷酸作为指标诊断脑肿瘤的方法。