公开(公告)号：US07697976B2

公开(公告)日：2010-04-13

申请号：US10586272

申请日：2005-01-18

申请人： Jinguang Wu ,  Yuanfu Zhang ,  Yizhuang Xu ,  Qingbo Li ,  Shifu Weng ,  Limin Yang ,  Li Zhang ,  Weijin Zhou ,  Zhanlan Yang ,  Weihong Li ,  Huizhong Wu ,  Rongye Gong ,  Xuejun Gao ,  Duanfu Xu ,  Ying Zhao ,  Zhi Xu ,  Nengwei Zhang ,  Lixin Wang ,  Kaihua Sun ,  Xin Peng ,  Yufeng Liu ,  Xuejun Sun ,  Xiaofeng Ling ,  Su Zhou ,  Zhi Liu ,  Guoqiao Lai ,  Jianxiong Jiang ,  Qinghua Pan ,  Qiguang Wu ,  Guangyan Yu ,  Bingbing Wang

发明人： Jinguang Wu ,  Yuanfu Zhang ,  Yizhuang Xu ,  Qingbo Li ,  Shifu Weng ,  Limin Yang ,  Li Zhang ,  Weijin Zhou ,  Zhanlan Yang ,  Weihong Li ,  Huizhong Wu ,  Rongye Gong ,  Xuejun Gao ,  Duanfu Xu ,  Ying Zhao ,  Zhi Xu ,  Nengwei Zhang ,  Lixin Wang ,  Kaihua Sun ,  Xin Peng ,  Yufeng Liu ,  Xuejun Sun ,  Xiaofeng Ling ,  Su Zhou ,  Zhi Liu ,  Guoqiao Lai ,  Jianxiong Jiang ,  Qinghua Pan ,  Qiguang Wu ,  Guangyan Yu ,  Bingbing Wang

IPC分类号： A61B5/02

CPC分类号： A61B5/0059 ,  A61B5/6848 ,  A61B5/7257

摘要： The invention relates to a non-invasive method to diagnose the changes of molecular structures of organism tissues from body surface and a dedicated apparatus. The apparatus is comprised of a Fourier Transform infrared spectrometer and a set of additional accessories. Said additional accessories include a mid-IR fiber optics sampling attachment, a fiber coupling part, and an infrared detector part. The detection method is comprised of placing the ATR probe of the dedicated apparatus on the skin surface of a region to be tested, and scanning more than one time in which the resolution of the apparatus is 1-32 cm−1 and the range of the spectrum is 800-4000 cm−1. It is possible to detect changes in molecular structures of living biological tissues in the early stages of cancer, and testees will not feel uncomfortable during testing. The method is easy to operate, quick, accurate, and it doesn't harm the body.

摘要翻译： 本发明涉及用于诊断来自身体表面的生物体组织的分子结构的变化的非侵入性方法和专用设备。 该装置由傅里叶变换红外光谱仪和一组附加附件组成。 所述附加附件包括中红外光纤采样附件，光纤耦合部件和红外探测器部件。 检测方法包括将专用装置的ATR探针放置在要测试的区域的皮肤表面上，扫描多于一次，其中装置的分辨率为1-32cm-1，并且扫描范围 光谱为800-4000cm-1。 在癌症早期阶段可以检测生物体组织的分子结构变化，受试者在测试过程中不会感到不适。 该方法易于操作，快速，准确，不伤身体。