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公开(公告)号:US20090214571A1
公开(公告)日:2009-08-27
申请号:US11913228
申请日:2006-07-21
IPC分类号: A61K39/395 , C12Q1/02 , C12Q1/68 , G01N33/68 , A61K31/7105 , A61K39/00 , A61K35/12 , C07K7/06 , A61P35/00
CPC分类号: G01N33/57419 , C07K16/18 , C07K16/3046 , G01N2500/00
摘要: Objective methods for detecting and diagnosing colon cancer are described herein. In one embodiment, the diagnostic method involves determining the expression level of TOM34 that discriminates between colon cancer cells and normal cells. Finally, the present invention provides methods of screening for therapeutic agents useful in the treatment of colon cancer, methods of treating colon cancer and method for vaccinating a subject against colon cancer.
摘要翻译: 本文描述了用于检测和诊断结肠癌的客观方法。 在一个实施方案中,诊断方法包括确定区分结肠癌细胞和正常细胞的TOM34的表达水平。 最后,本发明提供筛选可用于治疗结肠癌的治疗剂,治疗结肠癌的方法和接种个体对结肠癌的方法。