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公开(公告)号:US08822503B2
公开(公告)日:2014-09-02
申请号:US13081201
申请日:2011-04-06
申请人: Takanori Kawaguchi , Kengo Watatani , Keiko Fusegi , Masahiro Bohno , Hajime Asanuma , Shoichi Kuroda , Yudai Imai , Tomomichi Chonan , Nagaaki Sato , Shigeru Tokita , Shigetada Sasako , Takumi Okada , Keishi Hayashi , Shin Itoh , Noriko Saito , Rui Jibiki , Seishi Ishiyama , Hirofumi Ota
发明人: Takanori Kawaguchi , Kengo Watatani , Keiko Fusegi , Masahiro Bohno , Hajime Asanuma , Shoichi Kuroda , Yudai Imai , Tomomichi Chonan , Nagaaki Sato , Shigeru Tokita , Shigetada Sasako , Takumi Okada , Keishi Hayashi , Shin Itoh , Noriko Saito , Rui Jibiki , Seishi Ishiyama , Hirofumi Ota
IPC分类号: A61K31/4439 , C07D401/06
CPC分类号: C07D401/10 , C07D213/64 , C07D401/12 , C07D401/14 , C07D405/10 , C07D413/06 , C07D417/06 , C07D417/14
摘要: A 2-pyridone compound represented by the formula [1]: {wherein in the formula [1], the ring represented by A represents a benzene ring or a pyridine ring, X represents any of the structures represented by the formulas [3] shown below: V represents a single bond or a lower alkylene group, and W represents a single bond, an ether bond or a lower alkylene group (wherein the lower alkylene group may contain an ether bond)}, a tautomer or stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof is a compound that has an excellent GK activating effect and is useful as a pharmaceutical.
摘要翻译: 由式[1]表示的2-吡啶酮化合物:其中,在式[1]中,由A表示的环表示苯环或吡啶环,X表示由式[3]表示的任何结构 V表示单键或低级亚烷基,W表示单键,醚键或低级亚烷基(其中低级亚烷基可以含有醚键)},化合物的互变异构体或立体异构体, 其药学上可接受的盐或其溶剂合物是具有优异的GK活化作用并可用作药物的化合物。
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公开(公告)号:US20110237791A1
公开(公告)日:2011-09-29
申请号:US13081201
申请日:2011-04-06
申请人: Takanori KAWAGUCHI , Kengo WATATANI , Keiko FUSEGI , Masahiro BOHNO , Hajime ASANUMA , Shoichi KURODA , Yudai IMAI , Tomomichi CHONAN , Nagaaki SATO , Shigeru TOKITA , Shigetada SASAKO , Takumi OKADA , Keishi HAYASHI , Shin ITOH , Noriko SAITO , Rui JIBIKI , Seishi ISHIYAMA , Hirofumi OTA
发明人: Takanori KAWAGUCHI , Kengo WATATANI , Keiko FUSEGI , Masahiro BOHNO , Hajime ASANUMA , Shoichi KURODA , Yudai IMAI , Tomomichi CHONAN , Nagaaki SATO , Shigeru TOKITA , Shigetada SASAKO , Takumi OKADA , Keishi HAYASHI , Shin ITOH , Noriko SAITO , Rui JIBIKI , Seishi ISHIYAMA , Hirofumi OTA
IPC分类号: C07D213/64 , C07D401/12 , C07D401/06 , C07D405/06 , C07D413/14
CPC分类号: C07D401/10 , C07D213/64 , C07D401/12 , C07D401/14 , C07D405/10 , C07D413/06 , C07D417/06 , C07D417/14
摘要: A 2-pyridone compound represented by the formula [1]: {wherein in the formula [1], the ring represented by A represents a benzene ring or a pyridine ring, X represents any of the structures represented by the formulas [3] shown below: V represents a single bond or a lower alkylene group, and W represents a single bond, an ether bond or a lower alkylene group (wherein the lower alkylene group may contain an ether bond)}, a tautomer or stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof is a compound that has an excellent GK activating effect and is useful as a pharmaceutical.
摘要翻译: 由式[1]表示的2-吡啶酮化合物:其中,在式[1]中,由A表示的环表示苯环或吡啶环,X表示由式[3]表示的任何结构 V表示单键或低级亚烷基,W表示单键,醚键或低级亚烷基(其中低级亚烷基可以含有醚键)},化合物的互变异构体或立体异构体, 其药学上可接受的盐或其溶剂合物是具有优异的GK活化作用并可用作药物的化合物。
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