公开(公告)号：US20060043359A1

公开(公告)日：2006-03-02

申请号：US10535412

申请日：2004-06-24

申请人： Yuki Masuda ,  Nobuo Kobayashi

发明人： Yuki Masuda ,  Nobuo Kobayashi

IPC分类号： H01L29/08

CPC分类号： H01L51/0545 ,  B82Y10/00 ,  H01L51/0516 ,  H01L51/0595

摘要： An organic FET 1 comprises a substrate 2 on which a gate insulation film 41 and a reformed layer 43 are formed in this order, and a source electrode 6 and a drain electrode 8 are further arranged thereon at a predetermined distance from each other, and furthermore, an organic semiconductor layer 10 is formed on and between the electrodes 6 and 8. The reformed layer 43 fixed on the gate insulation film 41 and attached to the organic semiconductor layer 10 contains a specific compound containing the CN group or is composed of only a specific compound containing the CN group.

摘要翻译： 有机FET1包括其上依次形成有栅极绝缘膜41和重整层43的基板2，并且在其上以预定的距离进一步配置源电极6和漏电极8，此外 在电极6和8之间形成有机半导体层10。 固定在栅极绝缘膜41上并安装在有机半导体层10上的重整层43含有包含CN基团的特定化合物，或仅由含有CN基团的特定化合物构成。

公开(公告)号：US20070027069A1

公开(公告)日：2007-02-01

申请号：US11342904

申请日：2006-01-30

申请人： Yuki Masuda ,  Hazuki Ikumoto ,  Noriko Kodama ,  Hiroaki Nanba

发明人： Yuki Masuda ,  Hazuki Ikumoto ,  Noriko Kodama ,  Hiroaki Nanba

IPC分类号： A61K38/16 ,  C07K14/375

CPC分类号： C07K14/375 ,  A61K38/00

摘要： It is an objective of the present invention to develop a Grifola-derived glucan-protein complex that has a molecular weight lower than that of a conventionally known high-molecular-weight glucan-protein complex and has advanced immunopotentiating activity and antitumor activity. The glucan-protein complex of interest was obtained through the following 1) to 5): 1) a step of thermally extracting mycelia or fruit bodies of Grifola with water; 2) a step of adding alcohol to the obtained water-soluble extract fraction to a final concentration between 20% and 70% by volume, allowing the resulting solution to stand at a temperature between 1° C. and 25° C., and collecting matter floating on or in the solution or adhering to the wall surface of a vessel; 3) a step of dissolving the collected matter in water and collecting non-adsorbed fraction by anion-exchange column chromatography; 4) a step of adding alcohol to the resulting solution to a final concentration between 20% and 50% by volume, allowing the solution to stand at a temperature between 1° C and 25° C., and removing the precipitate that had formed therein; and 5) a step of adding alcohol to the resulting solution to a final concentration between 40% to 99% by volume, allowing the resultant to stand at a temperature between 1° C. to 25° C., and collecting the precipitate that had formed therein.

摘要翻译： 本发明的目的是开发具有比常规已知的高分子量葡聚糖 - 蛋白复合物低的分子量的Grifola衍生的葡聚糖蛋白复合物，并且具有先进的免疫增强活性和抗肿瘤活性。 通过以下1）至5）获得目的葡聚糖蛋白复合物：1）用水热提取奇果菌的菌丝体或果实的步骤; 2）向得到的水溶性提取液馏分中添加醇至20体积％〜70体积％的终浓度的步骤，使得到的溶液在1℃〜25℃的温度下放置，收集 漂浮在溶液中或溶液中的物质或附着在容器的壁表面上; 3）将收集的物质溶解在水中并通过阴离子交换柱层析收集非吸附级分的步骤; 4）向所得溶液中加入醇至终浓度为20体积％至50体积％的步骤，使溶液在1℃至25℃之间的温度下静置，并除去其中形成的沉淀物 ; 和5）向所得溶液中加入醇至终浓度为40体积％至99体积％之间的步骤，使其在1℃至25℃之间的温度下静置，并收集具有 在其中形成。

公开(公告)号：US07361926B2

公开(公告)日：2008-04-22

申请号：US10535412

申请日：2004-06-24

申请人： Yuki Masuda ,  Nobuo Kobayashi

发明人： Yuki Masuda ,  Nobuo Kobayashi

IPC分类号： H01L29/08 ,  H01L35/24 ,  H01L51/00

CPC分类号： H01L51/0545 ,  B82Y10/00 ,  H01L51/0516 ,  H01L51/0595

摘要： An organic FET 1 comprises a substrate 2 on which a gate insulation film 41 and a reformed layer 43 are formed in this order, and a source electrode 6 and a drain electrode 8 are further arranged thereon at a predetermined distance from each other, and furthermore, an organic semiconductor layer 10 is formed on and between the electrodes 6 and 8. The reformed layer 43 fixed on the gate insulation film 41 and attached to the organic semiconductor layer 10 contains a specific compound containing the CN group or is composed of only a specific compound containing the CN group.

摘要翻译： 有机FET1包括其上依次形成有栅极绝缘膜41和重整层43的基板2，并且在其上以预定的距离进一步配置源电极6和漏电极8，此外 在电极6和8之间形成有机半导体层10。 固定在栅极绝缘膜41上并安装在有机半导体层10上的重整层43含有包含CN基团的特定化合物，或仅由含有CN基团的特定化合物构成。